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  1. Content type: Review

    Differentiation of stem cells into highly specialised cells requires gene expression changes brought about by remodelling of the chromatin architecture. During this lineage-commitment process, the majority of ...

    Authors: Holly Holliday, Laura A. Baker, Simon R. Junankar, Susan J. Clark and Alexander Swarbrick

    Citation: Breast Cancer Research 2018 20:100

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  2. Content type: Research article

    While many studies have shown that maternal factors in pregnancy affect the cancer risk for offspring, few studies have investigated the impact of paternal exposures on their progeny’s risk of this disease. Po...

    Authors: Raquel Santana da Cruz, Elissa J. Carney, Johan Clarke, Hong Cao, M. Idalia Cruz, Carlos Benitez, Lu Jin, Yi Fu, Zuolin Cheng, Yue Wang and Sonia de Assis

    Citation: Breast Cancer Research 2018 20:99

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  3. Content type: Correction

    After the publication of this work [1], an error was noticed in Fig. 2b and Fig. 4b as well as Fig. 4b. and Fig. 5d. Images of the ERK1/2 blots were accidentally duplicated. In Fig. 5a. and Fig. 5c., the last ...

    Authors: Iain R. Hutcheson, Janice M. Knowlden, Steve E. Hiscox, Denise Barrow, Julia M. W. Gee, John F. Robertson, Ian O. Ellis and Robert I. Nicholson

    Citation: Breast Cancer Research 2018 20:98

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    The original article was published in Breast Cancer Research 2007 9:R50

  4. Content type: Research article

    Although ductal carcinoma in situ (DCIS) is a non-invasive breast cancer, many DCIS lesions may progress to invasive cancer and the genes and pathways responsible for its progression are largely unknown. FGFR1...

    Authors: Mao Yang, Xiaobin Yu, Xuesen Li, Bo Luo, Wenli Yang, Yan Lin, Dabing Li, Zhonglin Gan, Jianming Xu and Tao He

    Citation: Breast Cancer Research 2018 20:97

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  5. Content type: Research article

    Long-term insulin exposure has been implicated in breast cancer etiology, but epidemiological evidence remains inconclusive. The aims of this study were to investigate the association of insulin therapy with m...

    Authors: Signe Borgquist, Ann H. Rosendahl, Kamila Czene, Nirmala Bhoo-Pathy, Mozhgan Dorkhan, Per Hall and Judith S. Brand

    Citation: Breast Cancer Research 2018 20:93

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  6. Content type: Research article

    Molecular classification of tumour clonality is currently not evaluated in multiple invasive breast carcinomas, despite evidence suggesting common clonal origins. There is no consensus about which type of data...

    Authors: Jana Biermann, Toshima Z. Parris, Szilárd Nemes, Anna Danielsson, Hanna Engqvist, Elisabeth Werner Rönnerman, Eva Forssell-Aronsson, Anikó Kovács, Per Karlsson and Khalil Helou

    Citation: Breast Cancer Research 2018 20:96

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  7. Content type: Research article

    Epidemiological studies have consistently shown that increased mammographic density (MD) is a strong risk factor for breast cancer. We previously observed an elevated number of vimentin+/CD45+ leukocytes in high ...

    Authors: Cecilia W. Huo, Prue Hill, Grace Chew, Paul J. Neeson, Heloise Halse, Elizabeth D. Williams, Michael A. Henderson, Erik W. Thompson and Kara L. Britt

    Citation: Breast Cancer Research 2018 20:92

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  8. Content type: Research article

    Upregulation of human epidermal growth factor receptor 3 (HER3) is a major mechanism of acquired resistance to therapies targeting its heterodimerization partners epidermal growth factor receptor (EGFR) and hu...

    Authors: Takuya Osada, Zachary C. Hartman, Junping Wei, Gangjun Lei, Amy C. Hobeika, William R. Gwin, Marcio A. Diniz, Neil Spector, Timothy M. Clay, Wei Chen, Michael A. Morse and H. Kim Lyerly

    Citation: Breast Cancer Research 2018 20:90

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  9. Content type: Research article

    Thyroxine (T4) has been positively associated with tumor cell proliferation, while the effect of triiodothyronine (T3) on cell proliferation has not been well-established because it differs according to the ty...

