Figure 5From: Insulin-like growth factor-I inhibition with pasireotide decreases cell proliferation and increases apoptosis in pre-malignant lesions of the breast: a phase 1 proof of principle trialEffect of treatment with pasireotide on phospho insulin-like growth factor -1 receptor (IGF-1R). Effect of pasireotide on mean intensity of phospho IGF-1R by immunofluorescence in four patients with atypical hyperplasia before and after treatment with pasireotide (A) and five controls (B). Representative sections from one of the patients before (C) and after treatment (D). DAPI: 4',6-diamidino-2-phenylindole; n.s., not significant.Back to article page