Palacios J, Honrado E, Osorio A, Cazorla A, Sarrio D, Barroso A, Rodriguez S, Cigudosa JC, Diez O, Alonso C, Sanchez L, Rivas C, Benitez J: Immunohistochemical characteristics defined by tissue microarray of hereditary breast cancer not attributable to BRCA1 or BRCA2 mutations: differences from breast carcinomas arising in BRCA1 and BRCA2 mutation carriers. Clin Cancer Res. 2003, 9: 3606-3614.
CAS
PubMed
Google Scholar
Lakhani SR, Gusterson BA, Jacquemier J, Sloane JP, Anderson TJ, van de Vijver MJ, Venter D, Freeman A, Antoniou A, McGuffog L, Smyth E, Steel CM, Haites N, Scott RJ, Goldgar D, Neuhausen S, Daly PA, Ormiston W, McManus R, Scherneck S, Ponder BA, Futreal PA, Peto J, Stoppa-Lyonnet D, Bignon YJ, Stratton MR: The pathology of familial breast cancer: histological features of cancers in families not attributable to mutations in BRCA1 or BRCA2. Clin Cancer Res. 2000, 6: 782-789.
CAS
PubMed
Google Scholar
Palacios J, Honrado E, Osorio A, Cazorla A, Sarrio D, Barroso A, Rodriguez S, Cigudosa JC, Diez O, Alonso C, Lerma E, Dopazo J, Rivas C, Benitez J: Phenotypic characterization of BRCA1 and BRCA2 tumors based in a tissue microarray study with 37 immunohistochemical markers. Breast Cancer Res Treat. 2005, 90: 5-14. 10.1007/s10549-004-1536-0.
Article
CAS
PubMed
Google Scholar
Foulkes WD, Stefansson IM, Chappuis PO, Begin LR, Goffin JR, Wong N, Trudel M, Akslen LA: Germline BRCA1 mutations and a basal epithelial phenotype in breast cancer. J Natl Cancer Inst. 2003, 95: 1482-1485. 10.1093/jnci/djg050.
Article
CAS
PubMed
Google Scholar
Lakhani SR, Reis-Filho JS, Fulford L, Penault-Llorca F, van der Vijver M, Parry S, Bishop T, Benitez J, Rivas C, Bignon YJ, Chang-Claude J, Hamann U, Cornelisse CJ, Devilee P, Beckmann MW, Nestle-Kramling C, Daly PA, Haites N, Varley J, Lalloo S, Radice P, Scherneck S, Sobol H, Jacquemier J, Wagner T, Peto J, Stratton MR, McGuffog L, Easton DF: Prediction of BRCA1 status in patients with breast cancer using estrogen receptor and basal phenotype. Clin Cancer Res. 2005, 11: 5175-5180. 10.1158/1078-0432.CCR-04-2424.
Article
CAS
PubMed
Google Scholar
Armes JE, Egan AJ, Southey MC, Dite GS, McCredie MR, Giles GG, Hopper JL, Venter DJ: The histologic phenotypes of breast carcinoma occurring before age 40 years in women with and without BRCA1 or BRCA2 germline mutations: a population-based study. Cancer. 1998, 83: 2335-2345. 10.1002/(SICI)1097-0142(19981201)83:11<2335::AID-CNCR13>3.0.CO;2-N.
Article
CAS
PubMed
Google Scholar
Nasmyth K, Haering CH: Cohesin: its roles and mechanisms. Annu Rev Genet. 2009, 43: 525-558. 10.1146/annurev-genet-102108-134233.
Article
CAS
PubMed
Google Scholar
Peters JM, Tedeschi A, Schmitz J: The cohesin complex and its roles in chromosome biology. Genes Dev. 2008, 22: 3089-3114. 10.1101/gad.1724308.
Article
CAS
PubMed
Google Scholar
Schmidt D, Schwalie PC, Ross-Innes CS, Hurtado A, Brown GD, Carroll JS, Flicek P, Odom DT: A CTCF-independent role for cohesin in tissue-specific transcription. Genome Res. 2010, 20: 578-588. 10.1101/gr.100479.109.
