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Mechanisms of suberoylanilide hydroxamic acid inhibition of mammary cell growth

The mechanism of suberoylanilide hydroxamic acid in cell growth inhibition involved induction of pRb-2/p130 interaction and nuclear translocation with E2F-4, followed by significant repression in E2F-1 and PCN...

Authors: Thenaa K Said, Ricardo CB Moraes, Raghu Sinha and Daniel Medina

Citation: Breast Cancer Research 2000 3:122

Content type: Research article Published on: 22 December 2000
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The cyclin dependent kinase inhibitor p27 and its prognostic role in breast cancer

p27 is an inhibitor of cyclin dependent kinase involved in the regulation of the cell cycle. In this commentary we discuss the current knowledge on p27 in breast cancer and its significance in predicting the o...

Authors: Roberto Chiarle, Michele Pagano and Giorgio Inghirami

Citation: Breast Cancer Research 2000 3:91

Content type: Commentary Published on: 20 December 2000
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Monoclonal antibodies targeting cancer: 'magic bullets' or just the trigger?

The first monoclonal antibodies (mAbs) approved for cancer therapy are now in Phase II and III trials, but the critical mechanism(s) determining efficacy and response in patients are still largely undefined. B...

Authors: Suzanne A Eccles

Citation: Breast Cancer Research 2000 3:86

Content type: Commentary Published on: 20 December 2000
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From Bittner to Barr: a viral, diet and hormone breast cancer aetiology hypothesis

It is hypothesized that the human homologue of the mouse mammary tumour virus (HHMMTV) and other viruses, such as human papillomavirus (HPV) and Epstein-Barr virus (EBV), act as cofactors with diet, oestrogens...

Authors: James S Lawson, Dinh Tran and William D Rawlinson

Citation: Breast Cancer Research 2000 3:81

Content type: Commentary Published on: 18 December 2000
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Molecular profiling of breast cancer: portraits but not physiognomy

Breast cancers differ in response to treatment and may have a divergent clinical course despite having a similar histopathological appearance. New technology using DNA microarrays provides a systematic method ...

Authors: James D Brenton, Samuel AJR Aparicio and Carlos Caldas

Citation: Breast Cancer Research 2000 3:77

Content type: Commentary Published on: 18 December 2000
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Ang1 in breast cancer

Authors: Valerie Speirs

Citation: Breast Cancer Research 2000 3:66719

Content type: Paper Report Published on: 1 December 2000
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Nuclear cytometric changes in breast carcinogenesis

Authors: Syed Mohsin

Citation: Breast Cancer Research 2000 3:66716

Content type: Paper Report Published on: 1 December 2000
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c-erbB2 homodimerisation in mammary epithelial cells

Authors: Jenny Gomm

Citation: Breast Cancer Research 2000 3:66715

Content type: Paper Report Published on: 1 December 2000
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Pathologic features associated with nonsentinel lymph node metastasis

Authors: Rodolfo Laucirica

Citation: Breast Cancer Research 2000 3:66714

Content type: Paper Report Published on: 1 December 2000
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ER variants in breast cancer

Authors: Valerie Speirs

Citation: Breast Cancer Research 2000 3:66713

Content type: Paper Report Published on: 1 December 2000
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HOXA5 regulation of p53 in breast tumours

Authors: Chris Jones

Citation: Breast Cancer Research 2000 3:66711

Content type: Paper Report Published on: 1 December 2000
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APCgene mutations in human breast cancers

Authors: Chris Jones

Citation: Breast Cancer Research 2000 3:66710

Content type: Paper Report Published on: 1 December 2000
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Chromosome 6 alterations

Authors: Chris Jones

Citation: Breast Cancer Research 2000 3:66709

Content type: Paper Report Published on: 1 December 2000
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Estrogen receptor β in breast cancer

Authors: Balvinder Shoker

Citation: Breast Cancer Research 2000 3:66708

Content type: Paper Report Published on: 1 December 2000
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Microdissection and microarrays

Authors: Mike Davies

Citation: Breast Cancer Research 2000 3:66707

Content type: Paper Report Published on: 1 December 2000
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Marker of increased cancer risk in benign breast disease

Authors: Jenny Chang

Citation: Breast Cancer Research 2000 3:66706

Content type: Paper Report Published on: 1 December 2000
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Amplification at 17q23 in breast cancer

Authors: Chris Jones

Citation: Breast Cancer Research 2000 2:66704

Content type: Paper Report Published on: 1 December 2000
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Clusterin in human breast cancer

Authors: Syed Mohsin

Citation: Breast Cancer Research 2000 2:66699

Content type: Paper Report Published on: 1 December 2000
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Loss of heterozygosity in fibrocystic change

Authors: Chris Jones

Citation: Breast Cancer Research 2000 2:66693

Content type: Paper Report Published on: 1 December 2000
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Com-1 in breast cancer

Authors: Valerie Speirs

Citation: Breast Cancer Research 2000 2:66691

Content type: Paper Report Published on: 1 December 2000
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Breast conserving therapy vs mastectomy for larger tumours

Authors: Emily Banks

Citation: Breast Cancer Research 2000 2:66690

Content type: Paper Report Published on: 1 December 2000
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Mammaglobin as a marker in breast cancer

Authors: Valerie Speirs

Citation: Breast Cancer Research 2000 2:66689

Content type: Paper Report Published on: 1 December 2000
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14-3-3σ down-modulation: a ubiquitous marker for breast cancer?

