Cadigan KM, Nusse R: Wnt signaling: a common theme in animal development. Genes Dev. 1997, 11: 3286-3305.
Article
CAS
PubMed
Google Scholar
Heasman J, Crawford A, Goldstone K, Garner-Hamrick P, Gumbiner B, McCrea P, Kintner C, Noro CY, Wylie C: Overexpression of cadherins and underexpression of beta-catenin inhibit dorsal mesoderm induction in early Xenopus embryos. Cell. 1994, 79: 791-803.
Article
CAS
PubMed
Google Scholar
Haegel H, Larue L, Ohsugi M, Fedorov L, Herrenknecht K, Kemler R: Lack of beta-catenin affects mouse development at gastrulation. Development. 1995, 121: 3529-3537.
CAS
PubMed
Google Scholar
Huelsken J, Vogel R, Brinkmann V, Erdmann B, Birchmeier C, Birchmeier W: Requirement for beta-catenin in anterior–posterior axis formation in mice. J Cell Biol. 2000, 148: 567-578. 10.1083/jcb.148.3.567.
Article
PubMed Central
CAS
PubMed
Google Scholar
Brault V, Moore R, Kutsch S, Ishibashi M, Rowitch DH, McMahon AP, Sommer L, Boussadia O, Kemler R: Inactivation of the beta-catenin gene by Wnt1-Cre-mediated deletion results in dramatic brain malformation and failure of craniofacial development. Development. 2001, 128: 1253-1264.
CAS
PubMed
Google Scholar
Polakis P: Wnt signaling and cancer. Genes Dev. 2000, 14: 1837-1851.
CAS
PubMed
Google Scholar
Candidus S, Bischoff P, Becker KF, Hofler H: No evidence for mutations in the alpha- and beta-catenin genes in human gastric and breast carcinomas. Cancer Res. 1996, 56: 49-52.
CAS
PubMed
Google Scholar
Lin SY, Xia W, Wang JC, Kwong KY, Spohn B, Wen Y, Pestell RG, Hung MC: Beta-catenin, a novel prognostic marker for breast cancer: its roles in cyclin D1 expression and cancer progression. Proc Natl Acad Sci USA. 2000, 97: 4262-4266. 10.1073/pnas.060025397.
Article
PubMed Central
CAS
PubMed
Google Scholar
Michaelson JS, Leder P: Beta-catenin is a downstream effector of Wnt-mediated tumorigenesis in the mammary gland. Oncogene. 2001, 20: 5093-5099. 10.1038/sj.onc.1204586.
Article
CAS
PubMed
Google Scholar
Imbert A, Eelkema R, Jordan S, Feiner H, Cowin P: Delta N89 beta-catenin induces precocious development, differentiation, and neoplasia in mammary gland. J Cell Biol. 2001, 153: 555-568. 10.1083/jcb.153.3.555.
Article
PubMed Central
CAS
PubMed
Google Scholar
Lane TF, Leder P: Wnt-10b directs hypermorphic development and transformation in mammary glands of male and female mice. Oncogene. 1997, 15: 2133-2144. 10.1038/sj.onc.1201593.
Article
CAS
PubMed
Google Scholar
Tsukamoto AS, Grosschedl R, Guzman RC, Parslow T, Varmus HE: Expression of the int-1 gene in transgenic mice is associated with mammary gland hyperplasia and adenocarcinomas in male and female mice. Cell. 1988, 55: 619-625.
Article
CAS
PubMed
Google Scholar
He TC, Sparks AB, Rago C, Hermeking H, Zawel L, da Costa LT, Morin PJ, Vogelstein B, Kinzler KW: Identification of c-MYC as a target of the APC pathway. Science. 1998, 281: 1509-1512. 10.1126/science.281.5382.1509.
Article
CAS
PubMed
Google Scholar
Shtutman M, Zhurinsky J, Simcha I, Albanese C, D'Amico M, Pestell R, Ben-Ze'ev A: The cyclin D1 gene is a target of the beta-catenin/LEF-1 pathway. Proc Natl Acad Sci USA. 1999, 96: 5522-5527. 10.1073/pnas.96.10.5522.
Article
PubMed Central
CAS
PubMed
Google Scholar
Tetsu O, McCormick F: Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells. Nature. 1999, 398: 422-426. 10.1038/18884.
Article
CAS
PubMed
Google Scholar
Miyoshi K, Shillingford JM, Le Provost F, Gounari F, Bronson R, von Boehmer H, Taketo MM, Cardiff RD, Hennighausen L, Khazaie K: Activation of beta-catenin signaling in differentiated mammary secretory cells induces transdifferentiation into epidermis and squamous metaplasias. Proc Natl Acad Sci USA. 2002, 99: 219-224. 10.1073/pnas.012414099.
