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  1. Endocrine therapies target oestrogenic stimulation of breast cancer (BC) growth, but resistance remains problematic. Our aims in this study were (1) to identify genes most strongly associated with resistance t...

    Authors: Ricardo Ribas, Zara Ghazoui, Qiong Gao, Sunil Pancholi, Aradhana Rani, Anita Dunbier, Mitch Dowsett and Lesley-Ann Martin
    Citation: Breast Cancer Research 2014 16:447
  2. Triple-negative breast cancers, particularly the claudin-low subtype, are highly aggressive and exhibit increased tumor-initiating cell (TIC) characteristics. In this study, we demonstrate that vascular endoth...

    Authors: Chu-An Wang, J Chuck Harrell, Ritsuko Iwanaga, Paul Jedlicka and Heide L Ford
    Citation: Breast Cancer Research 2014 16:462
  3. Following a highly dynamic and complex dialogue between the epithelium and the surrounding microenvironment, the mammary gland develops into a branching structure during puberty, buds during pregnancy, forms i...

    Authors: Paola Nisticò, Francesca Di Modugno, Sheila Spada and Mina J Bissell
    Citation: Breast Cancer Research 2014 16:459
  4. The purpose of this study is to develop a prediction model utilizing tumor hemoglobin parameters measured by ultrasound-guided near-infrared optical tomography (US-NIR) in conjunction with standard pathologic ...

    Authors: Quing Zhu, Liqun Wang, Susan Tannenbaum, Andrew Ricci, Patricia DeFusco and Poornima Hegde
    Citation: Breast Cancer Research 2014 16:456
  5. Obesity is a known risk factor for breast cancer. Sphingosine kinase 1 (SK1) is an oncogenic lipid kinase that is overexpressed in breast tumours and linked with poor prognosis, however, its role in obesity-dr...

    Authors: Heba Alshaker, Jonathan Krell, Adam E Frampton, Jonathan Waxman, Oleg Blyuss, Alexey Zaikin, Mathias Winkler, Justin Stebbing, Ernesto Yagüe and Dmitri Pchejetski
    Citation: Breast Cancer Research 2014 16:426
  6. Transducin (β)-like 1 X-linked receptor 1(TBLR1) is an F-box-like and WD repeat-containing protein which functions as a switch in transcriptional activation, However, the clinical significance and biological r...

    Authors: Xinghua Li, Weijiang Liang, Junling Liu, Chuyong Lin, Shu Wu, Libing Song and Zhongyu Yuan
    Citation: Breast Cancer Research 2014 16:465
  7. Massively parallel DNA and RNA sequencing approaches have generated data on thousands of breast cancer genomes. In this review, we consider progress largely from the perspective of new concepts and hypotheses ...

    Authors: Rodrigo Goncalves, Wayne A Warner, Jingqin Luo and Matthew J Ellis
    Citation: Breast Cancer Research 2014 16:460
  8. DNA methylation is a well-studied biomarker in invasive breast cancer, but its role in ductal carcinoma in situ (DCIS) is less well characterized. The aims of this study are to assess the methylation profile in D...

    Authors: Jia-Min B Pang, Siddhartha Deb, Elena A Takano, David J Byrne, Nicholas Jene, Alice Boulghourjian, Anne Holliday, Ewan Millar, C Soon Lee, Sandra A O’Toole, Alexander Dobrovic and Stephen B Fox
    Citation: Breast Cancer Research 2014 16:423
  9. Lineage tracing studies in mice have revealed the localization and existence of lineage-restricted mammary epithelial progenitor cells that functionally contribute to expansive growth during puberty and differ...

    Authors: Lisa M Arendt, Patricia J Keller, Adam Skibinski, Kevin Goncalves, Stephen P Naber, Rachel J Buchsbaum, Hannah Gilmore, Steven E Come and Charlotte Kuperwasser
    Citation: Breast Cancer Research 2014 16:453
  10. The onset of distal metastasis, which underlies the high mortality of breast cancers, warrants substantial studies to depict its molecular basis. Nuclear factor of activated T cells 5 (NFAT5) is upregulated in...

    Authors: Jun-Tang Li, Li-Feng Wang, Ya-Li Zhao, Tao Yang, Wei Li, Jing Zhao, Feng Yu, Lei Wang, Yan-Ling Meng, Ning-Ning Liu, Xiao-Shan Zhu, Chun-Fang Gao, Lin-Tao Jia and An-Gang Yang
    Citation: Breast Cancer Research 2014 16:454

    The Retraction Note to this article has been published in Breast Cancer Research 2018 20:77

  11. Estrogen forms a complex with the estrogen receptor (ER) that binds to estrogen response elements (EREs) in the regulatory region of estrogen-responsive genes and regulates their transcription. Sequence varian...

    Authors: Chia-Ni Hsiung, Hou-Wei Chu, Yuan-Ling Huang, Wen-Cheng Chou, Ling-Yueh Hu, Huan-Ming Hsu, Pei-Ei Wu, Ming-Feng Hou, Jyh-Cherng Yu and Chen-Yang Shen
    Citation: Breast Cancer Research 2014 16:455
  12. Circulating tumor cells (CTCs) are tumor cells shed from either primary tumors or its metastases that circulate in the peripheral blood of patients with metastatic cancers. The molecular characterization of th...

    Authors: Sandra V Fernandez, Catherine Bingham, Patricia Fittipaldi, Laura Austin, Juan Palazzo, Gary Palmer, Katherine Alpaugh and Massimo Cristofanilli
    Citation: Breast Cancer Research 2014 16:445
  13. Mammographic density is well-established as a risk factor for breast cancer, however, adjustment for age and body mass index (BMI) is vital to its clinical interpretation when assessing individual risk. In thi...

    Authors: Jane Warwick, Hanna Birke, Jennifer Stone, Ruth ML Warren, Elizabeth Pinney, Adam R Brentnall, Stephen W Duffy, Anthony Howell and Jack Cuzick
    Citation: Breast Cancer Research 2014 16:451

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