Volume 12 Supplement 1

Breast Cancer Research 2010

Meeting abstracts

Breast Cancer Research 2010. Go to conference site.

London, UK18 May 2010

Page 1 of 2

Tissue banking

Authors: WF Symmans

Citation: Breast Cancer Research 2010 12(Suppl 1):L1

Content type: Lecture presentation Published on: 18 May 2010
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Biomarkers for the diagnosis and prediction of therapeutic response in clinical breast cancer

Authors: J Bartlett

Citation: Breast Cancer Research 2010 12(Suppl 1):L2

Content type: Lecture presentation Published on: 18 May 2010
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Recent advances in treatment of metastatic breast cancer

Authors: R Coleman

Citation: Breast Cancer Research 2010 12(Suppl 1):L3

Content type: Lecture presentation Published on: 18 May 2010
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Male versus female breast cancer: a comparative study of 523 matched cases reveals differences behind similarity

Authors: V Speirs and G Ball

Citation: Breast Cancer Research 2010 12(Suppl 1):O1

Content type: Oral presentation Published on: 18 May 2010
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Upregulation of ADAM proteases and HER ligands through a feedback loop mediates acquired resistance to trastuzumab in HER2-amplified breast cancer

Authors: M Gijsen, P King, T Perera, P Parker, B Larijani, A Harris and A Kong

Citation: Breast Cancer Research 2010 12(Suppl 1):O2

Content type: Oral presentation Published on: 18 May 2010
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New regulators of the BRCA1 response to genotoxic stress

Authors: JR Morris, C Boutell, M Keppler, R Densham, D Weekes, A Alamshah, L Butler, Y Galanty, L Pangon, T Kiuchi, T Ng and E Solomon

Citation: Breast Cancer Research 2010 12(Suppl 1):O3

Content type: Oral presentation Published on: 18 May 2010
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DNA methylome of familial breast cancer identifies distinct profiles defined by mutation status

Authors: JM Flanagan, S Kugler, N Waddell, CN Johnstone, A Marsh, S Henderson, P Simpson, L da Silva, K Khanna, S Lakhani, C Boshoff and G Chenevix-Trench

Citation: Breast Cancer Research 2010 12(Suppl 1):O4

Content type: Oral presentation Published on: 18 May 2010
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Differentiation therapy: targeting breast cancer stem cells to reduce resistance to radiotherapy and chemotherapy

Authors: R Roy, PM Willan, R Clarke and G Farnie

Citation: Breast Cancer Research 2010 12(Suppl 1):O5

Content type: Oral presentation Published on: 18 May 2010
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Transforming growth factor-beta co-receptor endoglin suppresses breast cancer invasion and metastasis

Authors: LA Henry, DJ Johnson, S Lee, PR Quinlan, T Crook, AM Thompson, JS Reis-Filho and CM Isacke

Citation: Breast Cancer Research 2010 12(Suppl 1):O6

Content type: Oral presentation Published on: 18 May 2010
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Activin B functions downstream of BRCA1 in stem cell maintenance

Authors: MM Murray, N Buckley and DP Harkin

Citation: Breast Cancer Research 2010 12(Suppl 1):P1

Content type: Poster presentation Published on: 18 May 2010
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FOXM1 is a transcriptional target of ERα and has a critical role in breast cancer endocrine sensitivity and resistance

Authors: J Millour and EW Lam

Citation: Breast Cancer Research 2010 12(Suppl 1):P2

Content type: Poster presentation Published on: 18 May 2010
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A novel and selective PDK1 inhibitor reduces breast cancer cell invasion and tumour growth

Authors: C Raimondi, T Maffucci, BVL Potter and M Falasca

Citation: Breast Cancer Research 2010 12(Suppl 1):P3

Content type: Poster presentation Published on: 18 May 2010
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Regulation of mammary epithelial architecture by PTEN

Authors: JC Lim, L Davidson, NR Weerasinghe, G Zilidis, P Tibarewal, L Spinelli and NR Leslie

Citation: Breast Cancer Research 2010 12(Suppl 1):P4

Content type: Poster presentation Published on: 18 May 2010
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Genetic analysis of lobular carcinoma in situ and associated invasive lobular cancer

