Skip to content



Sort by
Page 1 of 180
  1. Content type: Research article

    Psychiatric medications are widely prescribed in the USA. Many antipsychotics cause serum hyperprolactinemia as an adverse side effect; prolactin-Janus kinase 2 (JAK2)-signal transducer and activator of transc...

    Authors: A. N. Johnston, W. Bu, S. Hein, S. Garcia, L. Camacho, L. Xue, L. Qin, C. Nagi, S. G. Hilsenbeck, J. Kapali, K. Podsypanina, J. Nangia and Y. Li

    Citation: Breast Cancer Research 2018 20:42

    Published on:

  2. Content type: Research article

    The RhoA activating protein Net1 contributes to breast cancer cell proliferation, motility, and invasion in vitro, yet little is known about its roles in mammary gland tumorigenesis and metastasis.

    Authors: Yan Zuo, Arzu Ulu, Jeffrey T. Chang and Jeffrey A. Frost

    Citation: Breast Cancer Research 2018 20:41

    Published on:

  3. Content type: Short report

    Detection of circulating ESR1 mutations is associated with acquired resistance to aromatase inhibitor (AI) in metastatic breast cancer. Until now, the presence of circulating ESR1 mutations at the end of adjuvant...

    Authors: Violette Allouchery, Ludivine Beaussire, Anne Perdrix, David Sefrioui, Laetitia Augusto, Cécile Guillemet, Nasrin Sarafan-Vasseur, Frédéric Di Fiore and Florian Clatot

    Citation: Breast Cancer Research 2018 20:40

    Published on:

  4. Content type: Review

    Atypical ductal hyperplasia (ADH) is a common diagnosis in the mammographic era and a significant clinical problem with wide variation in diagnosis and treatment. After a diagnosis of ADH on biopsy a proportio...

    Authors: Tanjina Kader, Prue Hill, Emad A. Rakha, Ian G. Campbell and Kylie L. Gorringe

    Citation: Breast Cancer Research 2018 20:39

    Published on:

  5. Content type: Research article

    Texture patterns have been shown to improve breast cancer risk segregation in addition to area-based mammographic density. The additional value of texture pattern scores on top of volumetric mammographic densi...

    Authors: Johanna O. P. Wanders, Carla H. van Gils, Nico Karssemeijer, Katharina Holland, Michiel Kallenberg, Petra H. M. Peeters, Mads Nielsen and Martin Lillholm

    Citation: Breast Cancer Research 2018 20:36

    Published on:

  6. Content type: Research article

    The majority of estrogen receptor-positive (ERα+) breast cancers respond to endocrine therapies. However, resistance to endocrine therapies is common in 30% of cases, which may be due to altered ERα signaling and...

    Authors: Maria B. Padua, Poornima Bhat-Nakshatri, Manjushree Anjanappa, Mayuri S. Prasad, Yangyang Hao, Xi Rao, Sheng Liu, Jun Wan, Yunlong Liu, Kyle McElyea, Max Jacobsen, George Sandusky, Sandra Althouse, Susan Perkins and Harikrishna Nakshatri

    Citation: Breast Cancer Research 2018 20:35

    Published on:

  7. Content type: Research article

    Cognitive decline is among the most feared treatment-related outcomes of older adults with cancer. The majority of older patients with breast cancer self-report cognitive problems during and after chemotherapy...

    Authors: Bihong T. Chen, Sean K. Sethi, Taihao Jin, Sunita K. Patel, Ningrong Ye, Can-Lan Sun, Russell C. Rockne, E. Mark Haacke, James C. Root, Andrew J. Saykin, Tim A. Ahles, Andrei I. Holodny, Neal Prakash, Joanne Mortimer, James Waisman, Yuan Yuan…

    Citation: Breast Cancer Research 2018 20:38

    Published on:

  8. Content type: Research article

    Rapidly evolving understanding of cancer biology has presented novel opportunities to translate that understanding into clinically relevant therapy. Palbociclib, a novel, first-in-class cyclin-dependent kinase...

    Authors: J. K. Kish, M. A. Ward, D. Garofalo, H. V. Ahmed, L. McRoy, J. Laney, G. Zanotti, J. Braverman, H. Yu and B. A. Feinberg

    Citation: Breast Cancer Research 2018 20:37

    Published on:

  9. Content type: Research Article

    The main purpose was to investigate the correlation between magnetic resonance imaging (MRI)-based response patterns halfway through neoadjuvant chemotherapy and immunotherapy (NAC) and pathological tumor resp...

