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  1. Content type: Research article

    A large collaborative analysis of data from 47 epidemiological studies concluded that longer duration of breastfeeding reduces the risk of developing breast cancer. Despite the strong epidemiological evidence,...

    Authors: Mustafa M. Basree, Neelam Shinde, Christopher Koivisto, Maria Cuitino, Raleigh Kladney, Jianying Zhang, Julie Stephens, Marilly Palettas, Allen Zhang, Hee Kyung Kim, Santiago Acero-Bedoya, Anthony Trimboli, Daniel G. Stover, Thomas Ludwig, Ramesh Ganju, Daniel Weng…

    Citation: Breast Cancer Research 2019 21:80

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  2. Content type: Research article

    Acquired resistance to trastuzumab is a major clinical problem in the treatment of HER2-positive (HER2+) breast cancer patients. The selection of trastuzumab-resistant patients is a great challenge of precisio...

    Authors: Sònia Palomeras, Ángel Diaz-Lagares, Gemma Viñas, Fernando Setien, Humberto J. Ferreira, Glòria Oliveras, Ana B. Crujeiras, Alejandro Hernández, David H. Lum, Alana L. Welm, Manel Esteller and Teresa Puig

    Citation: Breast Cancer Research 2019 21:79

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  3. Content type: Research article

    The PI3K/AKT pathway is activated through PIK3CA or AKT1 mutations and PTEN loss in breast cancer. We conducted a phase II trial with an allosteric AKT inhibitor MK-2206 in patients with advanced breast cancer...

    Authors: Yan Xing, Nancy U. Lin, Matthew A. Maurer, Huiqin Chen, Armeen Mahvash, Aysegul Sahin, Argun Akcakanat, Yisheng Li, Vandana Abramson, Jennifer Litton, Mariana Chavez-MacGregor, Vicente Valero, Sarina A. Piha-Paul, David Hong, Kim-Anh Do, Emily Tarco…

    Citation: Breast Cancer Research 2019 21:78

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  4. Content type: Research article

    The effective treatment of triple-negative breast cancer (TNBC) remains a profound clinical challenge. Despite frequent epidermal growth factor receptor (EGFR) overexpression and reliance on downstream signall...

    Authors: Ronan P. McLaughlin, Jichao He, Vera E. van der Noord, Jevin Redel, John A. Foekens, John W. M. Martens, Marcel Smid, Yinghui Zhang and Bob van de Water

    Citation: Breast Cancer Research 2019 21:77

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  5. Content type: Research article

    Atypical breast hyperplasias (AH) have a 10-year risk of progression to invasive cancer estimated at 4–7%, with the overall risk of developing breast cancer increased by ~ 4-fold. AH lesions are estrogen recep...

    Authors: Kelly J. Gregory, Amy L. Roberts, Erin M. Conlon, Jacob A. Mayfield, Mary J. Hagen, Giovanna M. Crisi, Brooke A. Bentley, Jeffrey J. Kane, Grace Makari-Judson, Holly S. Mason, Jun Yu, Lihua Julie Zhu, Karl Simin, Jacob P. S. Johnson, Ashraf Khan, Ben R. Schneider…

    Citation: Breast Cancer Research 2019 21:76

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  6. Content type: Research article

    Comprehensive breast cancer risk prediction models enable identifying and targeting women at high-risk, while reducing interventions in those at low-risk. Breast cancer risk prediction models used in clinical ...

    Authors: Chang Ming, Valeria Viassolo, Nicole Probst-Hensch, Pierre O. Chappuis, Ivo D. Dinov and Maria C. Katapodi

    Citation: Breast Cancer Research 2019 21:75

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  7. Content type: Research article

    SHC1 proteins (also called SHCA) exist in three functionally distinct isoforms (p46SHC, p52SHC, and p66SHC) that serve as intracellular adaptors for several key signaling pathways in breast cancer. Despite the...

    Authors: Kevin D. Wright, Bradley S. Miller, Sarah El-Meanawy, Shirng-Wern Tsaih, Anjishnu Banerjee, Aron M. Geurts, Yuri Sheinin, Yunguang Sun, Balaraman Kalyanaraman, Hallgeir Rui, Michael J. Flister and Andrey Sorokin

    Citation: Breast Cancer Research 2019 21:74

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  8. Content type: Research article

    Neoadjuvant chemotherapy is increasingly given preoperatively to shrink breast tumours prior to surgery. This approach also provides the opportunity to study the molecular changes associated with treatment and...

