Skip to main content

Articles

Page 29 of 108

  1. The distribution of histopathological features of invasive breast tumors in BRCA1 or BRCA2 germline mutation carriers differs from that of individuals with no known mutation. Histopathological features thus have ...

    Authors: Amanda B Spurdle, Fergus J Couch, Michael T Parsons, Lesley McGuffog, Daniel Barrowdale, Manjeet K Bolla, Qin Wang, Sue Healey, Rita Katharina Schmutzler, Barbara Wappenschmidt, Kerstin Rhiem, Eric Hahnen, Christoph Engel, Alfons Meindl, Nina Ditsch, Norbert Arnold…
    Citation: Breast Cancer Research 2014 16:3419
    Content type: Research article Published on:

  2. The POU class 1 homeobox 1 transcription factor (POU1F1, also known as Pit-1) is expressed in the mammary gland and its overexpression induces profound phenotypic changes in proteins involved in cell prolifera...

    Authors: Juan Sendon-Lago, Samuel Seoane, Noemi Eiro, Maria A Bermudez, Manuel Macia, Tomas Garcia-Caballero, Francisco J Vizoso and Roman Perez-Fernandez
    Citation: Breast Cancer Research 2014 16:505
    Content type: Research article Published on:

  3. The cell of origin for estrogen receptor α (ERα) positive breast cancer is probably a luminal stem cell in the terminal duct lobular units. To model these cells we have used the murine myoepithelial layer in t...

    Authors: Stephanie Verbeke, Elodie Richard, Elodie Monceau, Xenia Schmidt, Benoit Rousseau, Valerie Velasco, David Bernard, Herve Bonnefoi, Gaetan MacGrogan and Richard D Iggo
    Citation: Breast Cancer Research 2014 16:504
    Content type: Research article Published on:

    The Erratum to this article has been published in Breast Cancer Research 2015 17:126

  4. High mammographic density is an established breast cancer risk factor, and circulating oestrogen influences oestrogen-regulating gene expression in breast cancer development. However, less is known about the i...

    Authors: Vidar G Flote, Anne-Sofie Furberg, Anne McTiernan, Hanne Frydenberg, Giske Ursin, Anita Iversen, Trygve Lofteroed, Peter T Ellison, Erik A Wist, Thore Egeland, Tom Wilsgaard, Karen W Makar, Jenny Chang-Claude and Inger Thune
    Citation: Breast Cancer Research 2014 16:499
    Content type: Research article Published on:

  5. Human Epidermal Growth Factor Receptor (ERBB4/HER4) belongs to the Epidermal Growth Factor receptor/ERBB family of receptor tyrosine kinases. While ERBB1, ERBB2 and ERBB3 are often overexpressed or activated i...

    Authors: Vikram B Wali, Maureen Gilmore-Hebert, Ramanaiah Mamillapalli, Jonathan W Haskins, Kari J Kurppa, Klaus Elenius, Carmen J Booth and David F Stern
    Citation: Breast Cancer Research 2014 16:501
    Content type: Research article Published on:

  6. Previous work from this laboratory demonstrated that magnetic resonance imaging (MRI) detects early murine mammary cancers and reliably differentiates between in situ and invasive cancer. Based on this previous w...

    Authors: Xiaobing Fan, Devkumar Mustafi, Erica Markiewicz, Marta Zamora, James Vosicky, Abby Leinroth, Jeffrey Mueller, Kay Macleod, Suzanne D Conzen and Gregory S Karczmar
    Citation: Breast Cancer Research 2014 16:495
    Content type: Research article Published on:

  7. Several innate immunity genes are overexpressed in human cancers and their roles remain controversial. Bone marrow stromal antigen 2 (BST-2) is one such gene whose role in cancer is not clear. BST-2 is a uniqu...

    Authors: Wadie D Mahauad-Fernandez, Kris A DeMali, Alicia K Olivier and Chioma M Okeoma
    Citation: Breast Cancer Research 2014 16:493
    Content type: Research article Published on:

  8. This study helps to define the implications of breast cancer anti-estrogen resistance 3 (BCAR3) in breast cancer and extends the current understanding of its molecular mechanism of action. BCAR3 has been shown...

