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Iodinated oestradiol-labeled oestrogen receptor (ER) isoforms devoid of amino-terminal ABC domains represent about two-thirds of the whole receptor population detected in cytosol samples from human breast canc...
Serial plasma samples from 1006 patients with breast cancer revealed: (i) no correlation of p53 autoantibody status with disease status at the time of sample collection, or with menopausal status at time of pr...
Breast cancer mortality rates have shown only modest improvemen despite the advent of effective chemotherapeutic agents which have been administered to a large percentage of women with breast cancer. In an eff...
Inflammatory breast cancer (IBC) is an aggressive form of locally advanced breast cancer (LABC) that effects approximately 5% of women with breast cancer annually in the USA. It is a clinically and pathologica...
During embryogenesis, the formation of primary vascular networks occurs via the processes of vasculogenesis and angiogenesis. In uveal melanoma, vasculogenic mimicry describes the 'embryonic-like' ability of a...
The present is an overview of recent data that describes the genetic underpinnings of the suppression of cancer metastasis. Despite the explosion of new information about the genetics of cancer, only six human...
Recent technological advances have led to an increasing ability to detect isolated tumour cells and groups of tumour cells in patients' blood, lymph nodes or bone marrow. However, the clinical significance of ...
Women's perceptions of breast cancer risk are largely inaccurate and are often associated with high levels of anxiety about cancer. There are interesting cultural differences that are not well researched. Gene...
Using a carcinogen-initiated rat model of mammary tumorigenesis, we tested the hypothesis that transforming growth factor (TGF)-βs are useful biomarkers of chemopreventive efficacy in the breast. The chemoprev...
Patients with abnormal breast findings (n = 413) were examined by mammography, sonography and magnetic resonance (MR) mammography; 185 invasive cancers, 38 carcinoma in situ and 254 benign tumours were confirmed ...
The present review addresses the capacity of optical imaging to resolve functional and molecular characteristics of breast cancer. We focus on recent developments in optical imaging that allow three-dimensiona...
The use of magnetic resonance spectroscopy (MRS) to investigate breast tumour biochemistry in vivo is reviewed. To this end, results obtained both from patients in vivo and from tumour extracts and model systems ...
The dysregulation of apoptosis contributes in a variety of ways to the malignant phenotype. It is increasingly recognized that the alteration of pro-apoptotic and anti-apoptotic molecules determines not only e...
A variety of imaging technologies is being investigated as tools for studying gene expression in living subjects. Two technologies that use radiolabeled isotopes are single photon emission computed tomography ...
Magnetic resonance imaging (MRI) techniques enable vascular function to be mapped with high spatial resolution. Current methods for imaging in breast cancer are described, and a review of recent studies that c...
Since its first introduction approximately 10 years ago, there has been extensive progress in the application of magnetic resonance imaging (MRI) to the detection and diagnosis of breast cancer. Contrast-enhan...
The breast myoepithelial cell is the Cinderella of mammary biology. Although its contribution to benign and some malignant pathologies is recognised, it has been largely neglected in molecular and biological s...
This article is part of a Supplement: Volume 2 Supplement 2
This article is part of a Supplement: Volume 2 Supplement 2
This article is part of a Supplement: Volume 2 Supplement 2
This article is part of a Supplement: Volume 2 Supplement 2
This article is part of a Supplement: Volume 2 Supplement 2
This article is part of a Supplement: Volume 2 Supplement 2
This article is part of a Supplement: Volume 2 Supplement 2
This article is part of a Supplement: Volume 2 Supplement 2
This article is part of a Supplement: Volume 2 Supplement 2
This article is part of a Supplement: Volume 2 Supplement 2
This article is part of a Supplement: Volume 2 Supplement 2
This article is part of a Supplement: Volume 2 Supplement 2
This article is part of a Supplement: Volume 2 Supplement 2
This article is part of a Supplement: Volume 2 Supplement 2
This article is part of a Supplement: Volume 2 Supplement 2
This article is part of a Supplement: Volume 2 Supplement 2
This article is part of a Supplement: Volume 2 Supplement 2
This article is part of a Supplement: Volume 2 Supplement 2
This article is part of a Supplement: Volume 2 Supplement 2
This article is part of a Supplement: Volume 2 Supplement 2
This article is part of a Supplement: Volume 2 Supplement 2
This article is part of a Supplement: Volume 2 Supplement 2
This article is part of a Supplement: Volume 2 Supplement 2
This article is part of a Supplement: Volume 2 Supplement 2
This article is part of a Supplement: Volume 2 Supplement 2
This article is part of a Supplement: Volume 2 Supplement 2
This article is part of a Supplement: Volume 2 Supplement 2
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