    Authors: Richard J. Bownes, Arran K. Turnbull, Carlos Martinez-Perez, David A. Cameron, Andrew H. Sims and Olga Oikonomidou

    Citation: Breast Cancer Research 2019 21:73

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  9. Content type: Viewpoint

    The companion diagnostic test for checkpoint inhibitor immune therapy is an immunohistochemical test for PD-L1. The test has been shown to be reproducible for expression in tumor cells, but not in immune cells...

    Authors: David L. Rimm, Gang Han, Janis M. Taube, Eunhee S. Yi, Julia A. Bridge, Douglas B. Flieder, Robert Homer, Anja C. Roden, Fred R. Hirsch, Ignacio I. Wistuba and Lajos Pusztai

    Citation: Breast Cancer Research 2019 21:72

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  10. Content type: Short report

    Currently, there is limited data regarding the effectiveness of standard subsequent line therapies such as endocrine therapy, chemotherapy, or targeted agents after progression on CDK4/6 inhibitor-based regime...

    Authors: Lorenzo Rossi, Chiara Biagioni, Amelia McCartney, Ilenia Migliaccio, Giuseppe Curigliano, Giuseppina Sanna, Erica Moretti, Alessandro M. Minisini, Saverio Cinieri, Carlo Tondini, Grazia Arpino, Antonio Bernardo, Angelo Martignetti, Emanuela Risi, Marta Pestrin, Luca Boni…

    Citation: Breast Cancer Research 2019 21:71

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  11. Content type: Research article

    Post-surgery adjuvant radiotherapy (RT) significantly improves clinical outcomes in breast cancer patients; however, some patients develop cancer or treatment-related pain that negatively impacts quality of li...

    Authors: Eunkyung Lee, Omar L. Nelson, Carolina Puyana, Cristiane Takita, Jean L. Wright, Wei Zhao, Isildinha M. Reis, Rick Y. Lin, WayWay M. Hlaing, Johnna L. Bakalar, George R. Yang and Jennifer J. Hu

    Citation: Breast Cancer Research 2019 21:70

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  12. Content type: Research article

    The combined use of a FGFR1 blocker and aromatase inhibitors is appealing for treating breast cancer patients with FGFR1 amplification. However, no pharmacodynamic studies have addressed the effects of this co...

    Authors: Miguel Quintela-Fandino, Juan V. Apala, Diego Malon, Silvana Mouron, Javier Hornedo, Lucia Gonzalez-Cortijo, Ramon Colomer and Juan Guerra

    Citation: Breast Cancer Research 2019 21:69

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  13. Content type: Research article

    Mammographic breast density, adjusted for age and body mass index, and a polygenic risk score (PRS), comprised of common genetic variation, are both strong risk factors for breast cancer and increase discrimin...

    Authors: Celine M. Vachon, Christopher G. Scott, Rulla M. Tamimi, Deborah J. Thompson, Peter A. Fasching, Jennifer Stone, Melissa C. Southey, Stacey Winham, Sara Lindström, Jenna Lilyquist, Graham G. Giles, Roger L. Milne, Robert J. MacInnis, Laura Baglietto, Jingmei Li, Kamila Czene…

    Citation: Breast Cancer Research 2019 21:68

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  14. Content type: Research article

    Breast cancer is the second leading cause of cancer deaths in the USA. Triple-negative breast cancer (TNBC) is a clinically aggressive subtype of breast cancer with high rates of metastasis, tumor recurrence, ...

    Authors: Rachel A. Sabol, Annie C. Bowles, Alex Côté, Rachel Wise, Benjamen O’Donnell, Margarite D. Matossian, Fokhrul M. Hossain, Hope E. Burks, Luis Del Valle, Lucio Miele, Bridgette M. Collins-Burow, Matthew E. Burow and Bruce A. Bunnell

    Citation: Breast Cancer Research 2019 21:67

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  15. Content type: Research article

    Acquirement of resistance is always associated with a highly aggressive phenotype of tumor cells. Recent studies have revealed that Annexin A2 (Anxa2) is a key protein that links drug resistance and cancer met...

    Authors: Yanling Fan, Weiyao Si, Wei Ji, Zhiyong Wang, Zicong Gao, Ran Tian, Weijie Song, He Zhang, Ruifang Niu and Fei Zhang

    Citation: Breast Cancer Research 2019 21:66

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  16. Content type: Research article

    Heterogeneity and lack of targeted therapies represent the two main impediments to precision treatment of triple-negative breast cancer (TNBC), and therefore, molecular subtyping and identification of therapeu...

