Volume 2 Supplement 1

Second International Symposium on the Molecular Biology of Breast Cancer

Meeting abstracts

Second International Symposium on the Molecular Biology of Breast Cancer.

Lillehammer, Norway12-16 March 2000

Page 2 of 3

BRCA1, BRCA2 and pedigree genetic analysis to determine genetic risk in the UK Royal Marsden Hospital tamoxifen prevention trial

Authors: Z Kote-Jarai, TP Powles, S Ashley, DF Easton, L Assersohn, N Sodha, M Dowsett, B Gusterson, A Tidy, G Mitchell and RA Eeles

Citation: Breast Cancer Research 2000 2(Suppl 1):P1.06

Content type: Meeting abstract Published on: 12 March 2000
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Mutational analysis of BRCA1 and BRCA2 genes in Spanish women with early-onset breast cancer

Authors: JI Martínez-Ferrandis, A Vega, P Marín-Garcia, F Barros, FJ Chaves, A Carracedo, ME Armengod, I Chirivella, A Lluch, J García-Conde and A Cervantes

Citation: Breast Cancer Research 2000 2(Suppl 1):P1.07

Content type: Meeting abstract Published on: 12 March 2000
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One test to identify 50% of all Norwegian BRCA1 mutations

Authors: P Møller, E Hovig, K Lycke, RAP Stacy, OJ Dahlberg, A Hagen, B Hagen, K Løvslett, H Qvist and K Heimdal

Citation: Breast Cancer Research 2000 2(Suppl 1):P1.08

Content type: Meeting abstract Published on: 12 March 2000
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X chromosome inactivation pattern in female patients with breast cancer

Authors: M Kristiansen, A Langer, GP Knudsen, BL Weber, A-L Børresen-Dale and KH Ørstavik

Citation: Breast Cancer Research 2000 2(Suppl 1):P1.10

Content type: Meeting abstract Published on: 12 March 2000
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HRAS1 minisatellite alleles and breast cancer in Spanish women under age forty years

Authors: A Vega, JI Martínez, F Barros, P Marín-García, FJ Chavez, C Ruiz-Ponte, I Chirivella, A Lluch, A Cervantes, I García-Conde, ME Armengod and A Carracedo

Citation: Breast Cancer Research 2000 2(Suppl 1):P1.11

Content type: Meeting abstract Published on: 12 March 2000
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Mammary-specific targeting of the murine BRCA2 breast cancer susceptibility gene in mice

Authors: NK Collins, KA McAllister, LM Bennett, K-U Wagner, T Ward, J Malphurs, G Goulding, EM Eddy, BJ Davis and RW Wiseman

Citation: Breast Cancer Research 2000 2(Suppl 1):P1.16

Content type: Meeting abstract Published on: 12 March 2000
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Growth inhibition and growth stimulation by estradiol of estrogen receptor transfected human breast epithelial cell lines involve different pathways

Authors: BK Lundholt, P Briand and AE Lykkesfeldt

Citation: Breast Cancer Research 2000 2(Suppl 1):P2.02

Content type: Meeting abstract Published on: 12 March 2000
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Hairy and enhancer of split homolog-1 (HES-1) mediates the proliferative effect of Beta-estradiol on breast cancer cell lines

Authors: A Ström, N Arai, J Leers and J-Å Gustafsson

Citation: Breast Cancer Research 2000 2(Suppl 1):P2.03

Content type: Meeting abstract Published on: 12 March 2000
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Genetic variants of CYP19 (aromatase) and breast cancer risk

Authors: V Nedelcheva Kristensen, N Harada, N Yoshimura, E Haraldsen, PE Lønning, B Erikstein, R Kåresen, T Kristensen and A-L Børresen-Dale

Citation: Breast Cancer Research 2000 2(Suppl 1):P2.04

Content type: Meeting abstract Published on: 12 March 2000
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The involvement of the MAPK signalling pathway in the adaptation of MCF-7 cells to long-term oestrogen deprivation

Authors: L-A Martin, CMW Chan, C Marshall and M Dowsett

Citation: Breast Cancer Research 2000 2(Suppl 1):P2.05

Content type: Meeting abstract Published on: 12 March 2000
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IGFBP-7 expression in human breast cancer and association with proliferation and cell cycle aberrations