    Authors: Briete Goorts, Kelly M. A. Dreuning, Janneke B. Houwers, Loes F. S. Kooreman, Evert-Jan G. Boerma, Ritse M. Mann, Marc B. I. Lobbes and Marjolein L. Smidt

    Citation: Breast Cancer Research 2018 20:34

    Published on:

  10. Content type: Research article

    Long noncoding RNAs (LncRNAs) represent a class of widespread and diverse endogenous RNAs that can posttranscriptionally regulate gene expression through the interaction with RNA-binding proteins and micro RNA...

    Authors: Yanchun Zhou, Xiuhua Meng, Shaoying Chen, Wei Li, Delin Li, Robert Singer and Wei Gu

    Citation: Breast Cancer Research 2018 20:32

    Published on:

  11. Content type: Research article

    Breast cancer prognosis is strongly associated with tumor size at diagnosis. We aimed to identify factors associated with diagnosis of large (> 2 cm) compared to small tumors, and to examine implications for l...

    Authors: Fredrik Strand, Keith Humphreys, Johanna Holm, Mikael Eriksson, Sven Törnberg, Per Hall, Edward Azavedo and Kamila Czene

    Citation: Breast Cancer Research 2018 20:31

    Published on:

  12. Content type: Research Article

    Younger age at onset of breast development, which has been declining in recent decades, is associated with increased breast cancer risk independent of age at menarche. Given the need to study the drivers of th...

    Authors: Lauren C. Houghton, Julia A. Knight, Mary Jane De Souza, Mandy Goldberg, Melissa L. White, Karen O’Toole, Wendy K. Chung, Angela R. Bradbury, Mary B. Daly, Irene L. Andrulis, Esther M. John, Saundra S. Buys and Mary Beth Terry

    Citation: Breast Cancer Research 2018 20:33

    Published on:

  13. Content type: Research Article

    The ataxia telangiectasia mutated (ATM) gene is a moderate-risk breast cancer susceptibility gene; germline loss-of-function variants are found in up to 3% of hereditary breast and ovarian cancer (HBOC) families ...

    Authors: Anne-Laure Renault, Noura Mebirouk, Laetitia Fuhrmann, Guillaume Bataillon, Eve Cavaciuti, Dorothée Le Gal, Elodie Girard, Tatiana Popova, Philippe La Rosa, Juana Beauvallet, Séverine Eon-Marchais, Marie-Gabrielle Dondon, Catherine Dubois d’Enghien, Anthony Laugé, Walid Chemlali, Virginie Raynal…

    Citation: Breast Cancer Research 2018 20:28

    Published on:

  14. Content type: Research article

    Leukocyte telomere length (LTL) and mitochondrial genome (mtDNA) copy number and deletions have been proposed as risk markers for various cancer types, including breast cancer (BC).

    Authors: Daniele Campa, Myrto Barrdahl, Aurelia Santoro, Gianluca Severi, Laura Baglietto, Hanane Omichessan, Rosario Tumino, H. B(as). Bueno-de-Mesquita, Petra H. Peeters, Elisabete Weiderpass, Maria-Dolores Chirlaque, Miguel Rodríguez-Barranco, Antonio Agudo, Marc Gunter, Laure Dossus, Vittorio Krogh…

    Citation: Breast Cancer Research 2018 20:29

    Published on:

  15. Content type: Research Article

    Patients with breast cancer who have a pathologic complete response (pCR) to neoadjuvant chemotherapy (NACT) have improved survival. We hypothesize that once pCR has been achieved, there is no difference in subse...

    Authors: Anna Weiss, Sami I. Bashour, Kenneth Hess, Alastair M. Thompson and Nuhad K. Ibrahim

    Citation: Breast Cancer Research 2018 20:27

    Published on:

  16. Content type: Research article

    The recommendation for chemotherapy in early-stage breast cancer patients has been refined by the 21-gene Recurrence Score. However, uncertainty remains whether patients in the Intermediate Risk category benef...