Authors: Karen Schmeichel

Citation: Breast Cancer Research 2000 2:66683

Content type: Paper Report Published on: 1 December 2000
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Genetic alterations in breast stroma may influence epithelial neoplasia

Authors: Jenny Gomm

Citation: Breast Cancer Research 2000 2:66681

Content type: Paper Report Published on: 1 December 2000
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Tamoxifen-resistant breast carcinoma xenograft

Authors: Valerie Speirs

Citation: Breast Cancer Research 2000 2:66679

Content type: Paper Report Published on: 1 December 2000
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Comparative rat and human mammary histopathology

Authors: Valerie Speirs

Citation: Breast Cancer Research 2000 2:66678

Content type: Paper Report Published on: 1 December 2000
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Tamoxifen and response

Authors: Valerie Speirs

Citation: Breast Cancer Research 2000 2:66676

Content type: Paper Report Published on: 1 December 2000
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CpG island methylation

Authors: Chris Jones

Citation: Breast Cancer Research 2000 2:66675

Content type: Paper Report Published on: 1 December 2000
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Beta-catenin in breast cancer

Authors: Valerie Speirs

Citation: Breast Cancer Research 2000 2:66674

Content type: Paper Report Published on: 1 December 2000
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ErbB2 and cell cycle control

Authors: Chris Jones

Citation: Breast Cancer Research 2000 2:66670

Content type: Paper Report Published on: 1 December 2000
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Molecular profiling

Authors: Chris Jones

Citation: Breast Cancer Research 2000 2:66668

Content type: Paper Report Published on: 1 December 2000
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Mammary pathology of genetically engineered mice

Authors: Beatrice Howard

Citation: Breast Cancer Research 2000 2:66666

Content type: Paper Report Published on: 1 December 2000
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C/EBPβ and mammary epithelial cell fate

Authors: Rob Clarke

Citation: Breast Cancer Research 2000 2:66664

Content type: Paper Report Published on: 1 December 2000
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SUM-159PT: an ER-independent breast cancer model

Authors: Valerie Speirs

Citation: Breast Cancer Research 2000 2:66660

Content type: Paper Report Published on: 1 December 2000
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Mammographic prediction of early breast cancer survival

Authors: Jenny McCann

Citation: Breast Cancer Research 2000 2:66658

Content type: Paper Report Published on: 1 December 2000
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ErbB-receptors in antiestrogen resistance

Authors: Valerie Speirs

Citation: Breast Cancer Research 2000 2:66654

Content type: Paper Report Published on: 1 December 2000
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ERBB2detection and associated chromosomal alterations

Authors: Chris Jones

Citation: Breast Cancer Research 2000 2:66652

Content type: Paper Report Published on: 1 December 2000
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HRT and the efficacy of mammographic screening for breast cancer

Authors: Emily Banks

Citation: Breast Cancer Research 2000 2:66651

Content type: Paper Report Published on: 1 December 2000
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Racial differences in breast carcinoma

Authors: Balvinder Shoker

Citation: Breast Cancer Research 2000 2:66650

Content type: Paper Report Published on: 1 December 2000
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Molecular cytogenetic analysis of breast cancer cell lines

Authors: Valerie Speirs

Citation: Breast Cancer Research 2000 2:66648

Content type: Paper Report Published on: 1 December 2000
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Truncated BRCA2 is cytoplasmic

Authors: David Bertwistle

Citation: Breast Cancer Research 2000 2:66647

Content type: Paper Report Published on: 1 December 2000
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Breast Cancer Menu

Authors: Lisa Hutchinson

Citation: Breast Cancer Research 2000 2:0016

Content type: Web Report Published on: 1 December 2000
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Freedom of information

Authors: Andrew McLaughlin

Citation: Breast Cancer Research 2000 2:0015

Content type: Web Report Published on: 1 December 2000
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metaRegister of Controlled Trials

Authors: Sarah Burrows

Citation: Breast Cancer Research 2000 2:0014

Content type: Web Report Published on: 1 December 2000
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Breast Cancer On-line

Authors: Lisa Hutchinson

Citation: Breast Cancer Research 2000 2:0013

Content type: Web Report Published on: 1 December 2000
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Biology of the Mammary Gland

Authors: Lesley Ponton

Citation: Breast Cancer Research 2000 2:0011

Content type: Web Report Published on: 1 December 2000
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Breast cancer gene linkage research network

Authors: JC Lyford BSc

Citation: Breast Cancer Research 2000 2:0009

Content type: Web Report Published on: 1 December 2000
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Free access to pathology images and expert opinion

Authors: JC Lyford

Citation: Breast Cancer Research 2000 2:0007

Content type: Web Report Published on: 1 December 2000
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A comprehensive patient information resource

Authors: JC Lyford

Citation: Breast Cancer Research 2000 2:0005

Content type: Web Report Published on: 1 December 2000
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Breast Cancer on CancerNet

Authors: Rachel Platt

Citation: Breast Cancer Research 2000 2:0001

Content type: Web Report Published on: 1 December 2000
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