Volume 2 Supplement 1

Second International Symposium on the Molecular Biology of Breast Cancer

Meeting abstracts

Second International Symposium on the Molecular Biology of Breast Cancer.

Lillehammer, Norway12-16 March 2000

Page 1 of 3

Denaturing high-performance liquid chromatography (DHPLC) as a fast tool to screen a control population for the occurrence of unclassified variants (UV) in the BRCA1 gene

Authors: N Arnold, E Gross, H Peper, K Bandick, W Jonat and M Kiechle

Citation: Breast Cancer Research 2000 2(Suppl 1):P1.01

Content type: Meeting abstract

Published on: 12 March 2000
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A novel BRCA2 gene mutation, 4081 insA, in a Finnish breast/ovarian cancer family associated with favourable clinical course

Authors: J Hartikainen, V Kataja and A Mannermaa

Citation: Breast Cancer Research 2000 2(Suppl 1):P1.03

Content type: Meeting abstract

Published on: 12 March 2000
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Breast cancer in young women: prevalence of LOH at p53, BRCA1 and BRCA2

Authors: SM Johnson, JA Shaw and RA Walker

Citation: Breast Cancer Research 2000 2(Suppl 1):P1.04

Content type: Meeting abstract

Published on: 12 March 2000
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BRCA1mutation analysis in breast and ovarian cancer families from Greece

Authors: I Konstantopoulou, C Croupis, A Ladopoulou, A Pantazidis, E Lianidou, K Venetsanou, E Efstathiou, M Petersen, J Janinis, G Fountzilas, E Chiotellis and D Yannoukakos

Citation: Breast Cancer Research 2000 2(Suppl 1):P1.05

Content type: Meeting abstract

Published on: 12 March 2000
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Germline TP53mutations in Finnish breast cancer patients

Authors: K Rapakko, M Allinen, K Syrjäkoski, P Vahteristo, P Huusko, K Vähäkangas, H Eerola, T Kainu, O-P Kallioniemi, H Nevanlinna and R Winqvist

Citation: Breast Cancer Research 2000 2(Suppl 1):P1.09

Content type: Meeting abstract

Published on: 12 March 2000
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Germline BRCA2 and somatic P53alterations in male breast cancer

Authors: B Csokay, N Udvarhelyi and E Olah

Citation: Breast Cancer Research 2000 2(Suppl 1):P1.12

Content type: Meeting abstract

Published on: 12 March 2000
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Constitutional alterations of 9p23-24 in independent BRCA2 breast cancer families

Authors: M Schwab, L Savelyeva, A Claas, H An and S Brouwers

Citation: Breast Cancer Research 2000 2(Suppl 1):P1.13

Content type: Meeting abstract

Published on: 12 March 2000
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kConFab: a unique Australasian research initiative for familial breast cancer

Authors: J Sambrook

Citation: Breast Cancer Research 2000 2(Suppl 1):P1.14

Content type: Meeting abstract

Published on: 12 March 2000
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Germline mutations of BRCA1-associated RING domain (BARD1) gene in breast and/or ovarian families negative for BRCA1 and 2 alterations

Authors: C Ghimenti, E Sensi, D Iandolo, G Cipollini, S Ricci, PF Conte, G Bevilacqua and MA Caligo

Citation: Breast Cancer Research 2000 2(Suppl 1):P1.15

Content type: Meeting abstract

Published on: 12 March 2000
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Relative expression of progesterone receptors A and B in premalignant and invasive breast lesions

Authors: P Mote and C Clarke

Citation: Breast Cancer Research 2000 2(Suppl 1):P2.01

Content type: Meeting abstract

Published on: 12 March 2000
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Phosphorylation of human progesterone receptors by MAPKs mediates transcriptional synergy between progestins and MEKK1 in human breast cancer cells

Authors: CA Lange, T Shen and KB Horwitz

Citation: Breast Cancer Research 2000 2(Suppl 1):P2.06

Content type: Meeting abstract

Published on: 12 March 2000
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The expression of the EGFR family members in breast carcinomas