    Authors: Pascal Jézéquel, Olivier Kerdraon, Hubert Hondermarck, Catherine Guérin-Charbonnel, Hamza Lasla, Wilfried Gouraud, Jean-Luc Canon, Andrea Gombos, Florence Dalenc, Suzette Delaloge, Jérôme Lemonnier, Delphine Loussouarn, Véronique Verrièle and Mario Campone

    Citation: Breast Cancer Research 2019 21:65

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  17. Content type: Research article

    Nicotinamide N-methyltransferase (NNMT) is overexpressed in various human tumors and involved in the development and progression of several carcinomas. In breast cancer, NNMT was found to be overexpressed in seve...

    Authors: Yanzhong Wang, Jin Zeng, Weiping Wu, Shuduo Xie, Haitao Yu, Guoli Li, Tao Zhu, Fengying Li, Jie Lu, Gavin Y. Wang, Xinyou Xie and Jun Zhang

    Citation: Breast Cancer Research 2019 21:64

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  18. Content type: Research article

    HER2-driven breast cancer is correlated with poor prognosis, especially during its later stages. Numerous studies have shown the importance of the integrin α3β1 during the initiation and progression of breast ...

    Authors: Veronika Ramovs, Pablo Secades, Ji-Ying Song, Bram Thijssen, Maaike Kreft and Arnoud Sonnenberg

    Citation: Breast Cancer Research 2019 21:63

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  19. Content type: Research article

    Environmental and genetic factors play an important role in the etiology of breast cancer. Several small blood-based DNA methylation studies have reported risk associations with methylation at individual CpGs ...

    Authors: Clara Bodelon, Srikant Ambatipudi, Pierre-Antoine Dugué, Annelie Johansson, Joshua N. Sampson, Belynda Hicks, Eric Karlins, Amy Hutchinson, Cyrille Cuenin, Veronique Chajès, Melissa C. Southey, Isabelle Romieu, Graham G. Giles, Dallas English, Silvia Polidoro, Manuela Assumma…

    Citation: Breast Cancer Research 2019 21:62

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  20. Content type: Research article

    Glutaminase inhibitors target cancer cells by blocking the conversion of glutamine to glutamate, thereby potentially interfering with anaplerosis and synthesis of amino acids and glutathione. The drug CB-839 h...

    Authors: Maria T. Grinde, Bylgja Hilmarsdottir, Hanna Maja Tunset, Ida Marie Henriksen, Jana Kim, Mads H. Haugen, Morten Beck Rye, Gunhild M. Mælandsmo and Siver A. Moestue

    Citation: Breast Cancer Research 2019 21:61

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  21. Content type: Research article

    The incidence of central nervous system (CNS) metastases in breast cancer patients is rising and has become a major clinical challenge. Only few data are published concerning risk factors for the development o...

    Authors: Elena Laakmann, Isabell Witzel, Peter A. Fasching, Mahdi Rezai, Christian Schem, Christine Solbach, Hans Tesch, Peter Klare, Andreas Schneeweiss, Christoph Salat, Dirk-Michael Zahm, Jens-Uwe Blohmer, Barbara Ingold-Heppner, Jens Huober, Claus Hanusch, Christian Jackisch…

    Citation: Breast Cancer Research 2019 21:60

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  22. Content type: Research article

    Ductal carcinoma in situ (DCIS) is a non-obligate precursor of invasive ductal breast cancer, and approximately 20% of screen-detected tumours are pure DCIS. Most risk factors for breast cancer have similar as...

    Authors: Christos Petridis, Iteeka Arora, Vandna Shah, Anargyros Megalios, Charlotte Moss, Anca Mera, Angela Clifford, Cheryl Gillett, Sarah E. Pinder, Ian Tomlinson, Rebecca Roylance, Michael A. Simpson and Elinor J. Sawyer

    Citation: Breast Cancer Research 2019 21:58

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  23. Content type: Research article

    Women who had children at a young age (less than 25) show a reduced overall risk of breast cancer. However, epidemiological studies showed that for all other women, pregnancy increases the risk of breast cance...

    Authors: Elizabeth Slocum, Amanda Craig, Augusto Villanueva and Doris Germain

    Citation: Breast Cancer Research 2019 21:56

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  24. Content type: Research article

    The role of the BARD1 gene in breast cancer (BC) and ovarian cancer (OC) predisposition remains elusive, as published case-control investigations have revealed controversial results. We aimed to assess the role o...