Authors: H Östlund, A Burger, A Seth and G Landberg

Citation: Breast Cancer Research 2000 2(Suppl 1):P3.02

Content type: Meeting abstract Published on: 12 March 2000
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Activation of the Her2/neu receptor leads to antiestrogen resistance, but acquired resistance is not caused by altered ErbB expression and activation

Authors: SS Larsen and AE Lykkesfeldt

Citation: Breast Cancer Research 2000 2(Suppl 1):P3.03

Content type: Meeting abstract Published on: 12 March 2000
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Factors modulating integrin Beta I expression on the breast cancer cell lines MCF-7 and MDA-MB-231

Authors: CJ Pogson, CMW Chan, L-A Martin, GPH Gui and M Dowsett

Citation: Breast Cancer Research 2000 2(Suppl 1):P3.06

Content type: Meeting abstract Published on: 12 March 2000
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HER-2 activation and TP53 inactivation as predictors of survival in breast cancer

Authors: TI Andersen, E Skovlund, IK Bukholm, U Jacobsen, R Kåresen, B Erikstein, J Nesland and A-L Børresen-Dale

Citation: Breast Cancer Research 2000 2(Suppl 1):P3.07

Content type: Meeting abstract Published on: 12 March 2000
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Role of the breast cancer susceptibility gene BRCA1 in radio-resistance

Authors: V Sylvain and Y-J Bignon

Citation: Breast Cancer Research 2000 2(Suppl 1):P4.01

Content type: Meeting abstract Published on: 12 March 2000
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BRCA2 interacting proteins

Authors: H Vidarsson, E Mikaelsdottir, JE Eyfjörd, H Ögmundsdóttir, T Rafnar and S Valgeirsdóttir

Citation: Breast Cancer Research 2000 2(Suppl 1):P4.02

Content type: Meeting abstract Published on: 12 March 2000
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Embryonic lethality in the Brca1-1700T mouse model suggests inhibition of p53-dependent pathways

Authors: P Hohenstein, M Kielman, C Breukel, P Krimpenfort, A Berns, M Bennett, R Wiseman, C Cornelisse, G-J van Ommen, P Devilee and R Fodde

Citation: Breast Cancer Research 2000 2(Suppl 1):P4.03

Content type: Meeting abstract Published on: 12 March 2000
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The GSTT1 genotype is associated with p53 mutation status of breast cancer tumours

Authors: K Gudmundsdóttir, L Tryggvadóttir and JE Eyfjörd

Citation: Breast Cancer Research 2000 2(Suppl 1):P4.05

Content type: Meeting abstract Published on: 12 March 2000
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Screening breast cancer patients for Norwegian ATM mutations

Authors: K Laake, P Vu, TI Andersen, B Erikstein, R Kåresen, PE Lønning, E Skovlund and A-L Børresen-Dale

Citation: Breast Cancer Research 2000 2(Suppl 1):P4.08

Content type: Meeting abstract Published on: 12 March 2000
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Analysis of Fhit expression in stages of breast cancer progression

Authors: M Campiglio, G Somenzi, P Aiello, F Wärnberg, L Holmberg, CM Croce and S Menard

Citation: Breast Cancer Research 2000 2(Suppl 1):P4.12

Content type: Meeting abstract Published on: 12 March 2000
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A detailed physical map of a region within human chromosome 16q22.1

Authors: E Frengen, P Rocca-Serra, S Shaposhnikov, L Taine, J Thorsen, C Bépoldin, M Longy, H Prydz and F Dorion-Bonnet

Citation: Breast Cancer Research 2000 2(Suppl 1):P4.15

Content type: Meeting abstract Published on: 12 March 2000
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p16^INK4A as a predictive factor in patients with locally advanced breast cancer treated with neoadjuvant doxorubicin monotherapy

Authors: S Geisler, B Smith-Sørensen, D Betticher, IK Bukholm, LA Akslen, A Kappeler, M Gugger, PE Lønning and A-L Børresen-Dale

Citation: Breast Cancer Research 2000 2(Suppl 1):P5.01

Content type: Meeting abstract Published on: 12 March 2000
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Negative regulation of p53 expression is an essential, rate-limiting function of Jun in the control of cell cycle progression