Authors: Z Suo and JM Nesland

Citation: Breast Cancer Research 2000 2(Suppl 1):P3.01

Content type: Meeting abstract

Published on: 12 March 2000
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Expression of Akt kinases related to ErbB2 and results of adjuvant therapy of breast cancer

Authors: O Stal, L Akerberg, B Nordenskjold, B Olsson, LE Rutqvist and L Skoog

Citation: Breast Cancer Research 2000 2(Suppl 1):P3.04

Content type: Meeting abstract

Published on: 12 March 2000
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Anti-HER2 mAb plus calicheamicin immunoconjugate linked on liposomal vinorelbine induces ADCC and apoptosis in HER2-positive high grade DCIS

Authors: J Giannos and P Ginopulos

Citation: Breast Cancer Research 2000 2(Suppl 1):P3.05

Content type: Meeting abstract

Published on: 12 March 2000
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Herceptin™ (trastuzumab) in patients who overexpress Her-2 and have failed multiple chemotherapy regimens for advanced breast cancer: a pragmatic study

Authors: G Westman

Citation: Breast Cancer Research 2000 2(Suppl 1):P3.08

Content type: Meeting abstract

Published on: 12 March 2000
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Heterogeneity in the clinical phenotype of TP53 mutations in breast cancer patients

Authors: J Alsner, M Yilmaz, P Guldberg, LL Hansen and J Overgaard

Citation: Breast Cancer Research 2000 2(Suppl 1):P4.04

Content type: Meeting abstract

Published on: 12 March 2000
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Studies of TP53 haplotypes in relation to LOH and TP53 mutations in breast cancer patients

Authors: A Langerød, TI Andersen, I Bukholm and A-L Børresen Dale

Citation: Breast Cancer Research 2000 2(Suppl 1):P4.06

Content type: Meeting abstract

Published on: 12 March 2000
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P53 mutations in breast and ovarian carcinomas from BRCA1 and 2 mutation carriers and noncarriers

Authors: E Sensi, C Ghimenti, G Cipollini, D Iandolo, G Naccarato, P Viacava, G Bevilacqua and MA Caligo

Citation: Breast Cancer Research 2000 2(Suppl 1):P4.07

Content type: Meeting abstract

Published on: 12 March 2000
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Constitutional alterations of the ATM gene in early-onset sporadic breast cancer

Authors: P Maillet, H Bonnefoi and A-P Sappino

Citation: Breast Cancer Research 2000 2(Suppl 1):P4.09

Content type: Meeting abstract

Published on: 12 March 2000
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Modulation of ATM gene expression in a murine mammary epithelial cell line

Authors: GV Vutskits, P Salmon, JV Soriano, C Cudre-Mauroux, D Trono, R Montesano and A-P Sappino

Citation: Breast Cancer Research 2000 2(Suppl 1):P4.10

Content type: Meeting abstract

Published on: 12 March 2000
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Loss of heterozygosity on chromosome arm 16q in breast cancer: clinical, molecular and statistical approaches

Authors: A-M Cleton-Jansen, HM van Beerendonk, NT ter Haar, PHC Eilers, HC van Houwelingen, BA Bonsing, VTHBM Smit, G-JB van Ommen and CJ Cornelisse

Citation: Breast Cancer Research 2000 2(Suppl 1):P4.11

Content type: Meeting abstract

Published on: 12 March 2000
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Analysis of chromosome alterations and the E-cadherin and FHIT genes in lobular breast cancer

Authors: S Ingvarsson, C Huiping, JG Jonasson and BA Agnarsson

Citation: Breast Cancer Research 2000 2(Suppl 1):P4.13

Content type: Meeting abstract

Published on: 12 March 2000
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Excluding TTC4 as a target for loss on chromosome 1p31 in human breast cancer