    Authors: Nana Weber-Lassalle, Julika Borde, Konstantin Weber-Lassalle, Judit Horváth, Dieter Niederacher, Norbert Arnold, Silke Kaulfuß, Corinna Ernst, Victoria G. Paul, Ellen Honisch, Kristina Klaschik, Alexander E. Volk, Christian Kubisch, Steffen Rapp, Nadine Lichey, Janine Altmüller…

    Citation: Breast Cancer Research 2019 21:55

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  25. Content type: Research article

    Highly aggressive, metastatic and therapeutically resistant triple-negative breast cancers (TNBCs) are often enriched for cancer stem cells (CSC). Cytokines within the breast tumor microenvironment (TME) influ...

    Authors: Mary R. Doherty, Jenny G. Parvani, Ilaria Tamagno, Damian J. Junk, Benjamin L. Bryson, Hyeon Joo Cheon, George R. Stark and Mark W. Jackson

    Citation: Breast Cancer Research 2019 21:54

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  26. Content type: Research article

    To evaluate the cross-talk between BRCA1-IRIS (IRIS)-overexpressing (IRISOE) TNBC cells and tumor-resident mesenchymal stem cells (MSCs) that triggers the aggressiveness or elimination of IRISOE TNBC tumors.

    Authors: Daniel Ryan, Bibbin T. Paul, Jim Koziol and Wael M. ElShamy

    Citation: Breast Cancer Research 2019 21:53

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  27. Content type: Research article

    The use of aspirin and other non-steroidal anti-inflammatory drugs (NSAIDs) has been associated with reduced breast cancer risk, but it is not known if this association extends to women at familial or genetic ...

    Authors: Rebecca D. Kehm, John L. Hopper, Esther M. John, Kelly-Anne Phillips, Robert J. MacInnis, Gillian S. Dite, Roger L. Milne, Yuyan Liao, Nur Zeinomar, Julia A. Knight, Melissa C. Southey, Linda Vahdat, Naomi Kornhauser, Tessa Cigler, Wendy K. Chung, Graham G. Giles…

    Citation: Breast Cancer Research 2019 21:52

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  28. Content type: Research article

    BRCA1-associated breast cancer originates from luminal progenitor cells. BRCA1 functions in multiple biological processes, including double-strand break repair, replication stress suppression, transcriptional reg...

    Authors: Xiaowen Zhang, Yao Wang, Huai-Chin Chiang, Yuan-Pang Hsieh, Chang Lu, Ben Ho Park, Ismail Jatoi, Victor X. Jin, Yanfen Hu and Rong Li

    Citation: Breast Cancer Research 2019 21:51

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  29. Content type: Research article

    Telomeres and telomerase play key roles in the chromosomal maintenance and stability. Recent epidemiological studies have shown that longer telomeres are associated with increased risk of several cancer types....

    Authors: Hamed Samavat, Xiaoshuang Xun, Aizhen Jin, Renwei Wang, Woon-Puay Koh and Jian-Min Yuan

    Citation: Breast Cancer Research 2019 21:50

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  30. Content type: Research article

    Obesity and elevated breast density are common risk factors for breast cancer, and their effects may vary by estrogen receptor (ER) subtype. However, their joint effects on ER subtype-specific risk are unknown...

    Authors: Yiwey Shieh, Christopher G. Scott, Matthew R. Jensen, Aaron D. Norman, Kimberly A. Bertrand, V. Shane Pankratz, Kathleen R. Brandt, Daniel W. Visscher, John A. Shepherd, Rulla M. Tamimi, Celine M. Vachon and Karla Kerlikowske

    Citation: Breast Cancer Research 2019 21:48

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  31. Content type: Research article

    Our previous genome-wide association study using the MA.27 aromatase inhibitors adjuvant trial identified SNPs in the long noncoding RNA MIR2052HG associated with breast cancer-free interval. MIR2052HG maintained...

    Authors: Junmei Cairns, James N. Ingle, Krishna R. Kalari, Lois E. Shepherd, Michiaki Kubo, Matthew P. Goetz, Richard M. Weinshilboum and Liewei Wang

    Citation: Breast Cancer Research 2019 21:47

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  32. Content type: Research article

    Full-term pregnancy (FTP) at an early age confers long-term protection against breast cancer. Previously, we reported that a FTP imprints a specific gene expression profile in the breast of postmenopausal wome...