Authors: M Schreiber, F Piu, A Kolbus, A Szabowski, U Möhle-Steinlein, J Tian, M Karin, P Angel and EF Wagner

Citation: Breast Cancer Research 2000 2(Suppl 1):P5.04

Content type: Meeting abstract Published on: 12 March 2000
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Setting up an efficient and reliable screening method for novel c-Jun N-terminal kinase substrates

Authors: T Kallunki, C Holmberg, M Lerdrup-Hansen, T Herdegen, A Aronheim and M Jäättelä

Citation: Breast Cancer Research 2000 2(Suppl 1):P5.05

Content type: Meeting abstract Published on: 12 March 2000
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Angiogenesis in breast cancer: establishing a link between angiogenesis and hormone regulation

Authors: R Soares, C Costa, F Gärtner and F Schmitt

Citation: Breast Cancer Research 2000 2(Suppl 1):P6.01

Content type: Meeting abstract Published on: 12 March 2000
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AKT-1 and BCL-2 co-expression in breast cancer patients correlates with better survival

Authors: G Pérez-Tenorio and O Stål

Citation: Breast Cancer Research 2000 2(Suppl 1):P7.02

Content type: Meeting abstract Published on: 12 March 2000
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Does a polymorphism in the CYP17 gene predict mammographic density?

Authors: G Ursin, SA Ingles, H Spencer Feigelson, GA Coetzee, L Bernstein, MC Pike and A Buley

Citation: Breast Cancer Research 2000 2(Suppl 1):P7.03

Content type: Meeting abstract Published on: 12 March 2000
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Cytokeratin and mammaglobin as tumor markers in patients with high risk breast cancer

Authors: PF Ferrucci, C Rabascio, C Corsini, F Tealdo, M Paolucci, F Bertolini, H El Taani and G Martinelli

Citation: Breast Cancer Research 2000 2(Suppl 1):P7.05

Content type: Meeting abstract Published on: 12 March 2000
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Promising method for DNA extraction from paraffin embedded archive material

Authors: A Bregård, P Vu, G Geitvik and A-L Børresen-Dale

Citation: Breast Cancer Research 2000 2(Suppl 1):P8.01

Content type: Meeting abstract Published on: 12 March 2000
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REAL Real-Time!

Authors: F Boeckman, L Tan and K Hamby

Citation: Breast Cancer Research 2000 2(Suppl 1):P8.02

Content type: Meeting abstract Published on: 12 March 2000
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Exact quantification of gene amplification in archival tissue sections by laser-assisted microdissection and real-time PCR

Authors: U Lehmann, S Glöckner, W Kleeberger, R von Wasielewski and H Kreipe

Citation: Breast Cancer Research 2000 2(Suppl 1):P8.03

Content type: Meeting abstract Published on: 12 March 2000
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Screening for BRCA1 gene mutations by capillary electrophoretic REF-SSCP

Authors: P Kringen, HG Eiken, JC Pedersen, S Egedal, K Berg, KM Tveit and TI Andersen

Citation: Breast Cancer Research 2000 2(Suppl 1):P8.04

Content type: Meeting abstract Published on: 12 March 2000
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Hypervariable area in the 5' flanking region of GSTP1, previously reported as a minisatellite repeat

Authors: V Nedelcheva Kristensen, T Kristensen and A-L Børresen-Dale

Citation: Breast Cancer Research 2000 2(Suppl 1):P8.05

Content type: Meeting abstract Published on: 12 March 2000
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Comparative genomic hybridisation analysis of myoepithelial carcinoma of the breast

Authors: C Jones, MP Foschini, R Chaggar, Y-J Lu, D Wells, JM Shipley, V Eusebi and SR Lakhani

Citation: Breast Cancer Research 2000 2(Suppl 1):P8.06

Content type: Meeting abstract Published on: 12 March 2000
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Transcript profiles and genotyping of cancer tissue

Authors: C Malmqvist, M Sievertzon, A Gustafsson, A Holmberg, M Larsson, A Alderborn, M Uhlén and J Lundeberg

