Nusse R, Varmus HE: Many tumors induced by the mouse mammary tumor virus contain a provirus integrated in the same region of the host genome. Cell. 1982, 31: 99-109.
Article
CAS
PubMed
Google Scholar
Bittner JJ: The milk influence of breast tumors in mice. Science. 1942, 95: 463-
Article
Google Scholar
Nusse R, Varmus HE: Wnt genes. Cell. 1992, 69: 1073-1087.
Article
CAS
PubMed
Google Scholar
Tsukamoto AS, Grosschedl R, Guzman RC, Parslow T, Varmus HE: Expression of the int-1 gene in transgenic mice is associated with mammary gland hyperplasia and adenocarcinomas in male and female mice. Cell. 1988, 55: 619-625.
Article
CAS
PubMed
Google Scholar
De Ome KB, Faulkin LJ, Bern HA: Development of mammary tumors from hyperplastic alveolar nodules transplanted into gland-free mammary fat pads of female C3H mice. Cancer Res. 1959, 19: 515-520.
CAS
Google Scholar
Nusse R: Insertional mutagenesis in mouse mammary tumori-genesis. Curr Topics Microbiol Immunol. 1991, 171: 43-66.
CAS
Google Scholar
Van de Vijver MJ, Nusse R: The molecular biology of breast cancer. Biochim Biophys Acta Rev Cancer. 1991, 1072: 33-50. 10.1016/0304-419X(91)90005-6.
Article
CAS
Google Scholar
Cadigan KM, Nusse R: Wnt signaling: a common theme in animal development. Genes Dev. 1997, 11: 3286-3305.
Article
CAS
PubMed
Google Scholar
Herzlinger D, Qiao J, Cohen D, Ramakrishna NR, Brown AMC: Induction of kidney epithelial morphogenesis by cells expressing Wnt-1. Dev Biol. 1994, 166: 815-819. 10.1006/dbio.1994.1360.
Article
CAS
PubMed
Google Scholar
Kispert A, Vainio S, McMahon AP: Wnt-4 is a mesenchymal signal for epithelial transformation of metanephric mesenchyme in the developing kidney. Development. 1998, 125: 4225-4234.
CAS
PubMed
Google Scholar
Shimizu H, Julius MA, Zheng Z, Giarre M, Brown AMC, Kitajewski J: Mammary cell transformation by Wnt family proteins correlates with regulation of beta-catenin. Cell Growth Differ. 1997, 8: 1349-1358.
CAS
PubMed
Google Scholar
Bergstein I, Brown AMC: WNT genes and breast cancer. In Breast Cancer: Molecular Genetics, Pathogenesis and Therapeutics. Edited by Bowcock AM. Totowa, NJ: Humana Press Inc.;. 1999, 181-198.
Google Scholar
Lane TF, Leder P: Wnt-10b directs hypermorphic development and transformation in mammary glands of male and female mice. Oncogene. 1997, 15: 2133-2144. 10.1038/sj/onc/1201593.
Article
CAS
PubMed
Google Scholar
Gavin BJ, McMahon JA, McMahon AP: Expression of multiple novel Wnt-1/int-1-related genes during fetal and adult mouse development. Genes Dev. 1990, 4: 2319-2332.
Article
CAS
PubMed
Google Scholar
Weber-Hall SJ, Phippard DJ, Niemeyer CC, Dale TC: Developmental and hormonal regulation of Wnt gene expression in the mouse mammary gland. Differentiation. 1994, 57: 205-214. 10.1007/s002580050056.
Article
CAS
PubMed
Google Scholar
Brisken C, Heineman A, Chavarria T, Elenbaas B, Tan J, Dey SK, McMahon JA, McMahon AP, Weinberg RA: Essential function of Wnt-4 in mammary gland development downstream of prog-esterone signaling. Genes Dev. 2000, 14: 650-654.
CAS
PubMed
PubMed Central
Google Scholar
Huguet EL, McMahon JA, McMahon AP, Bicknell R, Harris AL: Differential expression of human Wnt genes 2, 3, 4, and 7B in human breast cell lines and normal and diseased breast tissue. Cancer Res. 1994, 54: 2615-2621.
CAS
PubMed
Google Scholar
Dale TC, Weber-Hall SJ, Smith K, Huguet EL, Jayatliake H, Gusterson BA, Shuttleworth G, O'Hare M, Harris AL: Compartment switching of WNT-2 expression in human breast tumors. Cell Regulat. 1996, 56: 4320-4323.
CAS
Google Scholar
Lejeune S, Huguet EL, Hamby A, Poulsom R, Harris AL: Wnt5a cloning, expression, and up-regulation in human primary breast cancers. Clin Cancer Res. 1995, 1: 215-222.
CAS
PubMed
Google Scholar
Bui TD, Rankin J, Smith K, Huguet EL, Ruben S, Strachan T, Harris AL, Lindsay S: A novel human Wnt gene, WNT10B, maps to 12q13 and is expressed in human breast carcinomas. Oncogene. 1997, 14: 1249-1253. 10.1038/sj/onc/1200936.
Article
CAS
PubMed
Google Scholar
Polakis P: Wnt signaling and cancer. Genes Dev. 2000, 14: 1837-1851.
CAS
PubMed
Google Scholar
Mao J, Wang J, Liu B, Pan W, Farr GH, Flynn C, Yuan H, Takada S, Kimelman D, Li L, Wu D: Low-density lipoprotein receptor-related protein-5 binds to Axin and regulates the canonical Wnt signaling pathway. Mol Cell. 2001, 7: 801-809. 10.1016/S1097-2765(01)00224-6.
