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  1. Snail plays an important role in the epithelial-to-mesenchymal transition during development and in tumor progression. Induction of Snail expression coincides with drastic morphological changes in cultured epi...

    Authors: Bram De Craene and Geert Berx
    Citation: Breast Cancer Research 2006 8:105
  2. The mammary epithelium contains multipotent stem cells that give rise to all differentiated cell types present within the tissue. Mammary epithelial stem cells have been prospectively purified from dissociated...

    Authors: Magnus D Lynch, Massimiliano Cariati and Anand D Purushotham
    Citation: Breast Cancer Research 2006 8:211
  3. The introduction of comparative genomic hybridization (CGH) in 1992 opened new avenues in genomic investigation; in particular, it advanced analysis of solid tumours, including breast cancer, because it obviat...

    Authors: Erik H van Beers and Petra M Nederlof
    Citation: Breast Cancer Research 2006 8:210
  4. Candidate polymorphism-based genetic epidemiological studies have yielded little success in the search for low-penetrance breast cancer susceptibility genes. The lack of progress is partially due to insufficie...

    Authors: Yen-Ling Low, Sara Wedrén and Jianjun Liu
    Citation: Breast Cancer Research 2006 8:209
  5. Oestrogens can mediate some of their cell survival properties through a nongenomic mechanism that involves the mitogen-activated protein kinase (MAPK) pathway. The mechanism of this rapid signalling and its de...

    Authors: Kheng Tian Lim, Niamh Cosgrave, Arnold David Hill and Leonie S Young
    Citation: Breast Cancer Research 2006 8:R33

    The Correction to this article has been published in Breast Cancer Research 2018 20:61

  6. It is well established that women with high mammographic density are at greater risk for breast cancer than are women with low breast density. However, little research has been done on mammographic density and...

    Authors: Jasmeet K Gill, Gertraud Maskarinec, Ian Pagano and Laurence N Kolonel
    Citation: Breast Cancer Research 2006 8:R30
  7. The aim of this study was to examine the effect of the cellular composition of biopsies on the error rates of multigene predictors of response of breast tumours to neoadjuvant adriamycin and cyclophosphamide (...

    Authors: Susan J Cleator, Trevor J Powles, Tim Dexter, Laura Fulford, Alan Mackay, Ian E Smith, Haukur Valgeirsson, Alan Ashworth and Mitch Dowsett
    Citation: Breast Cancer Research 2006 8:R32
  8. Biological markers that reliably predict clinical or pathological response to primary systemic therapy early during a course of chemotherapy may have considerable clinical potential. This study evaluated chang...

    Authors: Russell Burcombe, George D Wilson, Mitch Dowsett, Ifty Khan, Paul I Richman, Frances Daley, Simone Detre and Andreas Makris
    Citation: Breast Cancer Research 2006 8:R31
  9. Keratin 6 (K6) has previously been identified as a marker of early mammary gland development and has also been proposed to be a marker of mammary gland progenitor cells. However, the function of K6 in the mamm...

    Authors: Sandra L Grimm, Wen Bu, Mary Ann Longley, Dennis R Roop, Yi Li and Jeffrey M Rosen
    Citation: Breast Cancer Research 2006 8:R29
  10. Matrix metalloproteinase (MMP)-2 is very active at degrading extracellular matrix. It is under the influence of an activator, membrane type 1 MMP (MMP-14), and the tissue inhibitor of metalloproteases (TIMP)-2...

    Authors: Bernard Têtu, Jacques Brisson, Chang Shu Wang, Hélène Lapointe, Geneviève Beaudry, Caty Blanchette and Dominique Trudel
    Citation: Breast Cancer Research 2006 8:R28
  11. Mucin 1 (MUC1) is a high molecular weight glycoprotein overexpressed on adenocarcinoma cells and is a target for immunotherapy protocols. To date, clinical trials against MUC1 have included advanced cancer pat...

    Authors: Vasso Apostolopoulos, Geoffrey A Pietersz, Anastasios Tsibanis, Annivas Tsikkinis, Heleni Drakaki, Bruce E Loveland, Sara J Piddlesden, Magdalena Plebanski, Dodie S Pouniotis, Michael N Alexis, Ian F McKenzie and Stamatis Vassilaros
    Citation: Breast Cancer Research 2006 8:R27
  12. Human RAD51 is a homologue of the Escherichia coli RecA protein and is known to function in recombinational repair of double-stranded DNA breaks. Mutations in the lower eukaryotic homologues of RAD51 result in a ...

    Authors: Felicity Lose, Paul Lovelock, Georgia Chenevix-Trench, Graham J Mann, Gulietta M Pupo and Amanda B Spurdle
    Citation: Breast Cancer Research 2006 8:R26
  13. Models of breast cancer incidence have evolved from the observation by Armitage and Doll in the 1950s that the pattern of incidence by age differs for reproductive cancers from those of other major malignancie...

    Authors: Graham A Colditz and Bernard A Rosner
    Citation: Breast Cancer Research 2006 8:208
  14. The Oncotype DX assay was recently reported to predict risk for distant recurrence among a clinical trial population of tamoxifen-treated patients with lymph node-negative, estrogen receptor (ER)-positive brea...

    Authors: Laurel A Habel, Steven Shak, Marlena K Jacobs, Angela Capra, Claire Alexander, Mylan Pho, Joffre Baker, Michael Walker, Drew Watson, James Hackett, Noelle T Blick, Deborah Greenberg, Louis Fehrenbacher, Bryan Langholz and Charles P Quesenberry
    Citation: Breast Cancer Research 2006 8:R25

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