Volume 5 Supplement 1

24th Congress of the International Association for Breast Cancer Research. Advances in human breast cancer research: preclinical models

Open Access

Clinical breast cancer and estrogen

  • HK Chew1
Breast Cancer Research20035(Suppl 1):18


Published: 1 October 2003

Endocrine therapy, targeting estrogen production or the estrogen receptor, is a crucial component in the treatment of breast cancer. This has been recognized for over a century. Ovarian ablation is the oldest form of endocrine therapy, first used in 1896. This presentation will review: the history of endocrine therapy in the treatment of breast cancer; endocrine strategies in premenopausal and postmenopausal women; data on the use of endocrine therapy in early breast cancer; new directions in the endocrine therapy of metastatic breast cancer; and clinical implications of HER2-neu status and endocrine therapy.

Authors’ Affiliations

UC Davis Cancer Center


© BioMed Central 2002