    Authors: Julia Santucci-Pereira, Anne Zeleniuch-Jacquotte, Yelena Afanasyeva, Hua Zhong, Michael Slifker, Suraj Peri, Eric A. Ross, Ricardo López de Cicco, Yubo Zhai, Theresa Nguyen, Fathima Sheriff, Irma H. Russo, Yanrong Su, Alan A. Arslan, Pal Bordas, Per Lenner…

    Citation: Breast Cancer Research 2019 21:46

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  33. Content type: Correction

    After the publication of this work [1] errors were found in Figs. 1a and 5d.

    Authors: Kyung-min Lee, Keesoo Nam, Sunhwa Oh, Juyeon Lim, Young-Pil Kim, Jong Won Lee, Jong-Han Yu, Sei-Hyun Ahn, Sung-Bae Kim, Dong-Young Noh, Taehoon Lee and Incheol Shin

    Citation: Breast Cancer Research 2019 21:45

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    The original article was published in Breast Cancer Research 2014 16:479

  34. Content type: Research article

    Hypothyroidism may occur as a late effect of breast cancer-directed treatment, particularly after radiotherapy, but little is known whether hypothyroidism affects the prognosis after breast cancer. We investig...

    Authors: Anne Mette Falstie-Jensen, Anders Kjærsgaard, Ebbe Laugaard Lorenzen, Jeanette Dupont Jensen, Kristin Valborg Reinertsen, Olaf M. Dekkers, Marianne Ewertz and Deirdre P. Cronin-Fenton

    Citation: Breast Cancer Research 2019 21:44

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  35. Content type: Research article

    The oncogenic receptor tyrosine kinase (RTK) ERBB2 is known to dimerize with other EGFR family members, particularly ERBB3, through which it potently activates PI3K signalling. Antibody-mediated inhibition of ...

    Authors: Sean P. Kennedy, Jeremy Z. R. Han, Neil Portman, Max Nobis, Jordan F. Hastings, Kendelle J. Murphy, Sharissa L. Latham, Antonia L. Cadell, Dushan Miladinovic, Gabriella R. Marriott, Yolande E. I. O’Donnell, Robert F. Shearer, James T. Williams, Amaya Garcia Munoz, Thomas R. Cox, D. Neil Watkins…

    Citation: Breast Cancer Research 2019 21:43

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  36. Content type: Research article

    Models that accurately predict risk of breast cancer are needed to help younger women make decisions about when to begin screening. Premenopausal concentrations of circulating anti-Müllerian hormone (AMH), a b...

    Authors: Tess V. Clendenen, Wenzhen Ge, Karen L. Koenig, Yelena Afanasyeva, Claudia Agnoli, Louise A. Brinton, Farbod Darvishian, Joanne F. Dorgan, A. Heather Eliassen, Roni T. Falk, Göran Hallmans, Susan E. Hankinson, Judith Hoffman-Bolton, Timothy J. Key, Vittorio Krogh, Hazel B. Nichols…

    Citation: Breast Cancer Research 2019 21:42

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  37. Content type: Research article

    Obesity is associated with an increased risk of breast cancer recurrence and cancer death. Recurrent cancers arise from the pool of residual tumor cells, or minimal residual disease (MRD), that survives primar...

    Authors: Brett L. Ecker, Jun Y. Lee, Christopher J. Sterner, Aaron C. Solomon, Dhruv K. Pant, Fei Shen, Javier Peraza, Lauren Vaught, Samyukta Mahendra, George K. Belka, Tien-chi Pan, Kathryn H. Schmitz and Lewis A. Chodosh

    Citation: Breast Cancer Research 2019 21:41

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  38. Content type: Research article

    Epidemiologic data suggest that parity increases risk of hormone receptor-negative breast cancer and that breastfeeding attenuates this association. Prospective data, particularly on the joint effects of highe...

    Authors: Renée T. Fortner, Julia Sisti, Boyang Chai, Laura C. Collins, Bernard Rosner, Susan E. Hankinson, Rulla M. Tamimi and A. Heather Eliassen

    Citation: Breast Cancer Research 2019 21:40

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  39. Content type: Research article

    Neratinib is an irreversible pan-HER tyrosine kinase inhibitor that inhibits PI3K/Akt and MAPK signaling pathways after HER2 receptor activation. The ExteNET study showed that neratinib significantly improved ...