Citation: Breast Cancer Research 2000 2(Suppl 1):P8.10

Content type: Meeting abstract Published on: 12 March 2000
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Relation of gene expression-based tumor subclasses to clinical phenotypes

Authors: T Sørlie, CM Perou, PE Lønning, PO Brown, D Botstein and A-L Børresen-Dale

Citation: Breast Cancer Research 2000 2(Suppl 1):P8.11

Content type: Meeting abstract Published on: 12 March 2000
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Molecular characteristics of inherited breast tumors

Authors: Å Borg, IA Hedenfalk, J Vallon-Christersson, N Loman, O Johannsson, H Olsson, DJ Duggan, Y Chen, M Bittner, O-P Kallioniemi and JM Trent

Citation: Breast Cancer Research 2000 2(Suppl 1):S.06

Content type: Oral presentation Published on: 12 March 2000
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Estrogen receptors α and β in the rodent mammary gland

Authors: S Saji, EV Jensen, S Nilsson, T Rylander, M Warner and J-Å Gustafsson

Citation: Breast Cancer Research 2000 2(Suppl 1):S.11

Content type: Oral presentation Published on: 12 March 2000
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The EGF receptor family as targets for breast cancer therapy

Authors: J Baselga

Citation: Breast Cancer Research 2000 2(Suppl 1):S.13

Content type: Oral presentation Published on: 12 March 2000
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Herceptin in clinical use - early 2000

Authors: CL Vogel

Citation: Breast Cancer Research 2000 2(Suppl 1):S.15

Content type: Oral presentation Published on: 12 March 2000
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Role of the ATM gene in radiation sensitivity, relevance to breast cancer treatment

Authors: J Hall, S Angèle, M Vuillaume, J-P Gérard and P Romestaing

Citation: Breast Cancer Research 2000 2(Suppl 1):S.24

Content type: Oral presentation Published on: 12 March 2000
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Tumour-selective transcriptional targeting for breast cancer gene therapy

Authors: HC Hurst

Citation: Breast Cancer Research 2000 2(Suppl 1):S.25

Content type: Oral presentation Published on: 12 March 2000
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G1/S control and its deregulation in cancer

Authors: J Bartek, C Lukas, C Sørensen, E Santoni-Rugiu, J Bartkova and J Lukas

Citation: Breast Cancer Research 2000 2(Suppl 1):S.26

Content type: Oral presentation Published on: 12 March 2000
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Molecular control of apoptosis in the breast

Authors: C Streuli, A Gilmore, A Metcalfe, Y-J Lee, J Oliver and A Valentijn

Citation: Breast Cancer Research 2000 2(Suppl 1):S.27

Content type: Oral presentation Published on: 12 March 2000
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Hypoxia and tumour angiogenesis involved in breast cancer progression and targets for therapy

Authors: AL Harris

Citation: Breast Cancer Research 2000 2(Suppl 1):S.28

Content type: Speaker presentations Published on: 12 March 2000
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Telomerase: a breast cancer chemopreventive and therapeutic target

Authors: JW Shay

Citation: Breast Cancer Research 2000 2(Suppl 1):S.29

Content type: Oral presentation Published on: 12 March 2000
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Blood assays for earlier detection of cancers

Authors: AB Pardee, RJ Guan, HL Ford, MV Fournier, K Martin and R Sager

Citation: Breast Cancer Research 2000 2(Suppl 1):S.30

Content type: Oral presentation Published on: 12 March 2000
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Predictive factors in breast cancer

Authors: J Klijn, E Berns, L Dorssers and J Foekens

Citation: Breast Cancer Research 2000 2(Suppl 1):S.32

Content type: Oral presentation Published on: 12 March 2000
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Clinical trials in breast cancer; do we have the right approaches?

Authors: PE Lønning

Citation: Breast Cancer Research 2000 2(Suppl 1):S.33

Content type: Oral presentation Published on: 12 March 2000
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Tissue microarrays for high-throughput profiling in molecular oncology

Authors: O-P Kallioniemi, J Kononen and G Sauter

Citation: Breast Cancer Research 2000 2(Suppl 1):S.34

Content type: Oral presentation Published on: 12 March 2000
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Second International Symposium on the Molecular Biology of Breast Cancer

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