    Authors: Jonathan Chen, Xian Wu, Paul J. Christos, Silvia Formenti and Himanshu Nagar

    Citation: Breast Cancer Research 2018 20:26

    Published on:

  17. Content type: Research Article

    The isocitrate dehydrogenase (IDH) gene family expresses key functional metabolic enzymes in the Krebs cycle and mediates the epigenetic reprogramming, which serves as an important biomarker of breast cancer. ...

    Authors: Wen-Shan Liu, Shih-Hsuan Chan, Hong-Tai Chang, Guan-Cheng Li, Ya-Ting Tu, Hui-Hwa Tseng, Ting-Ying Fu, Hui-Yu Chang, Huei-Han Liou, Luo-Ping Ger and Kuo-Wang Tsai

    Citation: Breast Cancer Research 2018 20:25

    Published on:

  18. Content type: Research article

    The interaction of breast cancer cells with other cells in the tumor microenvironment plays an important role in metastasis. Invasion and intravasation, two critical steps in the metastatic process, are influe...

    Authors: Ramon M. Cabrera, Serena P. H. Mao, Chinmay R. Surve, John S. Condeelis and Jeffrey E. Segall

    Citation: Breast Cancer Research 2018 20:24

    Published on:

  19. Content type: Research Article

    Mammographic density (MD) is an established predictor of risk of a first breast cancer, but the relationship of MD to contralateral breast cancer (CBC) risk is not clear, including the roles of age, mammogram ...

    Authors: Julia A. Knight, Kristina M. Blackmore, Jing Fan, Kathleen E. Malone, Esther M. John, Charles F. Lynch, Celine M. Vachon, Leslie Bernstein, Jennifer D. Brooks, Anne S. Reiner, Xiaolin Liang, Meghan Woods and Jonine L. Bernstein

    Citation: Breast Cancer Research 2018 20:23

    Published on:

  20. Content type: Research Article

    Perfusion of breast cancer tissue limits oxygen availability and metabolism but angiogenesis inhibitors have hitherto been unsuccessful for breast cancer therapy. In order to identify abnormalities and possibl...

    Authors: Anne Sofie Froelunde, Marit Ohlenbusch, Kristoffer B. Hansen, Nicolai Jessen, Sukhan Kim and Ebbe Boedtkjer

    Citation: Breast Cancer Research 2018 20:20

    Published on:

  21. Content type: Research Article

    Early-onset breast cancer (EOBC) affects about one in 300 women aged 40 years or younger and is associated with worse outcomes than later onset breast cancer. This study explored novel serum proteins as surrog...

    Authors: Bashar Zeidan, Antigoni Manousopoulou, Diana J. Garay-Baquero, Cory H. White, Samantha E. T. Larkin, Kathleen N. Potter, Theodoros I. Roumeliotis, Evangelia K. Papachristou, Ellen Copson, Ramsey I. Cutress, Stephen A. Beers, Diana Eccles, Paul A. Townsend and Spiros D. Garbis

    Citation: Breast Cancer Research 2018 20:19

    Published on:

  22. Content type: Research Article

    Phosphatase and tensin homolog (PTEN) is one of the most frequently inactivated tumor suppressors in breast cancer. While PTEN itself is not considered a druggable target, PTEN synthetic-sick or synthetic-leth...

    Authors: Yew Chung Tang, Szu-Chi Ho, Elisabeth Tan, Alvin Wei Tian Ng, John R. McPherson, Germaine Yen Lin Goh, Bin Tean Teh, Frederic Bard and Steven G. Rozen

    Citation: Breast Cancer Research 2018 20:22

    Published on:

  23. Content type: Research Article

    Breast cancer (BC) is a heterogeneous disease characterised by variant biology and patient outcome. The amino acid transporter, SLC7A5, plays a role in BC although its impact on patient outcome in different BC...

    Authors: Rokaya El Ansari, Madeleine L. Craze, Islam Miligy, Maria Diez-Rodriguez, Christopher C. Nolan, Ian O. Ellis, Emad A. Rakha and Andrew R. Green

    Citation: Breast Cancer Research 2018 20:21

    Published on:

  24. Content type: Research Article

    The Gail model has been widely used and validated with conflicting results. The current study aims to evaluate the performance of different versions of the Gail model by means of systematic review and meta-ana...

    Authors: Xin Wang, Yubei Huang, Lian Li, Hongji Dai, Fengju Song and Kexin Chen

    Citation: Breast Cancer Research 2018 20:18

    Published on:

Page 1 of 180

2016 Journal Metrics