Authors: LR Yates, A Jones, H Patel, A Mackay, C Gillett, S Pinder, I Tomlinson, R Roylance and EJ Sawyer

Citation: Breast Cancer Research 2010 12(Suppl 1):P5

Content type: Poster presentation Published on: 18 May 2010
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Suppression of the NF-κB co-factor, Bcl3, delays the metastatic progression of breast cancer

Authors: AM Wakefield and RWE Clarkson

Citation: Breast Cancer Research 2010 12(Suppl 1):P6

Content type: Poster presentation Published on: 18 May 2010
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Identification of signalling pathways downstream of BRCA1 and p63

Authors: N Crawford, N Buckley, C Nic An tSaoir, D Tkocz, Z D'Costa, L Oram and P Mullan

Citation: Breast Cancer Research 2010 12(Suppl 1):P7

Content type: Poster presentation Published on: 18 May 2010
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D133P53, directly transactivated by p53, prevents p53-mediated apoptosis without inhibiting p53-mediated cell cycle arrest

Authors: M Aoubala, F Murray-Zmijewski, M Khoury, S Perrier, K Fernandes, AC Prats, D Lane and JC Bourdon

Citation: Breast Cancer Research 2010 12(Suppl 1):P8

Content type: Poster presentation Published on: 18 May 2010
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Loss of CSMD1 disrupts mammary epithelial morphogenesis

Authors: M Kamal, AM Shaaban, DL Holliday, C Toomes, V Speirs and SM Bell

Citation: Breast Cancer Research 2010 12(Suppl 1):P9

Content type: Poster presentation Published on: 18 May 2010
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Phosphoinositide 3-kinase class II beta is a novel target in breast cancer therapy

Authors: J Abbott, R Pineiro, MA Oliviero, R Lattanzio, M Piantelli, A Bilancio, T Maffucci and M Falasca

Citation: Breast Cancer Research 2010 12(Suppl 1):P10

Content type: Poster presentation Published on: 18 May 2010
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MicroRNA-92 targets the 3' untranslated region of ERβ1 mRNA and post-transcriptionally regulates its expression in breast cancer

Authors: HH Alnakhle, PA Burns, M Cummings, AM Hanby, TA Hughes, S Satheesha, AM Shaaban, L Smith and V Speirs

Citation: Breast Cancer Research 2010 12(Suppl 1):P11

Content type: Poster presentation Published on: 18 May 2010
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Regulation of the apoptotic genes in breast cancer cells by the transcription factor CTCF

Authors: CF Mendez-Catala, A Vostrov, E Pugacheva, Y Ito, F Docquier, I Chernukhin, D Farrar, G-X Kita, A Murrell, V Lobanankov and E Klenova

Citation: Breast Cancer Research 2010 12(Suppl 1):P12

Content type: Poster presentation Published on: 18 May 2010
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Fulvestrant-induced expression of erbB3 and erbB4 sensitizes ER-positive breast cancer cells to heregulins

Authors: IR Hutcheson, L Goddard, JMW Gee, D Barrow and RI Nicholson

Citation: Breast Cancer Research 2010 12(Suppl 1):P13

Content type: Poster presentation Published on: 18 May 2010
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Risks of contralateral breast cancer in BRCA1 and BRCA2 mutation carriers

Authors: M Ahmed, F Lalloo, A Howell and DG Evans

Citation: Breast Cancer Research 2010 12(Suppl 1):P14

Content type: Poster presentation Published on: 18 May 2010
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ADAMTS15 metalloproteinase inhibits breast cancer cell migration

Authors: L Wagstaff, R Kelwick, J Decock, H Arnold, C Pennington, D Jaworski and D Edwards

Citation: Breast Cancer Research 2010 12(Suppl 1):P15

Content type: Poster presentation Published on: 18 May 2010
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Macrophage-mediated breast cancer cell chemotaxis: the role of sphingosine kinase-1 activation

Authors: J Nunes, L Sauer, J Turner, J Waxman, J Sturge and D Pshezhetskiy

Citation: Breast Cancer Research 2010 12(Suppl 1):P16

Content type: Poster presentation Published on: 18 May 2010
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PLU-1/Jarid1B contributes to estrogen-induced cell proliferation in the normal mammary gland and in breast cancer, and is required for embryonic survival

