Open Access

Erratum to: Loss of plakoglobin promotes decreased cell-cell contact, increased invasion, and breast cancer cell dissemination in vivo

  • Ingunn Holen1,
  • Jacob Whitworth1,
  • Faith Nutter1,
  • Alyson Evans1,
  • Hannah K. Brown1,
  • Diane V. Lefley1,
  • Ivana Barbaric2,
  • Mark Jones2 and
  • Penelope D. Ottewell1, 3Email author
Breast Cancer Research201719:37

Received: 6 March 2017

Accepted: 6 March 2017

Published: 28 March 2017

The original article was published in Breast Cancer Research 2012 14:3000


After the publication of this study [1] an error was detected in Fig. 2e. The same image was accidently used for beta-catenin staining of MCF7 2A-1 and T47D 2A-4. This error does not affect the findings or conclusions of the article. The corrected figure is shown below and we apologise for this mistake.
Fig. 2

Shows relative expression of plakoglobin and e-cadherin compared with GAPDH ± SEM before and after siRNA knockdown with (a) scramble sequence or miRNA cassette 2 in MCF7 cells, (b) scramble sequence or miRNA cassette 3 in MCF7 cells, (c) scramble sequence or miRNA cassette 2 in T47D cells. d Are Western blots showing gamma catenin and E-cadherin expression following transfection with scramble sequence or miRNA cassettes 2 and 3. e Shows immunohistochemical staining for γ-catenin, e-cadherin and beta-catenin (green). In the control cells γ-catenin, e-cadherin and β-catenin are expressed on the cell surface clearly demarcating the cell-cell junctions. In the knock down lines, γ-catenin staining is reduced and e-cadherin and β-catenin is detected in the nucleus and the cytoplasm and β-catenin



Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (, which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver ( applies to the data made available in this article, unless otherwise stated.

Authors’ Affiliations

Academic Unit of Clinical Oncology
Centre for Stem Cell Research, Biomedical Sciences, Western Bank, University of Sheffield
Academic Unit of Clinical Oncology, CR-UK/YCR Sheffield Cancer Research Centre, University of Sheffield


  1. Holen I, Whitworth J, Nutter F, Evans A, Brown HK, Lefley DV, Barbaric I, Jones M, Ottewell PD. Loss of plakoglobin promotes decreased cell-cell contact, increased invasion and breast cancer cell dissemination in vivo. Breast Cancer Res. 2012;14(3):R86.View ArticlePubMedPubMed CentralGoogle Scholar


© The Author(s). 2017