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We assessed the association between a glutamine repeat polymorphism in AIB1 and breast cancer risk in a case-control study (464 cases, 624 controls) nested within the Nurses' Health Study cohort. We observed no a...
Estrogen signaling has turned out to be much more complex and exciting than previously thought; the paradigm shift in our understanding of estrogen action came in 1996, when the presence of a new estrogen rece...
Estrogen receptors are members of the nuclear receptor steroid family that exhibit specific structural features, ligand-binding domain sequence identity and dimeric interactions, that single them out. The crys...
Natural, synthetic and environmental estrogens have numerous effects on the development and physiology of mammals. Estrogen is primarily known for its role in the development and functioning of the female repr...
Estrogens display intriguing tissue-selective action that is of great biomedical importance in the development of optimal therapeutics for the prevention and treatment of breast cancer, for menopausal hormone ...
Numerous models have been developed to address key elements in the biology of breast cancer development and progression. No model is ideal, but the most useful are those that reflect the natural history and hi...
Tumor suppressor genes that perform apparently generic cellular functions nonetheless cause tissue-specific syndromes in the human population when they are mutated in the germline. The two major hereditary bre...
An association between protein glycosylation and tumorigenesis has been recognized for over 10 years. Associations linking the importance of glycosylation events to tumor biology, especially the progression to...
This article is part of a Supplement: Volume 2 Supplement 2
This article is part of a Supplement: Volume 2 Supplement 2
This article is part of a Supplement: Volume 2 Supplement 2
This article is part of a Supplement: Volume 2 Supplement 2
This article is part of a Supplement: Volume 2 Supplement 2
This article is part of a Supplement: Volume 2 Supplement 2
This article is part of a Supplement: Volume 2 Supplement 2
This article is part of a Supplement: Volume 2 Supplement 2
This article is part of a Supplement: Volume 2 Supplement 2
This article is part of a Supplement: Volume 2 Supplement 2
This article is part of a Supplement: Volume 2 Supplement 2
This article is part of a Supplement: Volume 2 Supplement 2
This article is part of a Supplement: Volume 2 Supplement 2
This article is part of a Supplement: Volume 2 Supplement 2
This article is part of a Supplement: Volume 2 Supplement 2
This article is part of a Supplement: Volume 2 Supplement 2
This article is part of a Supplement: Volume 2 Supplement 2
This article is part of a Supplement: Volume 2 Supplement 2
This article is part of a Supplement: Volume 2 Supplement 2
This article is part of a Supplement: Volume 2 Supplement 2
This article is part of a Supplement: Volume 2 Supplement 2
This article is part of a Supplement: Volume 2 Supplement 2
This article is part of a Supplement: Volume 2 Supplement 2
This article is part of a Supplement: Volume 2 Supplement 2
This article is part of a Supplement: Volume 2 Supplement 2
This article is part of a Supplement: Volume 2 Supplement 2
This article is part of a Supplement: Volume 2 Supplement 2
This article is part of a Supplement: Volume 2 Supplement 2
This article is part of a Supplement: Volume 2 Supplement 2
This article is part of a Supplement: Volume 2 Supplement 2
This article is part of a Supplement: Volume 2 Supplement 2
This article is part of a Supplement: Volume 2 Supplement 2
This article is part of a Supplement: Volume 2 Supplement 2
This article is part of a Supplement: Volume 2 Supplement 2
This article is part of a Supplement: Volume 2 Supplement 2
This article is part of a Supplement: Volume 2 Supplement 2
This article is part of a Supplement: Volume 2 Supplement 2
This article is part of a Supplement: Volume 2 Supplement 2
This article is part of a Supplement: Volume 2 Supplement 2
This article is part of a Supplement: Volume 2 Supplement 2
This article is part of a Supplement: Volume 2 Supplement 2
This article is part of a Supplement: Volume 2 Supplement 2
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