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Polymorphic repeat in AIB1 does not alter breast cancer risk

We assessed the association between a glutamine repeat polymorphism in AIB1 and breast cancer risk in a case-control study (464 cases, 624 controls) nested within the Nurses' Health Study cohort. We observed no a...

Authors: Christopher A Haiman, Susan E Hankinson, Donna Spiegelman, Graham A Colditz, Walter C Willett, Frank E Speizer, Myles Brown and David J Hunter

Citation: Breast Cancer Research 2000 2:378

Content type: Research article Published on: 1 October 2000
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Estrogen receptor transcription and transactivation Basic aspects of estrogen action

Estrogen signaling has turned out to be much more complex and exciting than previously thought; the paradigm shift in our understanding of estrogen action came in 1996, when the presence of a new estrogen rece...

Authors: Stefan Nilsson and Jan-Åke Gustafsson

Citation: Breast Cancer Research 2000 2:360

Content type: Review Published on: 1 October 2000
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Estrogen receptor transcription and transactivation Structure-function relationship in DNA- and ligand-binding domains of estrogen receptors

Estrogen receptors are members of the nuclear receptor steroid family that exhibit specific structural features, ligand-binding domain sequence identity and dimeric interactions, that single them out. The crys...

Authors: Marc Ruff, Monique Gangloff, Jean Marie Wurtz and Dino Moras

Citation: Breast Cancer Research 2000 2:353

Content type: Review Published on: 1 October 2000
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Estrogen receptor transcription and transactivation Estrogen receptor knockout mice: what their phenotypes reveal about mechanisms of estrogen action

Natural, synthetic and environmental estrogens have numerous effects on the development and physiology of mammals. Estrogen is primarily known for its role in the development and functioning of the female repr...

Authors: Sylvia Curtis Hewitt, John F Couse and Kenneth S Korach

Citation: Breast Cancer Research 2000 2:345

Content type: Review Published on: 1 October 2000
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Estrogen receptor transcription and transactivation Estrogen receptor alpha and estrogen receptor beta: regulation by selective estrogen receptor modulators and importance in breast cancer

Estrogens display intriguing tissue-selective action that is of great biomedical importance in the development of optimal therapeutics for the prevention and treatment of breast cancer, for menopausal hormone ...

Authors: Benita S Katzenellenbogen and John A Katzenellenbogen

Citation: Breast Cancer Research 2000 2:335

Content type: Review Published on: 1 October 2000
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Nontransgenic models of breast cancer

Numerous models have been developed to address key elements in the biology of breast cancer development and progression. No model is ideal, but the most useful are those that reflect the natural history and hi...

Authors: Gloria H Heppner, Fred R Miller and PV Malathy Shekhar

Citation: Breast Cancer Research 2000 2:331

Content type: Commentary Published on: 1 October 2000
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Role of BRCAgene dysfunction in breast and ovarian cancer predisposition

Tumor suppressor genes that perform apparently generic cellular functions nonetheless cause tissue-specific syndromes in the human population when they are mutated in the germline. The two major hereditary bre...

Authors: Ralph Scully

Citation: Breast Cancer Research 2000 2:324

Content type: Commentary Published on: 1 October 2000
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Metastases: the glycan connection

An association between protein glycosylation and tumorigenesis has been recognized for over 10 years. Associations linking the importance of glycosylation events to tumor biology, especially the progression to...

Authors: Christine Couldrey and Jeffrey E Green

Citation: Breast Cancer Research 2000 2:321

Content type: Commentary Published on: 1 October 2000
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Quality management systems: the benefits of achieving ISO 9002

Authors: M Wheaton, S Munslow and MG Wallis

Citation: Breast Cancer Research 2000 2(Suppl 2):A69

Content type: Meeting abstract Published on: 1 October 2000

This article is part of a Supplement: Volume 2 Supplement 2
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Comparison of four methods of presentation of breast specimens

Authors: PA Thompson

Citation: Breast Cancer Research 2000 2(Suppl 2):A67

Content type: Meeting abstract Published on: 1 October 2000

This article is part of a Supplement: Volume 2 Supplement 2
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An evaluation of the relationship between compressed breast thickness and glandular dose, within the breast screening service

Authors: S Simpson

Citation: Breast Cancer Research 2000 2(Suppl 2):A65

Content type: Meeting abstract Published on: 1 October 2000

This article is part of a Supplement: Volume 2 Supplement 2
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Scenic screening sites of Sussex

Authors: V Repose

Citation: Breast Cancer Research 2000 2(Suppl 2):A63

Content type: Meeting abstract Published on: 1 October 2000

This article is part of a Supplement: Volume 2 Supplement 2
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What is the predictive value for malignancy of radiological classification for indeterminate microcalcification seen on mammography?

