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HER2 therapy: Molecular mechanisms of trastuzumab resistance

Trastuzumab is a monoclonal antibody targeted against the HER2 tyrosine kinase receptor. The majority of patients with metastatic breast cancer who initially respond to trastuzumab develop resistance within on...

Authors: Rita Nahta and Francisco J Esteva

Citation: Breast Cancer Research 2006 8:215

Content type: Review Published on: 6 November 2006
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Is transforming growth factor beta signalling required for breast cancer metastatic cell motility?

Authors: S Giampieri and E Sahai

Citation: Breast Cancer Research 2006 8(Suppl 2):P44

Content type: Poster Presentation Published on: 1 November 2006

This article is part of a Supplement: Volume 8 Supplement 2
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Role of macrophages in breast cancer angiogenesis in vivo

Authors: NJ Brown, L Bingle, MWR Reed and CE Lewis

Citation: Breast Cancer Research 2006 8(Suppl 2):P43

Content type: Poster Presentation Published on: 1 November 2006

This article is part of a Supplement: Volume 8 Supplement 2
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Setting a lower risk threshold for surveillance within breast cancer family services

Authors: R Black, A Fordyce, M Reis, D Goudie, L McLeish, H Carnaghan, E Anderson, J Campbell, H Gregor, E Smyth, R Davidson and M Steel

Citation: Breast Cancer Research 2006 8(Suppl 2):P42

Content type: Poster Presentation Published on: 1 November 2006

This article is part of a Supplement: Volume 8 Supplement 2
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'I haven't had breast cancer but I've had a mastectomy anyway': do women with ductal carcinoma in situhave appearance concerns?

Authors: F Kennedy, D Harcourt and N Rumsey

Citation: Breast Cancer Research 2006 8(Suppl 2):P41

Content type: Poster Presentation Published on: 1 November 2006

This article is part of a Supplement: Volume 8 Supplement 2
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Breast cancer follow-up: a focus group and interview study

Authors: CA Hughes and J Connolley

Citation: Breast Cancer Research 2006 8(Suppl 2):P40

Content type: Poster Presentation Published on: 1 November 2006

This article is part of a Supplement: Volume 8 Supplement 2
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Effects of combined treatment with Zometa and Taxol on endothelial cells in vitro

Authors: M Michailidou, N Brown, RE Coleman and I Holen

Citation: Breast Cancer Research 2006 8(Suppl 2):P39

Content type: Poster Presentation Published on: 1 November 2006

This article is part of a Supplement: Volume 8 Supplement 2
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Development of breast cancer immunotherapy using MUC1 retargeted T lymphocytes

Authors: S Wilkie, MK Brenner, J Taylor-Papadimitriou, J Burchell and J Maher

Citation: Breast Cancer Research 2006 8(Suppl 2):P38

Content type: Poster Presentation Published on: 1 November 2006

This article is part of a Supplement: Volume 8 Supplement 2
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Development of small-molecule transforming growth factor beta antagonists

Authors: DJ Warner, RB Sessions, D Dawbarn, SS Prime, SJ Allen and IC Paterson

Citation: Breast Cancer Research 2006 8(Suppl 2):P37

Content type: Poster Presentation Published on: 1 November 2006

This article is part of a Supplement: Volume 8 Supplement 2
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Synergistic effects of cytotoxic drugs and antiresorptive agents in vitro and in vivo

Authors: PD Ottewell, M Jones, RE Coleman and I Holen

Citation: Breast Cancer Research 2006 8(Suppl 2):P36

Content type: Poster Presentation Published on: 1 November 2006

This article is part of a Supplement: Volume 8 Supplement 2
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Why do most c-erbB-2/HER-2-positive breast cancer patients fail to respond to Herceptin?

Authors: ML Murphy, SKW Chan, L Bazley, NVL Hayes and WJ Gullick

Citation: Breast Cancer Research 2006 8(Suppl 2):P35

Content type: Poster Presentation Published on: 1 November 2006

This article is part of a Supplement: Volume 8 Supplement 2
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The Cambridge breast intensity modulated radiotherapy trial

Authors: CE Coles, JS Wilkinson, AM Moody, ACF Hoole, N Twyman and NG Burnet

Citation: Breast Cancer Research 2006 8(Suppl 2):P34

Content type: Poster Presentation Published on: 1 November 2006

This article is part of a Supplement: Volume 8 Supplement 2
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Global histone modifications in breast cancer and their prognostic significance

