First clinical results on the potential of intraoperative imaging for sentinel lymph node biopsy in breast cancer
© BioMed Central Ltd 2007
Received: 23 May 2007
Published: 19 June 2007
The growing interest in the sentinel lymph node (SLN) detection concept has led to the development of several prototypes of hand-held gamma cameras. After the first successful clinical trials with intraoperative imaging probes, the time has come to quantify the clinical benefit of these devices.
To compare the hand-held camera (POCI) with a lymphoscintigraphy in order to precisely localize SLNs in patients with breast cancer requiring SLN biopsy.
Results of SLN identification with lymphoscintigraphy and POCI
POCI camera the day before surgery
POCI intraoperative imager
These preliminary clinical results show that the POCI camera is able to predict the number and localization of breast cancer SLNs. The POCI camera appears to be a promising tool to complete or replace the preoperative standard lymphoscintigraphy, especially in surgical centers without an onsite nuclear medicine department.