Authors: Y Hey, W Brintnell, L James and J Varley

Citation: Breast Cancer Research 2000 2(Suppl 1):P4.14

Content type: Meeting abstract

Published on: 12 March 2000
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Expression of variant forms of the MUC1 gene correlates with the invasiveness of breast cancer cells

Authors: R Zeillinger, B Schmid, D Tong, B Fasching, I Schiebl, M Stimpfl, A Obermair and S Leodolter

Citation: Breast Cancer Research 2000 2(Suppl 1):P4.16

Content type: Meeting abstract

Published on: 12 March 2000
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Low frequency of p16 ^INK4a promoter methylation in mammary carcinomas as revealed by positive display of methylated sites

Authors: R Lilischkis, H Kneitz and H Kreipe

Citation: Breast Cancer Research 2000 2(Suppl 1):P5.02

Content type: Meeting abstract

Published on: 12 March 2000
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Estrogen-dependent c-jun upregulation may control cyclin D1 expression

Authors: MD Planas-Silva, J Liu Donaher and RA Weinberg

Citation: Breast Cancer Research 2000 2(Suppl 1):P5.03

Content type: Meeting abstract

Published on: 12 March 2000
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Development of a high throughput, molecular diagnostic assay for predicting telomerase activity in breast cancer cell lines and tissues

Authors: L Elmore, A Akalin, L Gollahon, G Clarke, M Grimes, RT Burks, A Ferreira-Gonzalez, C Garrett and S Holt

Citation: Breast Cancer Research 2000 2(Suppl 1):P6.02

Content type: Meeting abstract

Published on: 12 March 2000
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Mammary epithelial cells immortalized by over-expression of the catalytic subunit of human telomerase may represent a model for mammary epithelial differentiation

Authors: J DiRenzo, R Rivera-Gonzalez and M Brown

Citation: Breast Cancer Research 2000 2(Suppl 1):P6.03

Content type: Meeting abstract

Published on: 12 March 2000
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Molecular analyses of human breast cancer metastasis: genetic markers of progression

Authors: K Driouch and R Lidereau

Citation: Breast Cancer Research 2000 2(Suppl 1):P7.01

Content type: Meeting abstract

Published on: 12 March 2000
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Ribozymes targeting the tumor suppressor BRCA1 lead to increased chemosensitivity to cisplatin and etoposide and chemoresistance to microtubule-interfering agents in HBL100 breast cancer cell line

Authors: S Lafarge, M Ferrara and YJ Bignon

Citation: Breast Cancer Research 2000 2(Suppl 1):P7.04

Content type: Meeting abstract

Published on: 12 March 2000
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Genetic alterations in ductal carcinoma in situ and invasive carcinoma of the breast

Authors: E Robanus-Maandag, C Bosch, C Vos, H Peterse and M van de Vijver

Citation: Breast Cancer Research 2000 2(Suppl 1):P8.07

Content type: Meeting abstract

Published on: 12 March 2000
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Identification of two novel breast cancer associated genes by the differential display method

Authors: N Maass, K Nagasaki, VR Jacobs and W Jonat

Citation: Breast Cancer Research 2000 2(Suppl 1):P8.08

Content type: Meeting abstract

Published on: 12 March 2000
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Expression profiling of BRCA1 associated breast tumors

Authors: EMJJ Berns, IL van Staveren, L Verhoog, JA Foekens and JGM Klijn

Citation: Breast Cancer Research 2000 2(Suppl 1):P8.09

Content type: Meeting abstract

Published on: 12 March 2000
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The importance of breast cancer research from a patient's view: the voices and visions of advocates

Authors: S Leigh

Citation: Breast Cancer Research 2000 2(Suppl 1):S.01

Content type: Oral presentation

Published on: 12 March 2000
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Genetic testing for BRCA1 and BRCA2 mutations - ready for implementation?

