Volume 5 Supplement 1

24th Congress of the International Association for Breast Cancer Research. Advances in human breast cancer research: preclinical models

Meeting abstracts

24th Congress of the International Association for Breast Cancer Research. Advances in human breast cancer research: preclinical models.

Sacramento, USA1-5 November 2003

Page 1 of 2

Mouse models of human breast cancer: evolution or convolution?

Authors: JE Green

Citation: Breast Cancer Research 2003 5(Suppl 1):1

Content type: Oral presentation Published on: 1 October 2003
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Estrogen receptor alpha-positive and negative mouse mammary tumors through somatic mutations of p53 in mammary carcinogenesis

Authors: S-CJ Lin, K-F Lee, AY Nikitin, KM Bushnell, SG Hilsenbeck, RD Cardiff, A Li, K-W Kang, SA Frank, W-H Lee and EY-HP Lee

Citation: Breast Cancer Research 2003 5(Suppl 1):2

Content type: Oral presentation Published on: 1 October 2003
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Mouse models for BRCA1-associated breast cancer

Authors: R-H Wang, W Li, X Xu and C Deng

Citation: Breast Cancer Research 2003 5(Suppl 1):3

Content type: Oral presentation Published on: 1 October 2003
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Integrin-mediated signal transduction in transgenic mouse models of human breast cancer

Authors: DE White, S Blaess, U Mueller, S Dedhar, RD Cardiff, R St Arnaud and WJ Muller

Citation: Breast Cancer Research 2003 5(Suppl 1):4

Content type: Oral presentation Published on: 1 October 2003
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Reversibility and progression in conditional transgenic mouse models of breast cancer

Authors: LA Chodosh, RB Boxer, SE Moody, BA Keister, CJ Sarkisian, JW Jang, GK Belka, CM Blakely, CP Portocarero, CJ Sterner, KL Notarfrancesco and EA Kauh

Citation: Breast Cancer Research 2003 5(Suppl 1):5

Content type: Oral presentation Published on: 1 October 2003
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Genetic manipulation of the mammary gland by transplantation

Authors: P Edwards

Citation: Breast Cancer Research 2003 5(Suppl 1):6

Content type: Oral presentation Published on: 1 October 2003
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The Mutant Mouse Regional Resource Center Program

Authors: KCK Lloyd

Citation: Breast Cancer Research 2003 5(Suppl 1):7

Content type: Oral presentation Published on: 1 October 2003
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Genetically altered mice and cancer research: effects of the other 99.999% of the genome and other variables upon phenotype

Authors: SW Barthold

Citation: Breast Cancer Research 2003 5(Suppl 1):8

Content type: Oral presentation Published on: 1 October 2003
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Advanced immunophenotyping: more is better!

Authors: N Baumgarth

Citation: Breast Cancer Research 2003 5(Suppl 1):9

Content type: Oral presentation Published on: 1 October 2003
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Whole Slide Imaging and telepathology

Authors: J Galvez

Citation: Breast Cancer Research 2003 5(Suppl 1):10

Content type: Oral presentation Published on: 1 October 2003
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Mammary pathology of the genetically engineered mouse

Authors: AD Borowsky

Citation: Breast Cancer Research 2003 5(Suppl 1):11

Content type: Oral presentation Published on: 1 October 2003
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Positron emission tomography and X-ray computed tomography: tools for mouse phenotyping?

Authors: SR Cherry

Citation: Breast Cancer Research 2003 5(Suppl 1):12

Content type: Oral presentation Published on: 1 October 2003
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Genetically modified cancer models: the value of luciferase-tagged tumors and in vivo luciferase-based reporter assays in oncology drug discovery

Authors: W Yang, C Kowal, E Sorensen and P Lassota

Citation: Breast Cancer Research 2003 5(Suppl 1):13

Content type: Oral presentation Published on: 1 October 2003
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Herceptin-sensitivity of HER2-transgenic mouse mammary tumors

Authors: RH Schwall, P Hollingshead, S Erickson, J Winer, M Williams and D Dugger

Citation: Breast Cancer Research 2003 5(Suppl 1):14

Content type: Oral presentation Published on: 1 October 2003
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Role of animal models in oncology drug discovery

Authors: R Kumar

Citation: Breast Cancer Research 2003 5(Suppl 1):15

Content type: Oral presentation Published on: 1 October 2003
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Use of mouse models to validate and therapeutically target transforming growth factor beta as an important player in breast cancer progression

Authors: LM Wakefield, Y Yang, O Dukhanina, B Tang, M Mamura, JL Letterio, J Green, GT Merlino and MR Anver