    Authors: Carolina Ortega-Olvera, Alfredo Ulloa-Aguirre, Angélica Ángeles-Llerenas, Fernando Enrique Mainero-Ratchelous, Claudia Elena González-Acevedo, Ma. de Lourdes Hernández-Blanco, Elad Ziv, Larissa Avilés-Santa, Edelmiro Pérez-Rodríguez and Gabriela Torres-Mejía

    Citation: Breast Cancer Research 2018 20:94

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  10. Content type: Research article

    We evaluated the association between volumetric breast density (BD) and risk of advanced cancers after a negative screening episode.

    Authors: Donella Puliti, Marco Zappa, Paolo Giorgi Rossi, Elena Pierpaoli, Gianfranco Manneschi, Daniela Ambrogetti, Leonardo Ventura and Paola Mantellini

    Citation: Breast Cancer Research 2018 20:95

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  11. Content type: Research article

    Fibroadenomas are common benign breast lesions, and studies of European American women indicate a persistent, increased risk of breast cancer after diagnosing a fibroadenoma on biopsy. This association has not...

    Authors: Asra N. Shaik, Julie J. Ruterbusch, Eman Abdulfatah, Resha Shrestha, M. H. D. Fayez Daaboul, Visakha Pardeshi, Daniel W. Visscher, Sudeshna Bandyopadhyay, Rouba Ali-Fehmi and Michele L. Cote

    Citation: Breast Cancer Research 2018 20:91

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  12. Content type: Correction

    After the publication of this work [1], an error was noticed in Fig. 4a. The micrograph image sh528 was accidentally duplicated.

    Authors: Benjamin A. Katchman, I. Tolgay Ocal, Heather E. Cunliffe, Yu-Hui Chang, Galen Hostetter, Aprill Watanabe, Janine LoBello and Douglas F. Lake

    Citation: Breast Cancer Research 2018 20:89

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    The original article was published in Breast Cancer Research 2013 15:R28

  13. Content type: Research article

    Inflammatory breast cancer (IBC) is the most aggressive form of primary breast cancer. Using a custom-made breast cancer gene sequencing panel, we investigated somatic mutations in IBC to better understand the...

    Authors: Xu Liang, Sophie Vacher, Anais Boulai, Virginie Bernard, Sylvain Baulande, Mylene Bohec, Ivan Bièche, Florence Lerebours and Céline Callens

    Citation: Breast Cancer Research 2018 20:88

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  14. Content type: Research article

    Breast cancer is the most prevalent tumor entity in Li-Fraumeni syndrome. Up to 80% of individuals with a Li-Fraumeni-like phenotype do not harbor detectable causative germline TP53 variants. Yet, no systematic p...

    Authors: Judith Penkert, Gunnar Schmidt, Winfried Hofmann, Stephanie Schubert, Maximilian Schieck, Bernd Auber, Tim Ripperger, Karl Hackmann, Marc Sturm, Holger Prokisch, Ursula Hille-Betz, Dorothea Mark, Thomas Illig, Brigitte Schlegelberger and Doris Steinemann

    Citation: Breast Cancer Research 2018 20:87

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  15. Content type: Research article

    Mesenchymal transformation of pulmonary endothelial cells contributes to the formation of a metastatic microenvironment, but it is not known whether this precedes or follows early metastasis formation. In the ...

    Authors: Marta Smeda, Anna Kieronska, Mateusz G. Adamski, Bartosz Proniewski, Magdalena Sternak, Tasnim Mohaissen, Kamil Przyborowski, Katarzyna Derszniak, Dawid Kaczor, Marta Stojak, Elzbieta Buczek, Agnieszka Jasztal, Joanna Wietrzyk and Stefan Chlopicki

    Citation: Breast Cancer Research 2018 20:86

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  16. Content type: Research article

    Breast magnetic resonance imaging (MRI) is the most sensitive imaging method for breast cancer detection and is therefore offered as a screening technique to women at increased risk of developing breast cancer...

    Authors: Suzan Vreemann, Jan C. M. van Zelst, Margrethe Schlooz-Vries, Peter Bult, Nicoline Hoogerbrugge, Nico Karssemeijer, Albert Gubern-Mérida and Ritse M. Mann

    Citation: Breast Cancer Research 2018 20:84

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  17. Content type: Review

    Physical inactivity and being overweight are modifiable lifestyle risk factors that consistently have been associated with a higher risk of postmenopausal breast cancer in observational studies. One biologic h...