    Authors: Jimin Guo, Lucie Canaff, Charles Vincent Rajadurai, Nadège Fils-Aimé, Jun Tian, Meiou Dai, Juliana Korah, Manuel Villatoro, Morag Park, Suhad Ali and Jean-Jacques Lebrun
    Citation: Breast Cancer Research 2014 16:476
    Content type: Research article Published on:

  9. Nuclear accumulation of β-catenin is important for cancer development and it is found to overlap with p68 (DDX5) immunoreactivity in most breast cancers, as indicated by both clinical investigations and studie...

    Authors: Kiran Kumar Naidu Guturi, Moumita Sarkar, Arijit Bhowmik, Nilanjana Das and Mrinal Kanti Ghosh
    Citation: Breast Cancer Research 2014 16:496
    Content type: Research article Published on:

  11. Extracellular matrix protein 1 (ECM1) is a secreted glycoprotein with putative functions in cell proliferation, angiogenesis and differentiation. Expression of ECM1 in several types of carcinoma suggests that ...

    Authors: Kyung-min Lee, Keesoo Nam, Sunhwa Oh, Juyeon Lim, Young-Pil Kim, Jong Won Lee, Jong-Han Yu, Sei-Hyun Ahn, Sung-Bae Kim, Dong-Young Noh, Taehoon Lee and Incheol Shin
    Citation: Breast Cancer Research 2014 16:479
    Content type: Research article Published on:

    The Correction to this article has been published in Breast Cancer Research 2019 21:45

  12. Mammographic density (MD) is a strong biomarker of breast cancer risk. MD increases after women start estrogen plus progestin therapy (EPT) and decreases after women quit EPT. A large interindividual variation...

    Authors: Eunjung Lee, Jianning Luo, Yu-Chen Su, Juan Pablo Lewinger, Fredrick R Schumacher, David Van Den Berg, Anna H Wu, Leslie Bernstein and Giske Ursin
    Citation: Breast Cancer Research 2014 16:477
    Content type: Research article Published on:

  13. The activation of the phosphoinositide 3-kinase (PI3K)/AKT signalling pathway is one the most frequent genetic events in breast cancer, consequently the development of PI3K inhibitors has attracted much attent...

    Authors: Richard Hill, Ravi Kiran Reddy Kalathur, Sergio Callejas, Laura Colaço, Ricardo Brandão, Beatriz Serelde, Antonio Cebriá, Carmen Blanco-Aparicio, Joaquín Pastor, Matthias Futschik, Ana Dopazo and Wolfgang Link
    Citation: Breast Cancer Research 2014 16:482
    Content type: Research article Published on:

  14. The transcription factor GATA3 is involved in mammary gland development and is crucial for the maintenance of the differentiated status of luminal epithelial cells. The role of GATA3 in breast cancer as a tumo...

    Authors: Franco Izzo, Florencia Mercogliano, Leandro Venturutti, Mercedes Tkach, Gloria Inurrigarro, Roxana Schillaci, Leandro Cerchietti, Patricia V Elizalde and Cecilia J Proietti
    Citation: Breast Cancer Research 2014 16:491
    Content type: Research article Published on:

  15. Luminal, estrogen receptor-positive (ER+) breast cancers can metastasize but lie dormant for years before recurrences prove lethal. Understanding the roles of estrogen (E) or progestin (P) in development of lumin...

    Authors: Ndiya Ogba, Nicole G Manning, Brian S Bliesner, S Kelly Ambler, James M Haughian, Mauricio P Pinto, Paul Jedlicka, Kristiina Joensuu, Päivi Heikkilä and Kathryn B Horwitz
    Citation: Breast Cancer Research 2014 16:489
    Content type: Research article Published on:

  16. Homologous recombination (HR) DNA repair is of clinical relevance in breast cancer. Three DNA-based homologous recombination deficiency (HRD) scores (HRD-loss of heterozygosity score (LOH), HRD-telomeric allel...

    Authors: Kirsten M Timms, Victor Abkevich, Elisha Hughes, Chris Neff, Julia Reid, Brian Morris, Saritha Kalva, Jennifer Potter, Thanh V Tran, Jian Chen, Diana Iliev, Zaina Sangale, Eliso Tikishvili, Michael Perry, Andrey Zharkikh, Alexander Gutin…
    Citation: Breast Cancer Research 2014 16:475
    Content type: Research article Published on:

  18. Spot14 (S14), encoded by the THRSP gene, regulates de novo fatty acid synthesis in the liver, adipose, and lactating mammary gland. We recently showed that S14 stimulated fatty acid synthase (FASN) activity in vi...