Article
CAS
PubMed
PubMed Central
Google Scholar
Rollins RA, Korom M, Aulner N, Martens A, Dorsett D: Drosophila nipped-B protein supports sister chromatid cohesion and opposes the stromalin/Scc3 cohesion factor to facilitate long-range activation of the cut gene. Mol Cell Biol. 2004, 24: 3100-3111. 10.1128/MCB.24.8.3100-3111.2004.
Article
CAS
PubMed
PubMed Central
Google Scholar
Rhodes DR, Yu J, Shanker K, Deshpande N, Varambally R, Ghosh D, Barrette T, Pandey A, Chinnaiyan AM: Large-scale meta-analysis of cancer microarray data identifies common transcriptional profiles of neoplastic transformation and progression. Proc Natl Acad Sci USA. 2004, 101: 9309-9314. 10.1073/pnas.0401994101.
Article
CAS
PubMed
PubMed Central
Google Scholar
Oishi Y, Nagasaki K, Miyata S, Matsuura M, Nishimura S, Akiyama F, Iwai T, Miki Y: Functional pathway characterized by gene expression analysis of supraclavicular lymph node metastasis-positive breast cancer. J Hum Genet. 2007, 52: 271-279. 10.1007/s10038-007-0111-z.
Article
CAS
PubMed
Google Scholar
Xu X, Yan M, Natrajan R, Yan Y, Swagemakers S, Tomaszewski JM, Verschoor S, Millar EKA, van der Spek P, Reis-Filho J, Ramsay RG, O'Toole SA, McNeil CM, Sutherland RL, MacKay MJ, Fox SB: Enhanced Rad21 cohesin expression confers poor prognosis and resistance to chemotherapy in high grade luminal, basal and HER2 breast cancers. Breast Cancer Res. 2011, 32: 13 R9-
Google Scholar
Atienza JM, Roth RB, Rosette C, Smylie KJ, Kammerer S, Rehbock J, Ekblom J, Denissenko MF: Suppression of RAD21 gene expression decreases cell growth and enhances cytotoxicity of etoposide and bleomycin in human breast cancer cells. Mol Cancer Ther. 2005, 4: 361-368.
CAS
PubMed
Google Scholar
Yan M, Rayoo M, Takano EA, Fox SB: Nuclear and cytoplasmic expressions of ERbeta1 and ERbeta2 are predictive of response to therapy and alters prognosis in familial breast cancers. Breast Cancer Res Treat. 2011, 126: 395-405. 10.1007/s10549-010-0941-9.
Article
CAS
PubMed
Google Scholar
McShane LM, Altman DG, Sauerbrei W, Taube SE, Gion M, Clark GM: Reporting recommendations for tumor marker prognostic studies. J Clin Oncol. 2005, 23: 9067-9072. 10.1200/JCO.2004.01.0454.
Article
PubMed
Google Scholar
Kathleen Cuningham Foundation Consortium for Research into Familial Breast Cancer, Enrolment of Families and Data Collection. [http://www.kconfab.org/Index.shtml]
Nielsen TO, Hsu FD, Jensen K, Cheang M, Karaca G, Hu Z, Hernandez-Boussard T, Livasy C, Cowan D, Dressler L, Akslen LA, Ragaz J, Gown AM, Gilks CB, van de Rijn M, Perou CM: Immunohistochemical and clinical characterization of the basal-like subtype of invasive breast carcinoma. Clin Cancer Res. 2004, 10: 5367-5374. 10.1158/1078-0432.CCR-04-0220.
Article
CAS
PubMed
Google Scholar
Leake R, Barnes D, Pinder S, Ellis I, Anderson L, Anderson T, Adamson R, Rhodes T, Miller K, Walker R: Immunohistochemical detection of steroid receptors in breast cancer: a working protocol; UK Receptor Group, UK NEQAS, The Scottish Breast Cancer Pathology Group, and The Receptor and Biomarker Study Group of the EORTC. J Clin Pathol. 2000, 53: 634-635. 10.1136/jcp.53.8.634.
Article
CAS
PubMed
PubMed Central
Google Scholar
Waddell N, Arnold J, Cocciardi S, da Silva L, Marsh A, Riley J, Johnstone CN, Orloff M, Assie G, Eng C, Reid L, Keith P, Yan M, Fox S, Devilee P, Godwin AK, Hogervorst FB, Couch F, Grimmond S, Flanagan JM, Khanna K, Simpson PT, Lakhani SR, Chenevix-Trench G: Subtypes of familial breast tumours revealed by expression and copy number profiling. Breast Cancer Res Treat. 2010, 123: 661-677. 10.1007/s10549-009-0653-1.