Article
PubMed Central
CAS
PubMed
Google Scholar
Harada N, Tamai Y, Ishikawa T, Sauer B, Takaku K, Oshima M, Taketo MM: Intestinal polyposis in mice with a dominant stable mutation of the beta-catenin gene. EMBO J. 1999, 18: 5931-5942. 10.1093/emboj/18.21.5931.
Article
PubMed Central
CAS
PubMed
Google Scholar
Miyoshi K, Rosner A, Nozawa M, Byrd C, Morgan F, Landesman-Bollag E, Xu X, Seldin DC, Schmidt EV, Taketo MM, Robinson GW, Cardiff RD, Hennighausen L: Activation of different Wnt/beta-catenin signaling components in mammary epithelium induces transdifferentiation and the formation of pilar tumors. Oncogene. 2002, 21: 5548-5556. 10.1038/sj.onc.1205686.
Article
CAS
PubMed
Google Scholar
Rosner A, Miyoshi K, Landesman-Bollag E, Xu X, Seldin DC, Moser AR, MacLeod CL, Shyamala G, Gillgrass AE, Cardiff RD: Pathway pathology: histological differences between ErbB/Ras and Wnt pathway transgenic mammary tumors. Am J Pathol. 2002, 161: 1087-1097.
Article
PubMed Central
CAS
PubMed
Google Scholar
Korinek V, Barker N, Morin PJ, van Wichen D, de Weger R, Kinzler KW, Vogelstein B, Clevers H: Constitutive transcriptional activation by a beta-catenin–Tcf complex in APC-/- colon carcinoma. Science. 1997, 275: 1784-1787. 10.1126/science.275.5307.1784.
Article
CAS
PubMed
Google Scholar
Rubinfeld B, Robbins P, El-Gamil M, Albert I, Porfiri E, Polakis P: Stabilization of beta-catenin by genetic defects in melanoma cell lines. Science. 1997, 275: 1790-1792. 10.1126/science.275.5307.1790.
Article
CAS
PubMed
Google Scholar
Gallagher RC, Hay T, Meniel V, Naughton C, Anderson TJ, Shibata H, Ito M, Clevers H, Noda T, Sansom OJ, Mason JO, Clarke AR: Inactivation of Apc perturbs mammary development, but only directly results in acanthoma in the context of Tcf-1 deficiency. Oncogene. 2002, 21: 6446-6457. 10.1038/sj.onc.1205892.
Article
CAS
PubMed
Google Scholar
Wong NA, Pignatelli M: Beta-catenin – a linchpin in colorectal carcinogenesis?. Am J Pathol. 2002, 160: 389-401.
Article
PubMed Central
CAS
PubMed
Google Scholar
Takahashi K, Suzuki K, Tsukatani Y: Induction of tyrosine phosphorylation and association of beta-catenin with EGF receptor upon tryptic digestion of quiescent cells at confluence. Oncogene. 1997, 15: 71-78. 10.1038/sj.onc.1201160.
Article
CAS
PubMed
Google Scholar
Shibata T, Ochiai A, Kanai Y, Akimoto S, Gotoh M, Yasui N, Machinami R, Hirohashi S: Dominant negative inhibition of the association between beta-catenin and c-erbB-2 by N-terminally deleted beta-catenin suppresses the invasion and metastasis of cancer cells. Oncogene. 1996, 13: 883-889.
CAS
PubMed
Google Scholar
Danilkovitch-Miagkova A, Miagkov A, Skeel A, Nakaigawa N, Zbar B, Leonard EJ: Oncogenic mutants of RON and MET receptor tyrosine kinases cause activation of the beta-catenin pathway. Mol Cell Biol. 2001, 21: 5857-5868. 10.1128/MCB.21.17.5857-5868.2001.
Article
PubMed Central
CAS
PubMed
Google Scholar
Kang D, Soriano S, Xia X, Eberhart C, De Strooper B, Zheng H, Koo E: Presenilin couples the paired phosphorylation of beta-catenin independent of axin. Implications for beta-catenin activation in tumorigenesis. Cell. 2002, 110: 751-762. 10.1016/S0092-8674(02)00970-4.
Article
CAS
PubMed
Google Scholar
Liu C, Li Y, Semenov M, Han C, Baeg GH, Tan Y, Zhang Z, Lin X, He X: Control of beta-catenin phosphorylation/degradation by a dual-kinase mechanism. Cell. 2002, 108: 837-847. 10.1016/S0092-8674(02)00685-2.