    Authors: Elizabeth A Wellberg, Michael C Rudolph, Andrew S Lewis, Nuria Padilla-Just, Paul Jedlicka and Steven M Anderson
    Citation: Breast Cancer Research 2014 16:481
    Content type: Research article Published on:

  19. Studies have identified multi-potent stem cells in the adult mammary gland. More recent studies have suggested that the embryonic mammary gland may also contain stem/progenitor cells that contribute to initial...

    Authors: Kata Boras-Granic, Pamela Dann and John J Wysolmerski
    Citation: Breast Cancer Research 2014 16:487
    Content type: Research article Published on:

  21. Genetic and molecular signatures have been incorporated into cancer prognosis prediction and treatment decisions with good success over the past decade. Clinically, these signatures are usually used in early-s...

    Authors: Sari S Khaleel, Erik H Andrews, Matthew Ung, James DiRenzo and Chao Cheng
    Citation: Breast Cancer Research 2014 16:486
    Content type: Research article Published on:

  22. Adrenomedullin (AM) is secreted by breast cancer cells and increased by hypoxia. It is a multifunctional peptide that stimulates angiogenesis and proliferation. The peptide is also a potent paracrine stimulato...

    Authors: Valerie A Siclari, Khalid S Mohammad, Douglas R Tompkins, Holly Davis, C Ryan McKenna, Xianghong Peng, Lisa L Wessner, Maria Niewolna, Theresa A Guise, Attaya Suvannasankha and John M Chirgwin
    Citation: Breast Cancer Research 2014 16:458
    Content type: Research article Published on:

  23. Tumor microenvironment immunity is associated with breast cancer outcome. A high lymphocytic infiltration has been associated with response to neoadjuvant chemotherapy, but the contribution to response and pro...

    Authors: Elena García-Martínez, Ginés Luengo Gil, Asunción Chaves Benito, Enrique González-Billalabeitia, María Angeles Vicente Conesa, Teresa García García, Elisa García-Garre, Vicente Vicente and Francisco Ayala de la Peña
    Citation: Breast Cancer Research 2014 16:488
    Content type: Research article Published on:

  24. Clinical dormancy is frequently observed in breast cancer. In the present study, we aimed to characterize circulating tumor cells (CTCs) in dormancy candidates (DC) with early breast cancer in terms of prolife...

    Authors: Maria Spiliotaki, Dimitris Mavroudis, Kyriaki Kapranou, Harris Markomanolaki, Galatea Kallergi, Filippos Koinis, Kostas Kalbakis, Vassilis Georgoulias and Sofia Agelaki
    Citation: Breast Cancer Research 2014 16:485
    Content type: Research article Published on:

  25. For many decades, developmental biologists and cancer researchers alike have been trying to understand the relationship between the basal and luminal cell compartments in the mouse mammary epithelium. Delineat...

    Authors: Renée van Amerongen
    Citation: Breast Cancer Research 2014 16:480
    Content type: Viewpoint Published on:

  26. The establishment of drug resistance following treatment with chemotherapeutics is strongly associated with poor clinical outcome in patients, and drugs that target chemoresistant tumors have the potential to ...

    Authors: Rachel M Vaden, Keith M Gligorich, Ranjan Jana, Matthew S Sigman and Bryan E Welm
    Citation: Breast Cancer Research 2014 16:472
    Content type: Research article Published on:

  27. Breast cancer is currently the most frequent, fatal cancer of women in western countries. While estrogens have a widely understood involvement in breast cancer, a significant but not yet fully understood role ...

    Authors: Jaesung Choi, Basil Psarommatis, Yan Ru Gao, Yu Zheng, David J Handelsman and Ulla Simanainen
    Citation: Breast Cancer Research 2014 16:483
    Content type: Review Published on:

  28. Triple Negative Breast Cancers (TNBC) represent about 12% to 20% of all breast cancers (BC) and have a worse outcome compared to other BC subtypes. TNBC often show a deficiency in DNA double-strand break repai...