Article
PubMed
Google Scholar
Lingjaerde OC, Baumbusch LO, Liestol K, Glad IK, Borresen-Dale AL: CGH-Explorer: a program for analysis of array-CGH data. Bioinformatics. 2005, 21: 821-822. 10.1093/bioinformatics/bti113.
Article
CAS
PubMed
Google Scholar
Assie G, LaFramboise T, Platzer P, Bertherat J, Stratakis CA, Eng C: SNP arrays in heterogeneous tissue: highly accurate collection of both germline and somatic genetic information from unpaired single tumor samples. Am J Hum Genet. 2008, 82: 903-915. 10.1016/j.ajhg.2008.01.012.
Article
CAS
PubMed
PubMed Central
Google Scholar
Buffa FM, Camps C, Winchester L, Snell CE, Gee HE, Sheldon H, Taylor M, Harris AL, Ragoussis J: microRNA associated progression pathways and potential therapeutic targets identified by integrated mRNA and microRNA expression profiling in breast cancer. Cancer Res. 2011, 71: 5635-5645. 10.1158/0008-5472.CAN-11-0489.
Article
CAS
PubMed
Google Scholar
Chen J, Lozach J, Garcia EW, Barnes B, Luo S, Mikoulitch I, Zhou L, Schroth G, Fan JB: Highly sensitive and specific microRNA expression profiling using BeadArray technology. Nucleic Acids Res. 2008, 36: e87-10.1093/nar/gkn387.
Article
PubMed
PubMed Central
Google Scholar
Pradervand S, Weber J, Thomas J, Bueno M, Wirapati P, Lefort K, Dotto GP, Harshman K: Impact of normalization on miRNA microarray expression profiling. RNA (New York). 2009, 15: 493-501. 10.1261/rna.1295509.
Article
CAS
Google Scholar
Pradervand S, Weber J, Lemoine F, Consales F, Paillusson A, Dupasquier M, Thomas J, Richter H, Kaessmann H, Beaudoing E, Hagenbuchle O, Harshman K: Concordance among digital gene expression, microarrays, and qPCR when measuring differential expression of microRNAs. BioTechniques. 2010, 48: 219-222. 10.2144/000113367.
Article
CAS
PubMed
Google Scholar
Griffiths-Jones S, Saini HK, van Dongen S, Enright AJ: miRBase: tools for microRNA genomics. Nucleic Acids Res. 2008, 36: D154-158. 10.1093/nar/gkn221.
Article
CAS
PubMed
Google Scholar
Microcosm Targets. [http://www.ebi.ac.uk/enright-srv/microcosm/cgi-bin/targets/v5/search.pl]
Tirkkonen M, Kainu T, Loman N, Johannsson OT, Olsson H, Barkardottir RB, Kallioniemi OP, Borg A: Somatic genetic alterations in BRCA2-associated and sporadic male breast cancer. Genes Chromosomes Cancer. 1999, 24: 56-61. 10.1002/(SICI)1098-2264(199901)24:1<56::AID-GCC8>3.0.CO;2-X.
Article
CAS
PubMed
Google Scholar
Wang W: Emergence of a DNA-damage response network consisting of Fanconi anaemia and BRCA proteins. Nat Rev Genet. 2007, 8: 735-748.
Article
CAS
PubMed
Google Scholar
Chen F, Kamradt M, Mulcahy M, Byun Y, Xu H, McKay MJ, Cryns VL: Caspase proteolysis of the cohesin component RAD21 promotes apoptosis. J Biol Chem. 2002, 277: 16775-16781. 10.1074/jbc.M201322200.
Article
CAS
PubMed
Google Scholar
Martin SA, Ouchi T: BRCA1 phosphorylation regulates caspase-3 activation in UV-induced apoptosis. Cancer Res. 2005, 65: 10657-10662. 10.1158/0008-5472.CAN-05-2087.
Article
CAS
PubMed
Google Scholar
Xu H, Tomaszewski JM, McKay MJ: Can corruption of chromosome cohesion create a conduit to cancer?. Nat Rev Cancer. 2011, 11: 199-210. 10.1038/nrc3018.