Authors: G Ralleigh, E Sanderson, GA Berjawi, MJ Michell, S Bose and S Henderson

Citation: Breast Cancer Research 2000 2(Suppl 2):A62

Content type: Meeting abstract Published on: 1 October 2000

This article is part of a Supplement: Volume 2 Supplement 2
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A radiographer's perspective of sentinel lymph node biopsy

Authors: SD Pendry

Citation: Breast Cancer Research 2000 2(Suppl 2):A61

Content type: Meeting abstract Published on: 1 October 2000

This article is part of a Supplement: Volume 2 Supplement 2
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Galactoductography

Authors: MN Mwangi

Citation: Breast Cancer Research 2000 2(Suppl 2):A59

Content type: Meeting abstract Published on: 1 October 2000

This article is part of a Supplement: Volume 2 Supplement 2
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Pictorial essay of fat necrosis

Authors: A Murphy and JR Smales

Citation: Breast Cancer Research 2000 2(Suppl 2):A58

Content type: Meeting abstract Published on: 1 October 2000

This article is part of a Supplement: Volume 2 Supplement 2
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Audit rules OK! The benefits of an internal quality audit programme in the breast screening service

Authors: S Munslow and MG Wallis

Citation: Breast Cancer Research 2000 2(Suppl 2):A57

Content type: Meeting abstract Published on: 1 October 2000

This article is part of a Supplement: Volume 2 Supplement 2
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Imaging methods to screen women with breast implants

Authors: M Morrow

Citation: Breast Cancer Research 2000 2(Suppl 2):A56

Content type: Meeting abstract Published on: 1 October 2000

This article is part of a Supplement: Volume 2 Supplement 2
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Flexible screening clinics: future options

Authors: SA Dyson and VA Milnes

Citation: Breast Cancer Research 2000 2(Suppl 2):A54

Content type: Meeting abstract Published on: 1 October 2000

This article is part of a Supplement: Volume 2 Supplement 2
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Latent image fade and Kodak MinR2000 film

Authors: A Cowley and V Gilks

Citation: Breast Cancer Research 2000 2(Suppl 2):A52

Content type: Meeting abstract Published on: 1 October 2000

This article is part of a Supplement: Volume 2 Supplement 2
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Technical recalls (TC): a lesser service?

Authors: B Caswell and V Gilks

Citation: Breast Cancer Research 2000 2(Suppl 2):A50

Content type: Meeting abstract Published on: 1 October 2000

This article is part of a Supplement: Volume 2 Supplement 2
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Image blur: back to basics

Authors: J Berry-Smith and C Lonsdale

Citation: Breast Cancer Research 2000 2(Suppl 2):A48

Content type: Meeting abstract Published on: 1 October 2000

This article is part of a Supplement: Volume 2 Supplement 2
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Up the creek without a paddle

Authors: G Baxter

Citation: Breast Cancer Research 2000 2(Suppl 2):A46

Content type: Meeting abstract Published on: 1 October 2000

This article is part of a Supplement: Volume 2 Supplement 2
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Prediction of the underlying histology from the mammogram: mammographic-large section histologic correlation of >1000 open surgical biopsies

Authors: L Tabár

Citation: Breast Cancer Research 2000 2(Suppl 2):A44

Content type: Meeting abstract Published on: 1 October 2000

This article is part of a Supplement: Volume 2 Supplement 2
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Assessing an individual's film reading ability

Authors: A Gale

Citation: Breast Cancer Research 2000 2(Suppl 2):A42

Content type: Meeting abstract Published on: 1 October 2000

This article is part of a Supplement: Volume 2 Supplement 2
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Comments from a breast clinician