    Authors: Martijn de Roon, Anne M. May, Anne McTiernan, Rob J. P. M. Scholten, Petra H. M. Peeters, Christine M. Friedenreich and Evelyn M. Monninkhof

    Citation: Breast Cancer Research 2018 20:81

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  18. Content type: Research article

    Although numerous studies have reported that tricho-rhino-phalangeal syndrome type I (TRPS1) protein, the only reported atypical GATA transcription factor, is overexpressed in various carcinomas, the underlyin...

    Authors: Yuzhi Wang, Jun Zhang, Lele Wu, Weiguang Liu, Guanyun Wei, Xue Gong, Yan Liu, Zhifang Ma, Fei Ma, Jean Paul Thiery and Liming Chen

    Citation: Breast Cancer Research 2018 20:83

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  19. Content type: Research article

    Triple-negative breast cancer (TNBC) remains an aggressive breast cancer subtype with limited treatment options. ENMD-2076 is a small-molecule inhibitor of Aurora and angiogenic kinases with proapoptotic and a...

    Authors: Jennifer R. Diamond, S. G. Eckhardt, Todd M. Pitts, Adrie van Bokhoven, Dara Aisner, Daniel L. Gustafson, Anna Capasso, Sharon Sams, Peter Kabos, Kathryn Zolman, Tiffany Colvin, Anthony D. Elias, Anna M. Storniolo, Bryan P. Schneider, Dexiang Gao, John J. Tentler…

    Citation: Breast Cancer Research 2018 20:82

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  20. Content type: Correction

    After the publication of this work [1] an error was noticed in Fig. 6 (b). In the MCF-7/Vector columns, the same image was used accidentally for the 0 h and 24 h time points. Both images were taken from the 0 ...

    Authors: David S. Guttery, Rachael A. Hancox, Kellie T. Mulligan, Simon Hughes, Sinead M. Lambe, J. Howard Pringle, Rosemary A. Walker, J. Louise Jones and Jacqueline A. Shaw

    Citation: Breast Cancer Research 2018 20:80

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    The original article was published in Breast Cancer Research 2010 12:R57

  21. Content type: Research article

    The PAM50-based (Prosigna) risk of recurrence (ROR) score and intrinsic subtypes are prognostic for women with high-risk breast cancer. We investigate the predictive ability of Prosigna regarding the effective...

    Authors: Maj-Britt Jensen, Anne-Vibeke Lænkholm, Torsten O. Nielsen, Jens Ole Eriksen, Pernille Wehn, Tressa Hood, Namratha Ram, Wesley Buckingham, Sean Ferree and Bent Ejlertsen

    Citation: Breast Cancer Research 2018 20:79

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  22. Content type: Research article

    Hypoxia is a key driver of cancer progression. We evaluated the prognostic impact of 18F-fluoromisonidazole (FMISO) prior to treatment in patients with breast cancer.

    Authors: Aya Asano, Shigeto Ueda, Ichiei Kuji, Tomohiko Yamane, Hideki Takeuchi, Eiko Hirokawa, Ikuko Sugitani, Hiroko Shimada, Takahiro Hasebe, Akihiko Osaki and Toshiaki Saeki

    Citation: Breast Cancer Research 2018 20:78

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    The Correction to this article has been published in Breast Cancer Research 2018 20:107

  23. Content type: Retraction Note

    The authors are retracting this article [1] after an investigation by the Ethics Committee of the Fourth Military Medical University (Xi’an, Shaanxi, China) of the following concerns that had been raised with ...

    Authors: Jun-Tang Li, Li-Feng Wang, Ya-Li Zhao, Tao Yang, Wei Li, Jing Zhao, Feng Yu, Lei Wang, Yan-Ling Meng, Ning-Ning Liu, Xiao-Shan Zhu, Chun-Fang Gao, Lin-Tao Jia and An-Gang Yang

    Citation: Breast Cancer Research 2018 20:77

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    The original article was published in Breast Cancer Research 2014 16:454

  24. Content type: Research article

    Overcoming systemic dormancy and initiating secondary tumor grow under unique microenvironmental conditions is a major rate-limiting step in metastatic progression. Disseminated tumor cells encounter major cha...

