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Table 3 Daily number of hot flushes and menopausal symptom score at baseline and after 12 months, and change from baseline to 12 months by treatment group

From: Red clover-derived isoflavones and mammographic breast density: a double-blind, randomized, placebo-controlled trial [ISRCTN42940165]

  Isoflavone (n = 45, n = 70)a Placebo (n = 54, n= 83)a  
  Baseline 12 months Change Baseline 12 months Change P for changeb
Mean daily number of hot flushes 2.1 ± 2.7 1.2 ± 2.3 -0.8 ± 2.1 2.5 ± 3.0 1.5 ± 2.0 -1.0 ± 1.8 0.41
Menopausal symptom score 4.3 ± 4.3 3.4 ± 4.1 -0.9 ± 4.1 4.3 ± 4.3 3.5 ± 3.8 -0.8 ± 2.8 0.88
  1. Analyses based on women who reported hot flushes or menopausal symptoms in one or both diaries. Values are expressed as means ± standard deviation. a Shown in parentueses are the number of women with hot flushes and number of women with any menopausal symptoms, respectively. b P value for difference between treatment groups for change.