Article
CAS
PubMed
Google Scholar
Mao B, Wu W, Li Y, Hoppe D, Stannek P, Glinka A, Niehrs C: LDL-receptor-related protein 6 is a receptor for Dickkopf proteins. Nature. 2001, 411: 321-325. 10.1016/S0370-2693(97)00972-6.
Article
CAS
PubMed
Google Scholar
Satoh S, Daigo Y, Furukawa Y, Kato T, Miwa N, Nishiwaki T, Kawasoe T, Ishiguro H, Fujita M, Tokino T, Sasaki Y, Imaoka S, Murata M, Shimano T, Yamaoka Y, Nakamura Y: AXIN1 mutations in hepatocellular carcinomas, and growth suppression in cancer cells by virus-mediated transfer of AXIN1. Nat Genet. 2000, 24: 245-250. 10.1038/73448.
Article
CAS
PubMed
Google Scholar
Moser AR, Hegge LF, Cardiff RD: Genetic background affects susceptibility to mammary hyperplasias and carcinomas in Apc(min)/+ mice. Cancer Res. 2001, 61: 3480-3485.
CAS
PubMed
Google Scholar
Imbert A, Eelkema R, Jordan S, Feiner H, Cowin P: ΔN89β-catenin induces precocious development, differentiation, and neoplasia in mammary gland. J Cell Biol. 2001, 153: 555-568. 10.1083/jcb.153.3.555.
Article
CAS
PubMed
PubMed Central
Google Scholar
Candidus S, Bischoff P, Becker KF, Hofler H: No evidence for mutations in the alpha- and beta-catenin genes in human gastric and breast carcinomas. Cancer Res. 1996, 56: 49-52.
CAS
PubMed
Google Scholar
Schlosshauer PW, Brown SA, Eisinger K, Yan Q, Guglielminetti ER, Parsons R, Ellenson LH, Kitajewski J: APC truncation and increased beta-catenin levels in a human breast cancer cell line. Carcinogenesis. 2000, 21: 1453-1456. 10.1093/carcin/21.7.1453.
Article
CAS
PubMed
Google Scholar
Jonsson M, Borg A, Nilbert M, Andersson T: Involvement of ade-nomatous polyposis coli (APC)/beta-catenin signalling in human breast cancer. Eur J Cancer. 2000, 36: 242-248. 10.1016/S0959-8049(99)00276-2.
Article
CAS
PubMed
Google Scholar
Furuuchi K, Tada M, Yamada H, Kataoka A, Furuuchi N, Hamada J, Takahashi M, Todo S, Moriuchi T: Somatic mutations of the APC gene in primary breast cancers. Am J Pathol. 2000, 156: 1997-2005.
Article
CAS
PubMed
PubMed Central
Google Scholar
Webster MT, Rozycka M, Sara E, Davis E, Smalley M, Young N, Dale TC, Wooster R: Sequence variants of the axin gene in breast, colon, and other cancers: an analysis of mutations that interfere with GSK3 binding. Genes Chromosomes Cancer. 2000, 28: 443-453. 10.1002/1098-2264(200008)28:4<443::AID-GCC10>3.3.CO;2-4.
Article
CAS
PubMed
Google Scholar
Lin SY, Xia W, Wang JC, Kwong KY, Spohn B, Wen Y, Pestell RG, Hung MC: Beta-catenin, a novel prognostic marker for breast cancer: its roles in cyclin D1 expression and cancer progression. Proc Natl Acad Sci USA. 2000, 97: 4262-4266. 10.1073/pnas.060025397.
Article
CAS
PubMed
PubMed Central
Google Scholar
Tanaka S, Akiyoshi T, Mori M, Wands JR, Sugimachi K: A novel frizzled gene identified in human esophageal carcinoma mediates APC/beta-catenin signals. Proc Natl Acad Sci USA. 1998, 85: 10164-10169. 10.1073/pnas.95.17.10164.
Article
Google Scholar
Martinez Arias A, Brown AMC, Brennan K: Wnt signalling: pathway or network?. Curr Opin Genet Dev. 1999, 9: 447-454. 10.1016/S0959-437X(99)80068-9.
Article
Google Scholar
Rijsewijk F, Schuerman M, Wagenaar E, Parren P, Weigel D, Nusse R: The Drosophila homolog of the mouse mammary oncogene int-1 is identical to the segment polarity gene wingless. Cell. 1987, 50: 649-657.
Article
CAS
PubMed
Google Scholar
Riggleman B, Schedl P, Wieschaus E: Spatial expression of the Drosophila segment polarity gene armadillo is posttranscrip-tionally regulated by wingless. Cell. 1990, 63: 549-560.
Article
CAS
PubMed
Google Scholar
Funayama N, Fagotto F, McCrea P, Gumbiner B: Embryonic axis induction by the armadillo repeat domain of beta-catenin: evidence for intercellular signaling. J Cell Biol. 1995, 128: 959-968.
Article
CAS
PubMed
Google Scholar
Kinzler KW, Vogelstein B: Lessons from hereditary colorectal cancer. Cell. 1996, 87: 159-170.
Article
CAS
PubMed
Google Scholar
Munemitsu S, Albert I, Souza B, Rubinfeld B, Polakis P: Regulation of intracellular beta-catenin levels by adenomatous poly-posis coli (APC) tumor-suppressor protein. Proc Natl Acad Sci USA. 1995, 92: 3046-3050.
Article
CAS
PubMed
PubMed Central
Google Scholar