Article
CAS
PubMed
Google Scholar
Xia X, Qian S, Soriano S, Wu Y, Fletcher AM, Wang XJ, Koo EH, Wu X, Zheng H: Loss of presenilin 1 is associated with enhanced beta-catenin signaling and skin tumorigenesis. Proc Natl Acad Sci USA. 2001, 98: 10863-10868. 10.1073/pnas.191284198.
Article
PubMed Central
CAS
PubMed
Google Scholar
Lamberti C, Lin KM, Yamamoto Y, Verma U, Verma IM, Byers S, Gaynor RB: Regulation of beta-catenin function by the IkappaB kinases. J Biol Chem. 2001, 276: 42276-42286. 10.1074/jbc.M104227200.
Article
CAS
PubMed
Google Scholar
Landesman-Bollag E, Romieu-Mourez R, Song DH, Sonenshein GE, Cardiff RD, Seldin DC: Protein kinase CK2 in mammary gland tumorigenesis. Oncogene. 2001, 20: 3247-3257. 10.1038/sj.onc.1204411.
Article
CAS
PubMed
Google Scholar
Song DH, Sussman DJ, Seldin DC: Endogenous protein kinase CK2 participates in Wnt signaling in mammary epithelial cells. J Biol Chem. 2000, 275: 23790-23797. 10.1074/jbc.M909107199.
Article
CAS
PubMed
Google Scholar
Gat U, DasGupta R, Degenstein L, Fuchs E: De novo hair follicle morphogenesis and hair tumors in mice expressing a truncated beta-catenin in skin. Cell. 1998, 95: 605-614. 10.1016/S0092-8674(00)81631-1.
Article
CAS
PubMed
Google Scholar
Taylor G, Lehrer MS, Jensen PJ, Sun TT, Lavker RM: Involvement of follicular stem cells in forming not only the follicle but also the epidermis. Cell. 2000, 102: 451-461. 10.1016/S0092-8674(00)00050-7.
Article
CAS
PubMed
Google Scholar
Huelsken J, Vogel R, Erdmann B, Cotsarelis G, Birchmeier W: Beta-catenin controls hair follicle morphogenesis and stem cell differentiation in the skin. Cell. 2001, 105: 533-545. 10.1016/S0092-8674(01)00336-1.
Article
CAS
PubMed
Google Scholar
Merrill BJ, Gat U, DasGupta R, Fuchs E: Tcf3 and Lef1 regulate lineage differentiation of multipotent stem cells in skin. Genes Dev. 2001, 15: 1688-1705. 10.1101/gad.891401.
Article
PubMed Central
CAS
PubMed
Google Scholar
Niemann C, Owens DM, Hulsken J, Birchmeier W, Watt FM: Expression of DeltaNLef1 in mouse epidermis results in differentiation of hair follicles into squamous epidermal cysts and formation of skin tumours. Development. 2002, 129: 95-109.
CAS
PubMed
Google Scholar
DasGupta R, Rhee H, Fuchs E: A developmental conundrum: a stabilized form of beta-catenin lacking the transcriptional activation domain triggers features of hair cell fate in epidermal cells and epidermal cell fate in hair follicle cells. J Cell Biol. 2002, 158: 331-344. 10.1083/jcb.200204134.
Article
PubMed Central
CAS
PubMed
Google Scholar
Gounari F, Signoretti S, Bronson R, Klein L, Sellers WR, Kum J, Siermann A, Taketo MM, von Boehmer H, Khazaie K: Stabilization of beta-catenin induces lesions reminiscent of prostatic intraepithelial neoplasia, but terminal squamous transdifferentiation of other secretory epithelia. Oncogene. 2002, 21: 4099-4107. 10.1038/sj.onc.1205562.
Article
CAS
PubMed
Google Scholar
Harada N, Miyoshi H, Murai N, Oshima H, Tamai Y, Oshima M, Taketo MM: Lack of tumorigenesis in the mouse liver after adenovirus-mediated expression of a dominant stable mutant of beta-catenin. Cancer Res. 2002, 62: 1971-1977.
CAS
PubMed
Google Scholar
Willert J, Epping M, Pollack J, Brown P, Nusse R: A transcriptional response to Wnt protein in human embryonic carcinoma cells. BMC Dev Biol. 2002, 2: 8-10.1186/1471-213X-2-8.
Article
PubMed Central
PubMed
Google Scholar