Authors: S Catchpole, B Spencer-Dene, D Hall, A Scibetta, J Burchell and J Taylor-Papadimitriou

Citation: Breast Cancer Research 2010 12(Suppl 1):P17

Content type: Poster presentation Published on: 18 May 2010
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C-terminal binding proteins play a critical nuclear function in the mitotic fidelity of breast cancer cells

Authors: CN Birts and JP Blaydes

Citation: Breast Cancer Research 2010 12(Suppl 1):P18

Content type: Poster presentation Published on: 18 May 2010
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RhoBTB2 in breast cancer

Authors: CM McKinnon and H Mellor

Citation: Breast Cancer Research 2010 12(Suppl 1):P19

Content type: Poster presentation Published on: 18 May 2010
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Transcriptional regulation of cyclin-dependent kinase inhibitor 1A (P21) by the transcription factor AP-2γ

Authors: AG Scibetta, M Canosa and HC Hurst

Citation: Breast Cancer Research 2010 12(Suppl 1):P20

Content type: Poster presentation Published on: 18 May 2010
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Developmental protein HOXC11 cooperates with SRC-1 in breast cancer: an adaptive response to endocrine therapy

Authors: M McIlroy, D McCartan, S Early, S Pennington, P O'Gaora, A Hill and L Young

Citation: Breast Cancer Research 2010 12(Suppl 1):P21

Content type: Poster presentation Published on: 18 May 2010
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Insulin-like growth factor binding protein-2 alters the sensitivity of breast cancer cells to chemotherapy

Authors: EJ Foulstone, JM Holly, L Zeng, ZE Winters and CM Perks

Citation: Breast Cancer Research 2010 12(Suppl 1):P22

Content type: Poster presentation Published on: 18 May 2010
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Clinicopathologic and molecular predictors of axillary lymph node metastasis in early-stage breast cancer: a mathematical predictive model

Authors: MA Aleskandarany, AR Green, EA Rakha, SE Elsheikh, DG Powe, EC Paish and IO Ellis

Citation: Breast Cancer Research 2010 12(Suppl 1):P23

Content type: Poster presentation Published on: 18 May 2010
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Assessing the functional role of caspase-8 gene variants in breast cancer

Authors: SH Rigas, M Parry, MW Reed, N Camp and A Cox

Citation: Breast Cancer Research 2010 12(Suppl 1):P24

Content type: Poster presentation Published on: 18 May 2010
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Polymorphisms, endogenous hormone levels and familial breast cancer risk in premenopausal women

Authors: K Walker, O Fletcher, N Johnson, C Palles, E Folkerd, SG Hillier, S Moss, L Gibson, M Dowsett, J Peto and I dos santos Silva

Citation: Breast Cancer Research 2010 12(Suppl 1):P25

Content type: Poster presentation Published on: 18 May 2010
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A randomised controlled trial of the psychoneuroimmunological effects of reflexology in women with early-stage breast cancer

Authors: DM Sharp, MB Walker, A Chaturvedi, S Upadhyay, A Hamid, AA Walker, J Bateman, F Braid, K Ellwood, C Hebblewhite, T Hope, M Lines and LG Walker

Citation: Breast Cancer Research 2010 12(Suppl 1):P26

Content type: Poster presentation Published on: 18 May 2010
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An integrated informatics platform to facilitate transforming tissue into knowledge

Authors: PR Quinlan, A Ashfield, L Jordan, C Purdie and AM Thompson

Citation: Breast Cancer Research 2010 12(Suppl 1):P27

Content type: Poster presentation Published on: 18 May 2010
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Effect of intermittent versus continuous energy restriction on weight loss and breast cancer risk biomarkers

Authors: M Harvie, M Pegington, J Cuzick, J Frystyk, A Flyvbjerg, S Jebb, M Mattson and A Howell

Citation: Breast Cancer Research 2010 12(Suppl 1):P28

Content type: Poster presentation Published on: 18 May 2010
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Thioredoxin and related redox systems as targets in breast cancer

Authors: CM Woolston, L Zhang, H Evans, A Al-Attar, M Shehata, G Balls, SY Chan and SG Martin