Authors: AR Green, S El-Shiekh, EA Rakha, EC Paish, DM Heery and IO Ellis

Citation: Breast Cancer Research 2006 8(Suppl 2):P33

Content type: Poster Presentation Published on: 1 November 2006

This article is part of a Supplement: Volume 8 Supplement 2
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Development of anti-MUC1 DNA aptamers for the imaging and radiotherapy of breast cancer

Authors: C Da Pieve, JN Iley, A Perkins and S Missailidis

Citation: Breast Cancer Research 2006 8(Suppl 2):P32

Content type: Poster Presentation Published on: 1 November 2006

This article is part of a Supplement: Volume 8 Supplement 2
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Increased regulatory T-cell numbers distinguish high-risk breast cancer patients and those at risk of late relapse

Authors: GJ Bates, SB Fox, C Han, RD Leek, JF Garcia, AL Harris and AH Banham

Citation: Breast Cancer Research 2006 8(Suppl 2):P31

Content type: Poster Presentation Published on: 1 November 2006

This article is part of a Supplement: Volume 8 Supplement 2
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Breast cancer in relation to childhood parental divorce and early adult psychiatric disorder in a British birth cohort

Authors: AU Lokugamage, M Hotopf, R Hardy, G Mishra, S Butterworth, MEJ Wadsworth and D Kuh

Citation: Breast Cancer Research 2006 8(Suppl 2):P30

Content type: Poster Presentation Published on: 1 November 2006

This article is part of a Supplement: Volume 8 Supplement 2
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Effect of intermittent versus chronic energy restriction on breast cancer risk biomarkers in premenopausal women: a randomised pilot trial

Authors: M Harvie, M Chapman, J Cuzick, A Flyvbjerg, P Hopwood, S Jebb, G Parfitt and A Howell

Citation: Breast Cancer Research 2006 8(Suppl 2):P29

Content type: Poster Presentation Published on: 1 November 2006

This article is part of a Supplement: Volume 8 Supplement 2
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Association of gene variants in the transforming growth factor beta signalling pathways with invasive breast cancer risk

Authors: S Scollen, AM Dunning, R Hesketh and JC Metcalfe

Citation: Breast Cancer Research 2006 8(Suppl 2):P28

Content type: Poster Presentation Published on: 1 November 2006

This article is part of a Supplement: Volume 8 Supplement 2
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High-grade ER-negative tumour breast cancers are characteristic of both very young onset cases and patients with hereditary breast cancer

Authors: D Eccles, S Gerty and P Simmonds

Citation: Breast Cancer Research 2006 8(Suppl 2):P27

Content type: Poster Presentation Published on: 1 November 2006

This article is part of a Supplement: Volume 8 Supplement 2
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New molecular tools and optical technologies to dissect CXCR4 function in breast cancer

Authors: PW Thavasu, F Festy, R Springall, K Ryder, R Waters, M Kelleher, S Pinder, C Gillett and T Ng

Citation: Breast Cancer Research 2006 8(Suppl 2):P25

Content type: Poster Presentation Published on: 1 November 2006

This article is part of a Supplement: Volume 8 Supplement 2
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Progress towards unlocking the secrets of oestrogen receptor beta in breast cancer

Authors: V Speirs, MD Parker, AR Green, IO Ellis, AM Hanby, PTK Saunders and AM Shaaban

Citation: Breast Cancer Research 2006 8(Suppl 2):P24

Content type: Poster Presentation Published on: 1 November 2006

This article is part of a Supplement: Volume 8 Supplement 2
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Role of protein kinase B in breast cancer

Authors: EM Sale, CP Hodgkinson, NP Jones and GJ Sale

Citation: Breast Cancer Research 2006 8(Suppl 2):P23

Content type: Poster Presentation Published on: 1 November 2006

This article is part of a Supplement: Volume 8 Supplement 2
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Role of the metastasis suppressor tetraspanin CD82/KAI 1 in regulation of signalling in breast cancer cells

Authors: E Odintsova and F Berditchevski

Citation: Breast Cancer Research 2006 8(Suppl 2):P21

Content type: Poster Presentation Published on: 1 November 2006

This article is part of a Supplement: Volume 8 Supplement 2
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Evaluation of migration-stimulating factor expression for breast cancer diagnosis and prognosis

Authors: SJ Jones, IR Ellis, K Kankova, AM Thompson, P Preece, S Kazmi, SL Schor and AM Schor

Citation: Breast Cancer Research 2006 8(Suppl 2):P19

Content type: Poster Presentation Published on: 1 November 2006

This article is part of a Supplement: Volume 8 Supplement 2
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Role of the Brk tyrosine kinase in breast cancer progression