Citation: Breast Cancer Research 2003 5(Suppl 1):16

Content type: Oral presentation Published on: 1 October 2003
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Development of a transgenic mouse line for the evaluation of the androgen receptor activity in vivo

Authors: R Attar, C Cullinan, C-P Ho, M Swerdel, J Dell, RB Rowley, DJ Bol, J Ostrowski, K Mookhtiar, M Gottardis and R Weinmann

Citation: Breast Cancer Research 2003 5(Suppl 1):17

Content type: Oral presentation Published on: 1 October 2003
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Clinical breast cancer and estrogen

Authors: HK Chew

Citation: Breast Cancer Research 2003 5(Suppl 1):18

Content type: Oral presentation Published on: 1 October 2003
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Pregnancy levels of estrogen prevents breast cancer

Authors: S Nandi, RC Guzman, G Thordarson and L Rajkumar

Citation: Breast Cancer Research 2003 5(Suppl 1):19

Content type: Oral presentation Published on: 1 October 2003
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Steroid regulation of breast cancer cell proliferation

Authors: RL Sutherland

Citation: Breast Cancer Research 2003 5(Suppl 1):20

Content type: Oral presentation Published on: 1 October 2003
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The ErbB receptor tyrosine kinases and their roles in cancer

Authors: NE Hynes

Citation: Breast Cancer Research 2003 5(Suppl 1):21

Content type: Oral presentation Published on: 1 October 2003
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Predicting breast cancer behavior by microarray analysis

Authors: M van de Vijver

Citation: Breast Cancer Research 2003 5(Suppl 1):22

Content type: Oral presentation Published on: 1 October 2003
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The molecular biology of mammary intraepithelial neoplasia outgrowths

Authors: L Namba, SY Liu, ET McGoldrick, LJT Young, AD Borowsky, RD Cardiff and JP Gregg

Citation: Breast Cancer Research 2003 5(Suppl 1):23

Content type: Oral presentation Published on: 1 October 2003
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The comparative genetics and genomics of cancer: of mice and men

Authors: G Hodgson, J Hager, K Chin, CA Lapuk, S Volik, C Collins, A Balmain, F Waldman, D Hanahan and J Gray

Citation: Breast Cancer Research 2003 5(Suppl 1):24

Content type: Oral presentation Published on: 1 October 2003
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Proof-of-concept in vivo evaluation of targeted therapeutics: lessons from immunoliposomes

Authors: CC Benz

Citation: Breast Cancer Research 2003 5(Suppl 1):25

Content type: Oral presentation Published on: 1 October 2003
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Synergy between the erbB and transforming growth factor beta signaling networks: implications for molecular therapeutics in human neoplasia

Authors: CL Arteaga

Citation: Breast Cancer Research 2003 5(Suppl 1):26

Content type: Oral presentation Published on: 1 October 2003
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The mouse in preclinical trials: transgenic, carcinogen-induced, or xenograph models – which to use?

Authors: P Brown

Citation: Breast Cancer Research 2003 5(Suppl 1):27

Content type: Oral presentation Published on: 1 October 2003
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Transgenic models are predictive: the herceptin and flavopiridol experience

Authors: E Schmidt

Citation: Breast Cancer Research 2003 5(Suppl 1):28

Content type: Oral presentation Published on: 1 October 2003
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Modeling breast cancer in the rat: a method to produce knockout rats

Authors: MN Gould

Citation: Breast Cancer Research 2003 5(Suppl 1):29

Content type: Oral presentation Published on: 1 October 2003
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Genetically engineered mouse models of human breast cancer

Authors: RA Jensen

Citation: Breast Cancer Research 2003 5(Suppl 1):30

Content type: Oral presentation Published on: 1 October 2003
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Role of differentiation in carcinogenesis and cancer prevention

Authors: J Russo and IH Russo

Citation: Breast Cancer Research 2003 5(Suppl 1):31

Content type: Oral presentation Published on: 1 October 2003
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Genetic determinants of susceptibility to estrogen-induced mammary cancer in the rat

Authors: JD Shull, BS Schaffer, LM Bartsch, LK Buckles, KA Gould, M Tochacek, B Xie, CM Lachel, KL Pennington, TE Strecker and KK Hansen

Citation: Breast Cancer Research 2003 5(Suppl 1):32

Content type: Oral presentation Published on: 1 October 2003
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Transforming growth factor β's role in mammary gland development and carcinogenesis

Authors: MH Barcellos-Hoff

Citation: Breast Cancer Research 2003 5(Suppl 1):33

Content type: Oral presentation Published on: 1 October 2003
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Hormonal interactions during mammary gland development