    Authors: Aparna Shinde, Tomasz Wilmanski, Hao Chen, Dorothy Teegarden and Michael K. Wendt

    Citation: Breast Cancer Research 2018 20:76

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  25. Content type: Research article

    Estrogen promotes breast cancer development and progression mainly through estrogen receptor (ER). However, blockage of estrogen production or action prevents development of and suppresses progression of ER-ne...

    Authors: Chuying Wang, Feng Bai, Li-han Zhang, Alexandria Scott, Enxiao Li and Xin-Hai Pei

    Citation: Breast Cancer Research 2018 20:74

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  26. Content type: Research article

    In primary breast cancer metastases frequently arise from a state of dormancy that may persist for extended periods of time. We investigated the efficacy of plasma micro-RNA (miR)-21, miR-23b, miR-190, miR-200...

    Authors: Chara Papadaki, Michalis Stratigos, Georgios Markakis, Maria Spiliotaki, Georgios Mastrostamatis, Christoforos Nikolaou, Dimitrios Mavroudis and Sofia Agelaki

    Citation: Breast Cancer Research 2018 20:72

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  27. Content type: Research article

    The ETS transcription factor ETV4 is involved in the main steps of organogenesis and is also a significant mediator of tumorigenesis and metastasis, such as in breast cancer. Indeed, ETV4 is overexpressed in b...

    Authors: Mandy Dumortier, Franck Ladam, Isabelle Damour, Sophie Vacher, Ivan Bièche, Nathalie Marchand, Yvan de Launoit, David Tulasne and Anne Chotteau-Lelièvre

    Citation: Breast Cancer Research 2018 20:73

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  28. Content type: Research article

    Vitamin D has anticarcinogenic and immune-related properties and may protect against some diseases, including breast cancer. Vitamin D affects gene transcription and may influence DNA methylation.

    Authors: Katie M. O’Brien, Dale P. Sandler, Zongli Xu, H. Karimi Kinyamu, Jack A. Taylor and Clarice R. Weinberg

    Citation: Breast Cancer Research 2018 20:70

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  29. Content type: Research article

    Elevated PD-L1 expression on tumor cells, a context associated with an adaptive immune response, has been linked to the total burden of copy number variants (CNVs) in aneuploid tumors, to microsatellite instab...

    Authors: Michael T. Barrett, Elizabeth Lenkiewicz, Smriti Malasi, Anamika Basu, Jennifer Holmes Yearley, Lakshmanan Annamalai, Ann E. McCullough, Heidi E. Kosiorek, Pooja Narang, Melissa A. Wilson Sayres, Meixuan Chen, Karen S. Anderson and Barbara A. Pockaj

    Citation: Breast Cancer Research 2018 20:71

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  30. Content type: Short report

    The 2013 update of the American Society of Clinical Oncology-College of American Pathologists (ASCO-CAP) human epidermal growth factor receptor 2 (HER2) testing guidelines recommend using an alternative chromo...

    Authors: Neelam V. Desai, Vanda Torous, Joel Parker, James T. Auman, Gary B. Rosson, Cassandra Cruz, Charles M. Perou, Stuart J. Schnitt and Nadine Tung

    Citation: Breast Cancer Research 2018 20:75

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  31. Content type: Research article

    In over 20% of breast conserving operations, postoperative pathological assessment of the excised tissue reveals positive margins, requiring additional surgery. Current techniques for intra-operative assessmen...

    Authors: Dustin W. Shipp, Emad A. Rakha, Alexey A. Koloydenko, R. Douglas Macmillan, Ian O. Ellis and Ioan Notingher

    Citation: Breast Cancer Research 2018 20:69

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    The Editorial to this article has been published in Breast Cancer Research 2018 20:85

  32. Content type: Correction

    After the publication of this work [1], an error was noticed in Fig. 2b, Fig. 3a and Fig. 5b. The Skp1 loading control was accidentally duplicated. We apologize for this error, which did not affect any of the ...

    Authors: Ma’anit Shapira, Eli Kakiashvili, Tzur Rosenberg and Dan D. Hershko

    Citation: Breast Cancer Research 2018 20:68

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    The original article was published in Breast Cancer Research 2006 8:R46

  33. Content type: Research article

    Syndecan-1 (Sdc1), a cell surface heparan sulfate proteoglycan normally expressed primarily by epithelia and plasma cells, is aberrantly induced in stromal fibroblasts of breast carcinomas. Stromal fibroblast-...