    Authors: Stephen K. L. Chia, Miguel Martin, Frankie A. Holmes, Bent Ejlertsen, Suzette Delaloge, Beverly Moy, Hiroji Iwata, Gunter von Minckwitz, Janine Mansi, Carlos H. Barrios, Michael Gnant, Zorica Tomašević, Neelima Denduluri, Robert Šeparović, Sung-Bae Kim, Erik Hugger Jakobsen…

    Citation: Breast Cancer Research 2019 21:39

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  40. Content type: Research article

    High background parenchymal uptake (BPU) on molecular breast imaging (MBI) has been identified as a breast cancer risk factor. We explored the feasibility of offering a short-term intervention of low-dose oral...

    Authors: Carrie B. Hruska, Katie N. Hunt, Amy Lynn Conners, Jennifer R. Geske, Kathleen R. Brandt, Amy C. Degnim, Celine M. Vachon, Michael K. O’Connor and Deborah J. Rhodes

    Citation: Breast Cancer Research 2019 21:38

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  41. Content type: Research article

    Triple-negative breast cancers (TNBCs), which lack receptors for estrogen, progesterone, and amplification of epidermal growth factor receptor 2, are highly aggressive. Consequently, patients diagnosed with TN...

    Authors: Geraldine Vidhya Vijay, Na Zhao, Petra Den Hollander, Mike J. Toneff, Robiya Joseph, Mika Pietila, Joseph H. Taube, Tapasree R. Sarkar, Esmeralda Ramirez-Pena, Steven J. Werden, Maryam Shariati, Ruli Gao, Mary Sobieski, Clifford C. Stephan, Nathalie Sphyris, Noayuki Miura…

    Citation: Breast Cancer Research 2019 21:37

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  42. Content type: Research article

    The seed and soil hypothesis was proposed over a century ago to describe why cancer cells (seeds) grow in certain organs (soil). Since then, the genetic properties that define the cancer cells have been heavil...

    Authors: Mohammad A. Alzubi, Tia H. Turner, Amy L. Olex, Sahib S. Sohal, Nicholas P. Tobin, Susana G. Recio, Jonas Bergh, Thomas Hatschek, Joel S. Parker, Carol A. Sartorius, Charles M. Perou, Mikhail G. Dozmorov and J. Chuck Harrell

    Citation: Breast Cancer Research 2019 21:36

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  43. Content type: Review

    Breast cancer is the second most common cause of cancer-related death among women. Advances in our understanding of the disease have translated into better diagnostics and more effective therapeutics, leading ...

    Authors: Laura Garcia-Estevez and Gema Moreno-Bueno

    Citation: Breast Cancer Research 2019 21:35

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  44. Content type: Research article

    Use of cyclin D1 (CCND1) gene amplification as a breast cancer biomarker has been hampered by conflicting assessments of the relationship between cyclin D1 protein levels and patient survival. Here, we aimed to c...

    Authors: Arian Lundberg, Linda S. Lindström, Jingmei Li, J. Chuck Harrell, Eva Darai-Ramqvist, Emmanouil G. Sifakis, Theodoros Foukakis, Charles M. Perou, Kamila Czene, Jonas Bergh and Nicholas P. Tobin

    Citation: Breast Cancer Research 2019 21:34

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  45. Content type: Research article

    Mammographic density (MD) is an established risk factor for breast cancer. There are significant ethnic differences in MD measures which are consistent with those for corresponding breast cancer risk. This is ...

    Authors: Kirsty McLean, Ellie Darcey, Gemma Cadby, Helen Lund, Leanne Pilkington, Andrew Redfern, Sandra Thompson, Christobel Saunders, Elizabeth Wylie and Jennifer Stone

    Citation: Breast Cancer Research 2019 21:33

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  46. Content type: Research article

    We characterized patterns of occurrence and the impact of neratinib-associated diarrhea in the absence of protocol-directed antidiarrheal prophylaxis or a formal diarrhea management plan using data from Extend...

    Authors: Joanne Mortimer, Jack Di Palma, Kendra Schmid, Yining Ye and Mohammad Jahanzeb

    Citation: Breast Cancer Research 2019 21:32

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  47. Content type: Research article

    In a cancer-free environment in the adult, the skeleton continuously undergoes remodeling. Bone-resorbing osteoclasts excavate erosion cavities, and bone-depositing osteoblasts synthesize osteoid matrix that f...

    Authors: Alexus D. Kolb, Alison B. Shupp, Dimpi Mukhopadhyay, Frank C. Marini and Karen M. Bussard

    Citation: Breast Cancer Research 2019 21:31

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