Authors: AJ Harvey, W Court, G Box, SA Eccles and MR Crompton

Citation: Breast Cancer Research 2006 8(Suppl 2):P17

Content type: Poster Presentation Published on: 1 November 2006

This article is part of a Supplement: Volume 8 Supplement 2
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AGR2, a novel metastasis inducing protein with an effect on breast cancer patient survival

Authors: DL Barraclough, H Innes, S Taylor, MPA Davies, A Platt-Higgins, DR Sibson, PS Rudland and R Barraclough

Citation: Breast Cancer Research 2006 8(Suppl 2):P15

Content type: Poster Presentation Published on: 1 November 2006

This article is part of a Supplement: Volume 8 Supplement 2
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Potential role of cyclin D₁in DNA damage response

Authors: N Suwaki and DJ Mann

Citation: Breast Cancer Research 2006 8(Suppl 2):P13

Content type: Poster Presentation Published on: 1 November 2006

This article is part of a Supplement: Volume 8 Supplement 2
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Benefits of combined treatments using antiresorptive agents and cytotoxic drugs

Authors: I Holen, H Neville-Webbe and RE Coleman

Citation: Breast Cancer Research 2006 8(Suppl 2):S12

Content type: Oral Presentation Published on: 1 November 2006

This article is part of a Supplement: Volume 8 Supplement 2
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Role of CASP8 D302H and other apoptosis gene variants in breast cancer

Authors: SH Mistry, S Rafii, AL Shippen, G MacPherson, S Balasubramanian, MW Reed and A Cox

Citation: Breast Cancer Research 2006 8(Suppl 2):P11

Content type: Poster Presentation Published on: 1 November 2006

This article is part of a Supplement: Volume 8 Supplement 2
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Microarray studies reveal novel genes associated with endocrine resistance in breast cancer

Authors: RS Burmi, RA McClelland, D Barrow, IO Ellis, JFR Robertson, RI Nicholson and JMW Gee

Citation: Breast Cancer Research 2006 8(Suppl 2):S11

Content type: Oral Presentation Published on: 1 November 2006

This article is part of a Supplement: Volume 8 Supplement 2
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Characterization of peptide aptamers to the Anterior Gradient 2: a novel inhibitor of the tumour suppressor protein p53

Authors: A Fourtouna, E Murray, L Hayward, L Pohler and T Hupp

Citation: Breast Cancer Research 2006 8(Suppl 2):P10

Content type: Poster Presentation Published on: 1 November 2006

This article is part of a Supplement: Volume 8 Supplement 2
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Genome-wide RNAi to identify genes that confer synthetic lethality with BRCA1

Authors: MIR Petalcorin, JS Martin and SJ Boulton

Citation: Breast Cancer Research 2006 8(Suppl 2):S10

Content type: Oral Presentation Published on: 1 November 2006

This article is part of a Supplement: Volume 8 Supplement 2
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Inhibitor of apoptosis proteins in breast cancer

Authors: FM Foster and CH Streuli

Citation: Breast Cancer Research 2006 8(Suppl 2):P9

Content type: Poster Presentation Published on: 1 November 2006

This article is part of a Supplement: Volume 8 Supplement 2
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Novel roles for integrins in tumour angiogenesis

Authors: M Germain, R Silva, L Reynolds, S Robinson, M DiPersio, J Kreidberg, E Georges-Labouesse and K Hodivala-Dilke

Citation: Breast Cancer Research 2006 8(Suppl 2):S9

Content type: Oral Presentation Published on: 1 November 2006

This article is part of a Supplement: Volume 8 Supplement 2
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Investigating the role of Wnt signalling in lobuloalveolar development of the mammary gland

Authors: RJ Evans and C Dale

Citation: Breast Cancer Research 2006 8(Suppl 2):P8

Content type: Poster Presentation Published on: 1 November 2006

This article is part of a Supplement: Volume 8 Supplement 2
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Aberrant activation of Notch signalling in human breast cancer

Authors: S Stylianou, GM Collu, RB Clarke and K Brennan

Citation: Breast Cancer Research 2006 8(Suppl 2):S8

Content type: Oral Presentation Published on: 1 November 2006

This article is part of a Supplement: Volume 8 Supplement 2
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Poly(ADPribosyl)ation of CTCF: role in breast tumourigenesis