    Authors: Sébastien Toffoli, Isabelle Bar, Fadi Abdel-Sater, Paul Delrée, Pascale Hilbert, Frédéric Cavallin, Fabrice Moreau, Wim Van Criekinge, Magali Lacroix-Triki, Mario Campone, Anne-Laure Martin, Henri Roché, Jean-Pascal Machiels, Javier Carrasco and Jean-Luc Canon
    Citation: Breast Cancer Research 2014 16:466
    Content type: Research article Published on:

  29. GATA binding protein 3 (GATA3) is a regulator of mammary luminal cell differentiation, and an estrogen receptor (ER) associated marker in breast cancer. Tumor suppressor functions of GATA3 have been demonstrat...

    Authors: Helit Cohen, Rotem Ben-Hamo, Moriah Gidoni, Ilana Yitzhaki, Renana Kozol, Alona Zilberberg and Sol Efroni
    Citation: Breast Cancer Research 2014 16:464
    Content type: Research article Published on:

  30. miR-31 is well known as an anti-metastatic microRNA (miRNA) in the context of breast cancer. However, to date the mechanism of regulation of this miRNA has yet to be elucidated. The recent publication by Viré et ...

    Authors: Laoighse Mulrane, William M Gallagher and Darran P O’Connor
    Citation: Breast Cancer Research 2014 16:467
    Content type: Viewpoint Published on:

  31. Earlier menarche is related to subsequent breast cancer risk, yet international differences in the age and tempo of other pubertal milestones and their relationships with body mass index (BMI) are not firmly e...

    Authors: Lauren C Houghton, Gillian D Cooper, Gillian R Bentley, Mark Booth, Osul A Chowdhury, Rebecca Troisi, Regina G Ziegler, Robert N Hoover and Hormuzd A Katki
    Citation: Breast Cancer Research 2014 16:469
    Content type: Research article Published on:

  32. The miR-183/-96/-182 cluster is a conserved polycistronic microRNA (miRNA) cluster which is highly expressed in most breast cancers. Although there are some sporadic reports which demonstrate the importance of ea...

    Authors: Pei Li, Cheng Sheng, Lingling Huang, Hui Zhang, Lihua Huang, Zeneng Cheng and Qubo Zhu
    Citation: Breast Cancer Research 2014 16:473
    Content type: Research article Published on:

  33. Estrogen inhibition is effective in preventing breast cancer in only up to 50% of women with precancerous lesions and many experience side effects that are poorly tolerated. As insulin-like growth factor I (IG...

    Authors: Baljit Singh, Julia A Smith, Deborah M Axelrod, Pietro Ameri, Heather Levitt, Ann Danoff, Martin Lesser, Cristina de Angelis, Irineu Illa-Bochaca, Sara Lubitz, Daniel Huberman, Farbod Darvishian and David L Kleinberg
    Citation: Breast Cancer Research 2014 16:463
    Content type: Research article Published on:

  34. Aberrant expression of the embryonic stem cell marker Sox2 has been reported in breast cancer (BC). We previously identified two phenotypically distinct BC cell subsets separated based on their differential re...

    Authors: Karen Jung, Peng Wang, Nidhi Gupta, Keshav Gopal, Fang Wu, Xiaoxia Ye, Abdulraheem Alshareef, Gilbert Bigras, Todd P McMullen, Bassam S Abdulkarim and Raymond Lai
    Citation: Breast Cancer Research 2014 16:470
    Content type: Research article Published on:

  36. XBP1 is a well-characterized regulator of the unfolding protein response that is activated in response to unfolded or misfolded proteins or nutrient deprivation. The conventional wisdom is that XBP1 is activated ...

    Authors: Melissa M Keenan, Chien-Kuang Cornelia Ding and Jen-Tsan Chi
    Citation: Breast Cancer Research 2014 16:471
    Content type: Viewpoint Published on:
Submit manuscript

Follow

Annual Journal Metrics

  • 2022 Citation Impact
    7.4 - 2-year Impact Factor
    7.4 - 5-year Impact Factor
    1.764 - SNIP (Source Normalized Impact per Paper)
    2.408 - SJR (SCImago Journal Rank)

    2023 Speed
    20 days submission to first editorial decision for all manuscripts (Median)
    129 days submission to accept (Median)

    2023 Usage 
    2,432,781 downloads
    1,561 Altmetric mentions

Breast Cancer Research

ISSN: 1465-542X

Contact us