Figure 6From: Role of thioredoxin reductase 1 and thioredoxin interacting protein in prognosis of breast cancerERBB2-mediated altered expression of TXNRD1 and TXNIP and the association with prognosis. ERBB2 mediates upregulation of thioredoxin reductase 1 (TXNDR1) expression and downregulation of thioredoxin interacting protein (TXNIP) expression, which in turn are associated with bad prognosis in breast cancer. TXN, thioredoxin.Back to article page