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  1. Serial plasma samples from 1006 patients with breast cancer revealed: (i) no correlation of p53 autoantibody status with disease status at the time of sample collection, or with menopausal status at time of pr...

    Authors: Su Metcalfe, Terence K Wheeler, Sheila Picken, Susanne Negus and A Jo Milner
    Citation: Breast Cancer Research 2000 2:438
  2. Breast cancer mortality rates have shown only modest improvemen despite the advent of effective chemotherapeutic agents which have been administered to a large percentage of women with breast cancer. In an eff...

    Authors: Susan E Clare, Faina Nakhlis and John Carl Panetta
    Citation: Breast Cancer Research 2000 2:430
  3. Inflammatory breast cancer (IBC) is an aggressive form of locally advanced breast cancer (LABC) that effects approximately 5% of women with breast cancer annually in the USA. It is a clinically and pathologica...

    Authors: Celina G Kleer, Kenneth L van Golen and Sofia D Merajver
    Citation: Breast Cancer Research 2000 2:423
  4. During embryogenesis, the formation of primary vascular networks occurs via the processes of vasculogenesis and angiogenesis. In uveal melanoma, vasculogenic mimicry describes the 'embryonic-like' ability of a...

    Authors: Mary JC Hendrix, Elisabeth A Seftor, Dawn A Kirschmann and Richard EB Seftor
    Citation: Breast Cancer Research 2000 2:417
  5. The present is an overview of recent data that describes the genetic underpinnings of the suppression of cancer metastasis. Despite the explosion of new information about the genetics of cancer, only six human...

    Authors: Danny R Welch, Patricia S Steeg and Carrie W Rinker-Schaeffer
    Citation: Breast Cancer Research 2000 2:408
  6. Recent technological advances have led to an increasing ability to detect isolated tumour cells and groups of tumour cells in patients' blood, lymph nodes or bone marrow. However, the clinical significance of ...

    Authors: Ann F Chambers, George N Naumov, Sharon A Vantyghem and Alan B Tuck
    Citation: Breast Cancer Research 2000 2:400
  7. Computer-assisted mammography imaging comprises computer-based analysis of digitized images resulting in prompts aiding mammographic interpretation and computerized stereotactic localization devices which impr...

    Authors: Caroline RM Boggis and Susan M Astley
    Citation: Breast Cancer Research 2000 2:392
  8. BRCA1 and BRCA2 breast cancer susceptibility genes encode proteins, the normal cellular functions of which are complex and multiple, and germ-line mutations in individuals predispose both to breast and to ovaria...

    Authors: Dominique J Bernard-Gallon, Pierre Déchelotte, Cécile Vissac, Bénédicte Aunoble, Laetitia Cravello, Georges Malpuech and Yves-Jean Bignon
    Citation: Breast Cancer Research 2000 3:61
  9. Patients with abnormal breast findings (n = 413) were examined by mammography, sonography and magnetic resonance (MR) mammography; 185 invasive cancers, 38 carcinoma in situ and 254 benign tumours were confirmed ...

    Authors: Sabine Malur, Susanne Wurdinger, Andreas Moritz, Wolfgang Michels and Achim Schneider
    Citation: Breast Cancer Research 2000 3:55
  10. The present review addresses the capacity of optical imaging to resolve functional and molecular characteristics of breast cancer. We focus on recent developments in optical imaging that allow three-dimensiona...

    Authors: Vasilis Ntziachristos and Britton Chance
    Citation: Breast Cancer Research 2000 3:41
  11. The use of magnetic resonance spectroscopy (MRS) to investigate breast tumour biochemistry in vivo is reviewed. To this end, results obtained both from patients in vivo and from tumour extracts and model systems ...

    Authors: Sabrina M Ronen and Martin O Leach
    Citation: Breast Cancer Research 2000 3:36
  12. A variety of imaging technologies is being investigated as tools for studying gene expression in living subjects. Two technologies that use radiolabeled isotopes are single photon emission computed tomography ...

    Authors: Frank Berger and Sanjiv Sam Gambhir
    Citation: Breast Cancer Research 2000 3:28
  13. Four trials of high-dose chemotherapy with stem cell support in breast cancer in the adjuvant and metastatic settings have shown no long-term disease-free or overall survival gain. This relative failure of a s...

    Authors: Astrid Mayer and Helena Earl
    Citation: Breast Cancer Research 2000 3:8
  14. Breast tumor development and progression are thought to occur through a complex, multistep process, including oncogene activation (eg HER2/neu) and mutation or loss of tumor suppressor genes (eg p53). Determin...

    Authors: Zoe A Stewart and Jennifer A Pietenpol
    Citation: Breast Cancer Research 2000 3:5
  15. The breast myoepithelial cell is the Cinderella of mammary biology. Although its contribution to benign and some malignant pathologies is recognised, it has been largely neglected in molecular and biological s...

    Authors: Sunil R Lakhani and Michael J O'Hare
    Citation: Breast Cancer Research 2000 3:1

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