    Authors: Colleen Chute, Xinhai Yang, Kristy Meyer, Ning Yang, Keelin O’Neil, Ildiko Kasza, Kevin Eliceiri, Caroline Alexander and Andreas Friedl

    Citation: Breast Cancer Research 2018 20:66

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  34. Content type: Research article

    Circulating tumor cells (CTCs) are the major players in the metastatic process. A potential mechanism of cell migration and invasion is the formation of microtentacles in tumor cells. These structures are supp...

    Authors: G. Kallergi, D. Aggouraki, N. Zacharopoulou, C. Stournaras, V. Georgoulias and S. S. Martin

    Citation: Breast Cancer Research 2018 20:67

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  35. Content type: Research article

    Adjuvant radiotherapy is the standard of care after breast-conserving surgery for primary breast cancer, despite a majority of patients being over- or under-treated. In contrast to adjuvant endocrine therapy a...

    Authors: Martin Sjöström, Johan Staaf, Patrik Edén, Fredrik Wärnberg, Jonas Bergh, Per Malmström, Mårten Fernö, Emma Niméus and Irma Fredriksson

    Citation: Breast Cancer Research 2018 20:64

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  36. Content type: Research article

    The microenvironment and stress factors like glucocorticoids have a strong influence on breast cancer progression but their role in the first stages of breast cancer and, particularly, in myoepithelial cell re...

    Authors: Arantzazu Zubeldia-Plazaola, Leire Recalde-Percaz, Núria Moragas, Mireia Alcaraz, Xieng Chen, Mario Mancino, Patricia Fernández-Nogueira, Miquel Prats de Puig, Flavia Guzman, Aleix Noguera-Castells, Anna López-Plana, Estel Enreig, Neus Carbó, Vanessa Almendro, Pedro Gascón, Paloma Bragado…

    Citation: Breast Cancer Research 2018 20:65

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  37. Content type: Correction

    After the publication of this work [1] an error in Fig. 1c was brought to our attention: the Western blots for PRDX6 and β-actin were similar to those shown in lanes 5-6 of Fig. 4g. To verify these findings, w...

    Authors: Xin-Zhong Chang, Da-Qiang Li, Yi-Feng Hou, Jiong Wu, Jin-Song Lu, Gen-Hong Di, Wei Jin, Zhou-Luo Ou, Zhen-Zhou Shen and Zhi-Ming Shao

    Citation: Breast Cancer Research 2018 20:63

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    The original article was published in Breast Cancer Research 2007 9:R76

  38. Content type: Research article

    Tumor-infiltrating lymphocytes (TILs) evaluated in primary breast cancer (BC) convey prognostic information. Limited data in the metastatic setting are available.

    Authors: Maria Vittoria Dieci, Vassilena Tsvetkova, Enrico Orvieto, Federico Piacentini, Guido Ficarra, Gaia Griguolo, Federica Miglietta, Tommaso Giarratano, Claudia Omarini, Serena Bonaguro, Rocco Cappellesso, Camillo Aliberti, Grazia Vernaci, Carlo Alberto Giorgi, Giovanni Faggioni, Giulia Tasca…

    Citation: Breast Cancer Research 2018 20:62

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  39. Content type: Correction

    After the publication of this work [1] errors were noticed in the total protein loading controls for Figs. 1C, 2B, 3B and 4B.

    Authors: Kheng Tian Lim, Niamh Cosgrave, Arnold David Hill and Leonie S. Young

    Citation: Breast Cancer Research 2018 20:61

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    The original article was published in Breast Cancer Research 2006 8:R33

  40. Content type: Research article

    As crucial regulators of the immune response against pathogens, macrophages have been extensively shown also to be important players in several diseases, including cancer. Specifically, breast cancer macrophag...

    Authors: Sara Donzelli, Elisa Milano, Magdalena Pruszko, Andrea Sacconi, Silvia Masciarelli, Ilaria Iosue, Elisa Melucci, Enzo Gallo, Irene Terrenato, Marcella Mottolese, Maciej Zylicz, Alicja Zylicz, Francesco Fazi, Giovanni Blandino and Giulia Fontemaggi

    Citation: Breast Cancer Research 2018 20:59

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  41. Content type: Research article

    Endocrine resistance in estrogen receptor-positive (ER+) breast cancer is a major clinical problem and is associated with accelerated cancer cell growth, increased motility and acquisition of mesenchymal chara...