Article
CAS
PubMed
Google Scholar
Dorsett D: Cohesin: genomic insights into controlling gene transcription and development. Curr Opin Genet Dev. 2011, 21: 199-206. 10.1016/j.gde.2011.01.018.
Article
CAS
PubMed
PubMed Central
Google Scholar
Mendes-Pereira AM, Sims D, Dexter T, Fenwick K, Assiotis I, Kozarewa I, Mitsopoulos C, Hakas J, Zvelebil M, Lord CJ, Ashworth A: Genome-wide functional screen identifies a compendium of genes affecting sensitivity to tamoxifen. Proc Natl Acad Sci USA. 2012, 109: 2730-2735. 10.1073/pnas.1018872108.
Article
CAS
PubMed
Google Scholar
van Agthoven T, Sieuwerts AM, Meijer D, Meijer-van Gelder ME, van Agthoven TL, Sarwari R, Sleijfer S, Foekens JA, Dorssers LC: Selective recruitment of breast cancer anti-estrogen resistance genes and relevance for breast cancer progression and tamoxifen therapy response. Endocr Relat Cancer. 2010, 17: 215-230. 10.1677/ERC-09-0062.
Article
CAS
PubMed
Google Scholar
Schuetz CS, Bonin M, Clare SE, Nieselt K, Sotlar K, Walter M, Fehm T, Solomayer E, Riess O, Wallwiener D, Kurek R, Neubauer HJ: Progression-specific genes identified by expression profiling of matched ductal carcinomas in situ and invasive breast tumors, combining laser capture microdissection and oligonucleotide microarray analysis. Cancer Res. 2006, 66: 5278-5286. 10.1158/0008-5472.CAN-05-4610.
Article
CAS
PubMed
Google Scholar
van Schooneveld E, Wouters M, Van der Auwera I, Peeters D, Huget P, van Dam PA, Vermeulen PB, Van Laere SJ, Dirix LY: Detection of circulating miRNAs in serum from patients with breast cancer and their association with the presence of metastatic disease. J Clin Oncol. 2011, 29: abstr 10506-
Google Scholar
Kozaki K, Imoto I, Mogi S, Omura K, Inazawa J: Exploration of tumor-suppressive microRNAs silenced by DNA hypermethylation in oral cancer. Cancer Res. 2008, 68: 2094-2105. 10.1158/0008-5472.CAN-07-5194.
Article
CAS
PubMed
Google Scholar
Shevde LA, Metge BJ, Mitra A, Xi Y, Ju J, King JA, Samant RS: Spheroid-forming subpopulation of breast cancer cells demonstrates vasculogenic mimicry via hsa-miR-299-5p regulated de novo expression of osteopontin. J Cell Mol Med. 2010, 14: 1693-1706.
Article
CAS
PubMed
Google Scholar
Hahnel A, Wichmann H, Kappler M, Kotzsch M, Vordermark D, Taubert H, Bache M: Effects of osteopontin inhibition on radiosensitivity of MDA-MB-231 breast cancer cells. Radiat Oncol. 2012, 5: 82-
Article
Google Scholar
Pang H, Cai L, Yang Y, Chen X, Sui G, Zhao C: Knockdown of osteopontin chemosensitizes MDA-MB-231 cells to cyclophosphamide by enhancing apoptosis through activating p38 MAPK pathway. Cancer Biother Radiopharm. 2011, 26: 165-173. 10.1089/cbr.2010.0838.
Article
PubMed
Google Scholar
Alli E, Sharma VB, Sunderesakumar P, Ford JM: Defective repair of oxidative DNA damage in triple-negative breast cancer confers sensitivity to inhibition of poly(ADP-ribose) polymerase. Cancer Res. 2009, 69: 3589-3596. 10.1158/0008-5472.CAN-08-4016.
Article
CAS
PubMed
PubMed Central
Google Scholar
Ashworth A: A synthetic lethal therapeutic approach: poly(ADP) ribose polymerase inhibitors for the treatment of cancers deficient in DNA double-strand break repair. J Clin Oncol. 2008, 26: 3785-3790. 10.1200/JCO.2008.16.0812.
Article
CAS
PubMed
Google Scholar