Authors: EMC Denton

Citation: Breast Cancer Research 2000 2(Suppl 2):A40

Content type: Meeting abstract Published on: 1 October 2000

This article is part of a Supplement: Volume 2 Supplement 2
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Computer aided detection

Authors: PM Taylor

Citation: Breast Cancer Research 2000 2(Suppl 2):A35

Content type: Meeting abstract Published on: 1 October 2000

This article is part of a Supplement: Volume 2 Supplement 2
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Using new technology to achieve the ideal mammogram

Authors: KC Young

Citation: Breast Cancer Research 2000 2(Suppl 2):A33

Content type: Meeting abstract Published on: 1 October 2000

This article is part of a Supplement: Volume 2 Supplement 2
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The technical aspects of adapting add-on digital stereotactic equipment for use with patient lying horizontally

Authors: G Rubin, R Evans and A Page

Citation: Breast Cancer Research 2000 2(Suppl 2):A31

Content type: Meeting abstract Published on: 1 October 2000

This article is part of a Supplement: Volume 2 Supplement 2
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Breast ultrasound in a "moderate risk" population

Authors: D O'Driscoll, R Warren, J MacKay, P Britton and NE Day

Citation: Breast Cancer Research 2000 2(Suppl 2):A29

Content type: Meeting abstract Published on: 1 October 2000

This article is part of a Supplement: Volume 2 Supplement 2
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Sclerosing lymphocytic lobulitis (SLL): a diagnostic challenge

Authors: S Dutta, L Campbell, RM Watkins, C Teasdale, DM Lee and PA Jones

Citation: Breast Cancer Research 2000 2(Suppl 2):A27

Content type: Meeting abstract Published on: 1 October 2000

This article is part of a Supplement: Volume 2 Supplement 2
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Can radiographers reliably read screening mammograms?

Authors: G Wivell, I Harvey, J Curtin and E Denton

Citation: Breast Cancer Research 2000 2(Suppl 2):A25

Content type: Meeting abstract Published on: 1 October 2000

This article is part of a Supplement: Volume 2 Supplement 2
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The early impact of the breast cancer screening programme in the city of Florence: methods of evaluation and first results (1990-1996)

Authors: E Paci, D Giorgi, M Zappa, C Seghieri and M Rosselli del Turco

Citation: Breast Cancer Research 2000 2(Suppl 2):A23

Content type: Meeting abstract Published on: 1 October 2000

This article is part of a Supplement: Volume 2 Supplement 2
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How long does it take to become a competent mammographer?

Authors: SM Naylor

Citation: Breast Cancer Research 2000 2(Suppl 2):A22

Content type: Meeting abstract Published on: 1 October 2000

This article is part of a Supplement: Volume 2 Supplement 2
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Stages of screen-detected breast cancer

Authors: K Koufopoulos, I Garas, Ch Pateras, E Ampatzoglou, P Kakavoulis, A Michas, S Gravas, V Sarrou, D Tsitsimelis, M Tsompanlioti, N Papageorgiou, K Kapridaki and F De Waard

Citation: Breast Cancer Research 2000 2(Suppl 2):A21

Content type: Meeting abstract Published on: 1 October 2000

This article is part of a Supplement: Volume 2 Supplement 2
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How do radiographers compare to radiologists when double reading screening mammograms

Authors: J Inglis, J Curtis, C Eve, G Wivell, E Denton and G Hurst

Citation: Breast Cancer Research 2000 2(Suppl 2):A20

Content type: Meeting abstract Published on: 1 October 2000

This article is part of a Supplement: Volume 2 Supplement 2
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Radiological review of interval cancers in an Australian mammographic screening programme

Authors: J Cawson, AF Amos and AM Kavanagh

Citation: Breast Cancer Research 2000 2(Suppl 2):A18

Content type: Meeting abstract Published on: 1 October 2000

This article is part of a Supplement: Volume 2 Supplement 2
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A comparison of prone breast biopsy procedures using a digital imaging system with a conventional upright technique

Authors: Z Vegnuti and M Whall

Citation: Breast Cancer Research 2000 2(Suppl 2):A17

Content type: Meeting abstract Published on: 1 October 2000

This article is part of a Supplement: Volume 2 Supplement 2
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Preoperative detection of multicentric breast cancer using tetrafosmin mammoscintigraphy