    Authors: Carla L. Alves, Daniel Elias, Maria B. Lyng, Martin Bak and Henrik J. Ditzel

    Citation: Breast Cancer Research 2018 20:60

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  42. Content type: Research article

    Numerous studies have analyzed associations between apparent diffusion coefficient (ADC) and histopathological features such as Ki-67 proliferation index in breast cancer (BC), with mixed results. The purpose ...

    Authors: Alexey Surov, Paola Clauser, Yun-Woo Chang, Lihua Li, Laura Martincich, Savannah C. Partridge, Jin You Kim, Hans Jonas Meyer and Andreas Wienke

    Citation: Breast Cancer Research 2018 20:58

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  43. Content type: Research article

    Resected HER2 breast cancer patients treated with adjuvant trastuzumab and chemotherapy have superior survival compared to patients treated with chemotherapy alone. We previously showed that trastuzumab and ch...

    Authors: Nadine Norton, Nicholas Fox, Christie-Ann McCarl, Kathleen S. Tenner, Karla Ballman, Courtney L. Erskine, Brian M. Necela, Donald Northfelt, Winston W. Tan, Carmen Calfa, Mark Pegram, Gerardo Colon-Otero, Edith A. Perez, Raphael Clynes and Keith L. Knutson

    Citation: Breast Cancer Research 2018 20:52

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  44. Content type: Research article

    Altered lipid metabolism is an emerging hallmark of aggressive breast cancers. The N-myc downstream regulated gene (NDRG1) gene plays a critical role in peripheral nervous system myelination, as inactivating m...

    Authors: Christopher J. Sevinsky, Faiza Khan, Leila Kokabee, Anza Darehshouri, Krishna Rao Maddipati and Douglas S. Conklin

    Citation: Breast Cancer Research 2018 20:55

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  45. Content type: Research article

    The purpose of this work was to investigate noninvasive early detection of treatment response of breast cancer patients to neoadjuvant chemotherapy (NAC) using chemical exchange saturation transfer (CEST) meas...

    Authors: Erwin Krikken, Vitaliy Khlebnikov, Moritz Zaiss, Rajni A. Jibodh, Paul J. van Diest, Peter R. Luijten, Dennis W. J. Klomp, Hanneke W. M. van Laarhoven and Jannie P. Wijnen

    Citation: Breast Cancer Research 2018 20:51

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  46. Content type: Research article

    Breast cancer pathologic complete response (pCR) to neoadjuvant chemotherapy (NAC) varies with tumor subtype. The purpose of this study was to identify an early treatment window for predicting pCR based on tum...

    Authors: Quing Zhu, Susan Tannenbaum, Scott H. Kurtzman, Patricia DeFusco, Andrew Ricci Jr, Hamed Vavadi, Feifei Zhou, Chen Xu, Alex Merkulov, Poornima Hegde, Mark Kane, Liqun Wang and Kert Sabbath

    Citation: Breast Cancer Research 2018 20:56

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  47. Content type: Research article

    Metastatic triple-negative breast cancer (TNBC) is a heterogeneous and incurable disease. Numerous studies have been conducted to seek molecular targets to treat TNBC effectively, but chemotherapy is still the...

    Authors: Kideok Jin, Niranjan B. Pandey and Aleksander S. Popel

    Citation: Breast Cancer Research 2018 20:54

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  48. Content type: Research article

    Obesity and type II diabetes are linked to increased breast cancer risk in postmenopausal women. Patients treated with the antidiabetic drug metformin for diabetes or metabolic syndrome have reduced breast can...

    Authors: Erin D. Giles, Sonali Jindal, Elizabeth A. Wellberg, Troy Schedin, Steven M. Anderson, Ann D. Thor, Dean P. Edwards, Paul S. MacLean and Pepper Schedin

    Citation: Breast Cancer Research 2018 20:50

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  49. Content type: Correction

    After the publication of this work [1] an error was noticed in Fig. 3a and Fig. 5a.

    Authors: Joan S. Lewis-Wambi, Helen R. Kim, Chris Wambi, Roshani Patel, Jennifer R. Pyle, Andres J. Klein-Szanto and V. Craig Jordan

    Citation: Breast Cancer Research 2018 20:57

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    The original article was published in Breast Cancer Research 2008 10:R104

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