Authors: BK Vonderhaar

Citation: Breast Cancer Research 2003 5(Suppl 1):34

Content type: Oral presentation Published on: 1 October 2003
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Function of LEF1 in early mammary development

Authors: K Kratochwil, S Tontsch and R Grosschedl

Citation: Breast Cancer Research 2003 5(Suppl 1):35

Content type: Oral presentation Published on: 1 October 2003
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Expression profiling of breast cancer, influence of tumor genotype and patient genotype

Authors: A-L Borresen-Dale

Citation: Breast Cancer Research 2003 5(Suppl 1):36

Content type: Oral presentation Published on: 1 October 2003
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Germline mutations in DNA repair and cell cycle checkpoint genes: consequential somatic gene alterations and genome instability

Authors: S Ingvarsson

Citation: Breast Cancer Research 2003 5(Suppl 1):37

Content type: Oral presentation Published on: 1 October 2003
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Using genomic similarities and differences to interpret mouse models of human development and cancer

Authors: L Stubbs, C Elso, G Loots, A Hamilton and I Ovcharenko

Citation: Breast Cancer Research 2003 5(Suppl 1):38

Content type: Oral presentation Published on: 1 October 2003
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A hybrid functional/anatomical imaging system for high-throughput planar projection mouse imaging

Authors: JM Boone and K Yang

Citation: Breast Cancer Research 2003 5(Suppl 1):39

Content type: Oral presentation Published on: 1 October 2003
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Imaging mouse models of breast cancer with positron emission tomography

Authors: S Cherry, C Abbey, S Borowsky, J Gregg and R Cardiff

Citation: Breast Cancer Research 2003 5(Suppl 1):40

Content type: Oral presentation Published on: 1 October 2003
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Imaging angiogenesis in early stages of breast cancer using a standardized radiolabeled adapter protein docked to vascular endothelial growth factor

Authors: S Mandl, FG Blankenberg, Y-A Cao, C O'Connell-Rodwell, C Mari, TI Gaynutdinov, J-L Vanderheyden, MV Backer, JM Backer and C Contag

Citation: Breast Cancer Research 2003 5(Suppl 1):41

Content type: Oral presentation Published on: 1 October 2003
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Ultrasound imaging of tumor perfusion

Authors: K Ferrara, P Dayton, R Pollard, A Broumas and E Wisner

Citation: Breast Cancer Research 2003 5(Suppl 1):42

Content type: Oral presentation Published on: 1 October 2003
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Advanced imaging and detection R&D in the Center for Biophotonics

Authors: DL Matthews

Citation: Breast Cancer Research 2003 5(Suppl 1):43

Content type: Oral presentation Published on: 1 October 2003
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Preneoplasia in mouse models

Authors: D Medina

Citation: Breast Cancer Research 2003 5(Suppl 1):44

Content type: Oral presentation Published on: 1 October 2003
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Mammary intraepithelial neoplasia outgrowths (MINO): MINO and human ductal carcinoma in situ

Authors: AD Borowsky

Citation: Breast Cancer Research 2003 5(Suppl 1):45

Content type: Oral presentation Published on: 1 October 2003
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Premalignancy in the human breast: how is it defined, is morphology good enough?

Authors: BA Gusterson

Citation: Breast Cancer Research 2003 5(Suppl 1):46

Content type: Oral presentation Published on: 1 October 2003
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In situ to invasive carcinoma transition: escape or release

Authors: K Polyak

Citation: Breast Cancer Research 2003 5(Suppl 1):47

Content type: Oral presentation Published on: 1 October 2003
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Regulation of human mammary stem cells

Authors: RB Clarke, E Anderson, A Howell, H Okano and CS Potten

Citation: Breast Cancer Research 2003 5(Suppl 1):48

Content type: Oral presentation Published on: 1 October 2003
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Characterization, isolation and cultivation of distinctive human breast cell populations

Authors: R Villadsen, T Gudjonsson, A Fridriksdottir, M Wissing, L Rønnov-Jessen, MJ Bissell and OW Petersen

Citation: Breast Cancer Research 2003 5(Suppl 1):49

Content type: Oral presentation Published on: 1 October 2003
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Stem cells in normal breast development and breast cancer

Authors: MS Wicha, G Dontu, M Al-Hajj and MF Clarke

Citation: Breast Cancer Research 2003 5(Suppl 1):50

Content type: Oral presentation Published on: 1 October 2003
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24th Congress of the International Association for Breast Cancer Research. Advances in human breast cancer research: preclinical models

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