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Table 1 Gain-of-function of β-catenin signaling

From: β-Catenin: a transforming actor on many stages

Organ

Phenotype

References

Intestine

Polyps

Harada et al. [17]

Skin

Development of extra hair follicles, hair tumor

Gat et al. [33]

Mammary gland

Adenocarcinomas

Imbert et al. [10]

  

Michaelson and Leder [9]

 

Transdifferentiation, squamous metaplasias

Miyoshi et al. [16, 18]

Liver

No neoplasias

Harada et al. [40]

Prostate

Epithelial neoplasias

Gounari et al. [39]

 

Squamous transdifferentiation

Unpublished data

Salivery gland

Squamous metaplasias

Gounari et al. [39]

Harderian gland

Squamous metaplasias

 

Tooth

Odontoma