Authors: F Docquier, D Farrar, I Chernukhin and E Klenova

Citation: Breast Cancer Research 2006 8(Suppl 2):P7

Content type: Poster Presentation Published on: 1 November 2006

This article is part of a Supplement: Volume 8 Supplement 2
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Regulation of human breast stem cells

Authors: RB Clarke

Citation: Breast Cancer Research 2006 8(Suppl 2):S7

Content type: Oral Presentation Published on: 1 November 2006

This article is part of a Supplement: Volume 8 Supplement 2
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hCLK2 couples FANCD2 to stalled replication forks and functions in the mammalian S-phase checkpoint

Authors: SJ Collis, LJ Barber, JS Martin, JD Ward and SJ Boulton

Citation: Breast Cancer Research 2006 8(Suppl 2):P6

Content type: Poster Presentation Published on: 1 November 2006

This article is part of a Supplement: Volume 8 Supplement 2
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Chromosome translocations may play a significant role in breast cancer

Authors: KL Howarth, KA Blood, JC Pole, SL Cooke, Y-L Chua, JC Beavis, B-L Ng and PAW Edwards

Citation: Breast Cancer Research 2006 8(Suppl 2):S6

Content type: Oral Presentation Published on: 1 November 2006

This article is part of a Supplement: Volume 8 Supplement 2
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The NEUREGULIN1gene and breast cancer

Authors: YL Chua and PAW Edwards

Citation: Breast Cancer Research 2006 8(Suppl 2):P5

Content type: Poster Presentation Published on: 1 November 2006

This article is part of a Supplement: Volume 8 Supplement 2
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Regulation of recombinational repair by the familial breast cancer susceptibility protein BRCA2

Authors: SC West and F Esashi

Citation: Breast Cancer Research 2006 8(Suppl 2):S5

Content type: Oral Presentation Published on: 1 November 2006

This article is part of a Supplement: Volume 8 Supplement 2
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Role of BRCT motif containing proteins in Chk1 activation

Authors: RG Beniston and CGW Smythe

Citation: Breast Cancer Research 2006 8(Suppl 2):P4

Content type: Poster Presentation Published on: 1 November 2006

This article is part of a Supplement: Volume 8 Supplement 2
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BRCA1 transcriptionally regulates genes associated with the basal breast cancer phenotype

Authors: JE Quinn, CR James, JJ Gorskii, PB Mullan and DP Harkin

Citation: Breast Cancer Research 2006 8(Suppl 2):S4

Content type: Oral Presentation Published on: 1 November 2006

This article is part of a Supplement: Volume 8 Supplement 2
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Characterisation of the tumour suppressor gene ZACin breast tissue

Authors: EM Valleley, SF Cordery, M Shires, V Speirs and DT Bonthron

Citation: Breast Cancer Research 2006 8(Suppl 2):P3

Content type: Poster Presentation Published on: 1 November 2006

This article is part of a Supplement: Volume 8 Supplement 2
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Evolution of aromatase inhibitors as an endocrine treatment for breast cancer

Authors: WR Miller

Citation: Breast Cancer Research 2006 8(Suppl 2):S3

Content type: Oral Presentation Published on: 1 November 2006

This article is part of a Supplement: Volume 8 Supplement 2
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Phenotypic characterization of mouse mammary epithelial stem and progenitor cells

Authors: J Stingl, CJ Eaves and CJ Watson

Citation: Breast Cancer Research 2006 8(Suppl 2):P2

Content type: Poster Presentation Published on: 1 November 2006

This article is part of a Supplement: Volume 8 Supplement 2
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Translating breast cancer research into clinical practice — new approaches and better outcomes

Authors: SRD Johnston

Citation: Breast Cancer Research 2006 8(Suppl 2):2

Content type: Oral Presentation Published on: 1 November 2006

This article is part of a Supplement: Volume 8 Supplement 2
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Loss of C-terminal binding protein transcriptional corepressor leads to aberrant mitosis and cell death in breast cancer cells

Authors: L Bergman and J Blaydes

Citation: Breast Cancer Research 2006 8(Suppl 2):P1

Content type: Poster Presentation Published on: 1 November 2006

This article is part of a Supplement: Volume 8 Supplement 2
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Breast cancer susceptibility after BRCA1/2: finding the genes and potential practical applications

Authors: BAJ Ponder, AM Dunning, DF Easton and PDP Pharoah

Citation: Breast Cancer Research 2006 8(Suppl 2):S1

Content type: Oral Presentation Published on: 1 November 2006

This article is part of a Supplement: Volume 8 Supplement 2
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