Authors: S Varkey, MJ Smith and PJ Cant

Citation: Breast Cancer Research 2000 2(Suppl 2):A16

Content type: Meeting abstract Published on: 1 October 2000

This article is part of a Supplement: Volume 2 Supplement 2
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The evaluation of four small-field digital mammography systems

Authors: CP Lawinski, D Smith, DS Evans, A Mackenzie, NSA Wells, D Emerton and CA Lewis

Citation: Breast Cancer Research 2000 2(Suppl 2):A14

Content type: Meeting abstract Published on: 1 October 2000

This article is part of a Supplement: Volume 2 Supplement 2
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Pre-operative diagnosis and staging of symptomatic breast disease using ^99mtechnitium scintimammography

Authors: I Bradford, A Mackie, E McCauley, P Cadigan and A Cook

Citation: Breast Cancer Research 2000 2(Suppl 2):A12

Content type: Meeting abstract Published on: 1 October 2000

This article is part of a Supplement: Volume 2 Supplement 2
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Surgical management

Authors: JM Dixon

Citation: Breast Cancer Research 2000 2(Suppl 2):A9

Content type: Meeting abstract Published on: 1 October 2000

This article is part of a Supplement: Volume 2 Supplement 2
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MR-guided breast biopsy

Authors: SH Heywang-Köbrunner, H Sittek, X Prat and L Baath

Citation: Breast Cancer Research 2000 2(Suppl 2):A7

Content type: Meeting abstract Published on: 1 October 2000

This article is part of a Supplement: Volume 2 Supplement 2
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The Swedish Two-County Trial 20-years on: updated mortality results and new insights from long-term follow-up

Authors: L Tabár, SW Duffy, B Viták, H-H Chen and UB Krusemo

Citation: Breast Cancer Research 2000 2(Suppl 2):A3

Content type: Meeting abstract Published on: 1 October 2000

This article is part of a Supplement: Volume 2 Supplement 2
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Future possibilities in the prevention of breast cancer: Luteinizing hormone-releasing hormone agonists

The cyclic production of estrogen and progesterone by the premenopausal ovary accounts for the steep rise in breast cancer risk in premenopausal women. These hormones are breast cell mitogens. By reducing expo...

Authors: Darcy V Spicer and Malcolm C Pike

Citation: Breast Cancer Research 2000 2:264

Content type: Review Published on: 1 August 2000
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Future possibilities in the prevention of breast cancer: Breast cancer prevention trials

The available results from breast cancer chemoprevention trials are reviewed. Four trials using tamoxifen have been performed, of which three have reported efficacy results. A fifth trial using raloxifene has ...

Authors: Jack Cuzick

Citation: Breast Cancer Research 2000 2:258

Content type: Review Published on: 1 August 2000
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Mammographic screening and mammographic patterns

Mammography is an effective screening modality for the early detection of breast cancer. The reduction in breast cancer mortality is greater for women aged over 50 at screening than for women aged under 50. Ma...

Authors: Nick Day and Ruth Warren

Citation: Breast Cancer Research 2000 2:247

Content type: Commentary Published on: 1 August 2000
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Acetyltransferases and tumour suppression

The acetyltransferase p300 was first identified associated with the adenoviral transforming protein E1A, suggesting a potential role for p300 in the regulation of cell proliferation. Direct evidence demonstrat...

Authors: Andrew C Phillips and Karen H Vousden

Citation: Breast Cancer Research 2000 2:244

Content type: Commentary Published on: 1 August 2000
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New hurdles for translational research

New guidelines for the collection and use of human tissues for research will impose new requirements on researchers to seek ethical approval and patient consent. This extends to the use of surplus tissue, such...

Authors: Mitch Dowsett

Citation: Breast Cancer Research 2000 2:241

Content type: Commentary Published on: 1 August 2000
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Utilization of human tissue in breast cancer research

The use of human tissue, and material derived from such tissue, for research purposes is currently the subject of much debate. This debate needs to address several issues, including: the principle of abandonme...

Authors: Wendy Prime, Mark E Sobel and C Simon Herrington

Citation: Breast Cancer Research 2000 2:237

Content type: Commentary Published on: 1 August 2000
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