Citation: Breast Cancer Research 2010 12(Suppl 1):P29

Content type: Poster presentation Published on: 18 May 2010
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Could side population cells be an indicator of progression to hormone nonresponsive breast cancer

Authors: KM Britton, IJ Harvey, K Stemke-Hale, TWJ Lennard and AP Meeson

Citation: Breast Cancer Research 2010 12(Suppl 1):P30

Content type: Poster presentation Published on: 18 May 2010
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A novel tumour-based test to identify breast cancer due to BRCA1 and BRCA2 mutations

Authors: Q An, L Jones, W Tapper, C Chelala, M Iravani, A MacKay, V Hammond, L Durcan, S Gerty, A Ferguson, J Strefford, S Peock, J Reis-Filho, D Easton, A Ashworth and D Eccles

Citation: Breast Cancer Research 2010 12(Suppl 1):P31

Content type: Poster presentation Published on: 18 May 2010
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Melanoma-associated antigen family protein-D4: clinical significance and functional relevance in breast cancer

Authors: S Germano, S Rani, S Kennedy, J Crown, M Clynes and L O'Driscoll

Citation: Breast Cancer Research 2010 12(Suppl 1):P32

Content type: Poster presentation Published on: 18 May 2010
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Identification of molecular subtypes within a formalin-fixed, paraffin-embedded breast cancer tumour cohort

Authors: JM Mulligan, F McDyer, S Deharo, V Farztdinov, I Halfpenny, T Delaney, F Couch, JE Quinn, P Harkin and R Kennedy

Citation: Breast Cancer Research 2010 12(Suppl 1):P33

Content type: Poster presentation Published on: 18 May 2010
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Evaluating gene expression in formalin-fixed, paraffin-embedded breast cancer tissues using DASL^®

Authors: T Burr, R Dixon, A Green, I Ellis and C Murray

Citation: Breast Cancer Research 2010 12(Suppl 1):P34

Content type: Poster presentation Published on: 18 May 2010
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miR-433 overexpression attenuates the spindle assembly checkpoint response to paclitaxel

Authors: F Furlong, M Prencipe, A McGoldrick, P McGettigan, D Carney, E Doyle, E Kay and A McCann

Citation: Breast Cancer Research 2010 12(Suppl 1):P35

Content type: Poster presentation Published on: 18 May 2010
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Breast calcification: the 'Cinderella' breast element?

Authors: KD Rogers, R Baker and N Stone

Citation: Breast Cancer Research 2010 12(Suppl 1):P36

Content type: Poster presentation Published on: 18 May 2010
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Expression of migration stimulating factor in breast tissues and its clinical significance

Authors: AM Schor, S Perrier, AM Woolston, SJ Jones, IR Ellis, MR Islam, S Kazmi, C Purdie, AM Thompson and SL Schor

Citation: Breast Cancer Research 2010 12(Suppl 1):P37

Content type: Poster presentation Published on: 18 May 2010
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Lack of correlation between markers of breast cancer initiating cells

Authors: Y Liu, PJ Coates, R Nenutil, MVCL Appleyard, K Murray and AM Thompson

Citation: Breast Cancer Research 2010 12(Suppl 1):P38

Content type: Poster presentation Published on: 18 May 2010
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Mitochondrial translocator protein modulates metabolism and pharmacologically induced apoptosis in breast cancer cells

Authors: A Gastaldello, P Gami, H Callaghan and M Campanella

Citation: Breast Cancer Research 2010 12(Suppl 1):P39

Content type: Poster presentation Published on: 18 May 2010
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Identification of proteins and signalling pathways involved in neoadjuvant chemotherapy responsiveness of breast tumours using proteomics

Authors: CR Greenwood, LC Alldridge, S Chandra Sekharan, K Al-Janabi, P Sauven and S Souchelnytskyi

Citation: Breast Cancer Research 2010 12(Suppl 1):P40

Content type: Poster presentation Published on: 18 May 2010
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Reduced MCPH1 expression in breast cancer and response to chemotherapy

Authors: J Richardson, A Shaaban, M Kamal, I Ellis, V Speirs, A Green and SM Bell

Citation: Breast Cancer Research 2010 12(Suppl 1):P41

Content type: Poster presentation Published on: 18 May 2010
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