Authors: BL Weber

Citation: Breast Cancer Research 2000 2(Suppl 1):S.04

Content type: Oral presentation

Published on: 12 March 2000
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The pathology of inherited breast tumours

Authors: M Stratton

Citation: Breast Cancer Research 2000 2(Suppl 1):S.05

Content type: Oral presentation

Published on: 12 March 2000
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Other cancers in BRCA1 and BRCA2 mutation carriers: implications for counselling and follow up

Authors: B Ponder

Citation: Breast Cancer Research 2000 2(Suppl 1):S.07

Content type: Oral presentation

Published on: 12 March 2000
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The role of coactivators in oestrogen action

Authors: M Brown and JF de Mora

Citation: Breast Cancer Research 2000 2(Suppl 1):S.08

Content type: Oral presentation

Published on: 12 March 2000
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Growth regulation and steroid hormone resistance in breast cancer

Authors: KB Horwitz

Citation: Breast Cancer Research 2000 2(Suppl 1):S.09

Content type: Oral presentation

Published on: 12 March 2000
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Clinical translation of progress in molecular endocrinology

Authors: M Dowsett

Citation: Breast Cancer Research 2000 2(Suppl 1):S.12

Content type: Oral presentation

Published on: 12 March 2000
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Use of the anti HER-2/neu antibody Herceptin in the treatment of human breast cancer: biological rationale and clinical results

Authors: DJ Slamon

Citation: Breast Cancer Research 2000 2(Suppl 1):S.14

Content type: Oral presentation

Published on: 12 March 2000
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Characterisation of micrometastatic tumor cells

Authors: K Pantel

Citation: Breast Cancer Research 2000 2(Suppl 1):S.16

Content type: Oral presentation

Published on: 12 March 2000
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Animal models of human tumor suppressor genes

Authors: TW Mak

Citation: Breast Cancer Research 2000 2(Suppl 1):S.17

Content type: Oral presentation

Published on: 12 March 2000
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Drug discovery in the p53 pathway

Authors: DP Lane, C Midgley, A Sparks, C Blattner, C Binden and S Laine

Citation: Breast Cancer Research 2000 2(Suppl 1):S.18

Content type: Oral presentation

Published on: 12 March 2000
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Carcinoma-associated fibroblasts stimulate tumor progression of initiated human epithelium

Authors: AF Olumi, GD Grossfeld, SW Hayward, PR Carroll, GR Cunha, P Hein and TD Tlsty

Citation: Breast Cancer Research 2000 2(Suppl 1):S.19

Content type: Oral presentation

Published on: 12 March 2000
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p53-mediated apoptosis and genomic instability syndromes

Authors: EA Spillare, XW Wang, SP Linke, A Robles and CC Harris

Citation: Breast Cancer Research 2000 2(Suppl 1):S.20

Content type: Oral presentation

Published on: 12 March 2000
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Lessons from TP53mutations in breast cancers: from carcinogen fingerprints to clinical correlates

Authors: P Hainaut and M Olivier

Citation: Breast Cancer Research 2000 2(Suppl 1):S.21

Content type: Oral presentation

Published on: 12 March 2000
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p53 action in apoptosis and senescence

Authors: SW Lowe, CA Schmitt, G Ferbeyre, AW Lin, E de Stanchina and M Soengas

Citation: Breast Cancer Research 2000 2(Suppl 1):S.22

Content type: Oral presentation

Published on: 12 March 2000
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Cancer susceptibility in ATM heterozygotes: do two distinct carrier populations exist?

Authors: RA Gatti and P Concannon

Citation: Breast Cancer Research 2000 2(Suppl 1):S.23

Content type: Oral presentation

Published on: 12 March 2000
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Clinical and pathological characteristics in patients with BRCA1/2-mutation associated with breast cancer (BC) with a long clinical follow-up

Authors: O Díez, C Pericay, M Domènech, J Brunet, J Cortés, J Balmaña, A Gómez, JJ López, MC Alonso and M Baiget

Citation: Breast Cancer Research 2000 2(Suppl 1):P1.02

Content type: Meeting abstract

Published on: 12 March 2000
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Second International Symposium on the Molecular Biology of Breast Cancer

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