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The sialyl-glycolipid stage-specific embryonic antigen 4 marks a subpopulation of chemotherapy-resistant breast cancer cells with mesenchymal features

Chemotherapy resistance resulting in incomplete pathologic response is associated with high risk of metastasis and early relapse in breast cancer. The aim of this study was to identify and evaluate biomarkers ...

Authors: Andrea Aloia, Evgeniya Petrova, Stefan Tomiuk, Ute Bissels, Olivier Déas, Massimo Saini, Franziska Maria Zickgraf, Steve Wagner, Saskia Spaich, Marc Sütterlin, Andreas Schneeweiss, Manuel Reitberger, Silvia Rüberg, Bernhard Gerstmayer, David Agorku, Sebastian Knöbel…

Citation: Breast Cancer Research 2015 17:146

Content type: Research article Published on: 25 November 2015
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β2-adrenoceptor signaling regulates invadopodia formation to enhance tumor cell invasion

For efficient metastatic dissemination, tumor cells form invadopodia to degrade and move through three-dimensional extracellular matrix. However, little is known about the conditions that favor invadopodia for...

Authors: Sarah J. Creed, Caroline P. Le, Mona Hassan, Cindy K. Pon, Sabine Albold, Keefe T. Chan, Matthew E. Berginski, Zhendong Huang, James E. Bear, J. Robert Lane, Michelle L. Halls, Davide Ferrari, Cameron J. Nowell and Erica K. Sloan

Citation: Breast Cancer Research 2015 17:145

Content type: Research article Published on: 25 November 2015
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Erratum to: Quantitative assessment of background parenchymal enhancement in breast MRI predicts response to risk-reducing salpingo-oophorectomy: preliminary evaluation in a cohort of BRCA1/2 mutation carriers

Authors: Shandong Wu, Susan P. Weinstein, Michael J. DeLeo, Emily F. Conant, Jinbo Chen, Susan M. Domchek and Despina Kontos

Citation: Breast Cancer Research 2015 17:144

Content type: Erratum Published on: 24 November 2015

The original article was published in Breast Cancer Research 2015 17:67
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Mammographic density defined by higher than conventional brightness threshold better predicts breast cancer risk for full-field digital mammograms

When measured using the computer-assisted method CUMULUS, mammographic density adjusted for age and body mass index predicts breast cancer risk. We asked if new mammographic density measures defined by higher ...

Authors: Tuong Linh Nguyen, Ye Kyaw Aung, Christopher Francis Evans, Choi Yoon-Ho, Mark Anthony Jenkins, Joohon Sung, John Llewelyn Hopper and Yun-Mi Song

Citation: Breast Cancer Research 2015 17:142

Content type: Research article Published on: 18 November 2015
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Upregulation of EGFR signaling is correlated with tumor stroma remodeling and tumor recurrence in FGFR1-driven breast cancer

Despite advances in early detection and adjuvant targeted therapies, breast cancer is still the second most common cause of cancer mortality among women. Tumor recurrence is one of the major contributors to br...

Authors: Xue B. Holdman, Thomas Welte, Kimal Rajapakshe, Adam Pond, Cristian Coarfa, Qianxing Mo, Shixia Huang, Susan G. Hilsenbeck, Dean P. Edwards, Xiang Zhang and Jeffrey M. Rosen

Citation: Breast Cancer Research 2015 17:141

Content type: Research article Published on: 18 November 2015
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The benefit of HER2-targeted therapies on overall survival of patients with metastatic HER2-positive breast cancer – a systematic review

This study aimed at evaluating the overall survival (OS) gain associated with human epidermal growth factor receptor 2 (HER2)-directed therapies in patients with metastatic breast cancer (mBC).

Authors: Diogo Mendes, Carlos Alves, Noémia Afonso, Fátima Cardoso, José Luís Passos-Coelho, Luís Costa, Sofia Andrade and Francisco Batel-Marques

Citation: Breast Cancer Research 2015 17:140

Content type: Research article Published on: 17 November 2015
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Follow-up imaging of breast symptomatic patients: a waste of radiologist time?

Authors: Diana Dalgliesh, Alison Smith and Anjum Mahatma

Citation: Breast Cancer Research 2015 17(Suppl 1):P44

Content type: Poster presentation Published on: 5 November 2015

This article is part of a Supplement: Volume 17 Supplement 1
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The radiologist in the fast track breast clinic: the invisible man (woman)

Authors: Nicholas Ridley, Charlotte Jones, Nathan Coombs and Sarah Taylor

Citation: Breast Cancer Research 2015 17(Suppl 1):P43

Content type: Poster presentation Published on: 5 November 2015

This article is part of a Supplement: Volume 17 Supplement 1
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'Peace of mind'? Demand for breast imaging investigation following normal clinical examination: establishing the patient benefits and service implications for a symptomatic service

Authors: Miaad Al-Attar, Lubna Bashir, Lisa Grosvenor, Diane Lister, Elizabeth Denton, Moin Hoosein, Lakshmi Sundaram, Gayle McDonald and Niki Hartley

Citation: Breast Cancer Research 2015 17(Suppl 1):P42

Content type: Poster presentation Published on: 5 November 2015

This article is part of a Supplement: Volume 17 Supplement 1
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Breast cancer in women under 35 years

Authors: Kate Hunter, Deirdre Boyle, John Kavanagh, Yvonne Hanhauser, Elizabeth Connolly and Sylvia O'Keeffe

Citation: Breast Cancer Research 2015 17(Suppl 1):P41

Content type: Poster presentation Published on: 5 November 2015

This article is part of a Supplement: Volume 17 Supplement 1
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Breast pain in the over 40s: impact on imaging

Authors: Trupti Kulkarni and Andrew O'Connor

Citation: Breast Cancer Research 2015 17(Suppl 1):P40

Content type: Poster presentation Published on: 5 November 2015

This article is part of a Supplement: Volume 17 Supplement 1
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Prospective study looking at CT staging for metastases in early breast cancer

Authors: Michelle McMahon, Nisha Sharma and David Dodwell

Citation: Breast Cancer Research 2015 17(Suppl 1):P39

Content type: Poster presentation Published on: 5 November 2015

This article is part of a Supplement: Volume 17 Supplement 1
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Comparison of prognostic indices in symptomatic and screen-detected invasive breast cancer in Asian and Caucasian women

Authors: Andrew Steele, Anil Jain, Navneet Randhawa, Philip Foden and Julie Morris

Citation: Breast Cancer Research 2015 17(Suppl 1):P38

Content type: Poster presentation Published on: 5 November 2015

This article is part of a Supplement: Volume 17 Supplement 1
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A comparative study of pathological and prognostic differences in DCIS between Asian and Caucasian women

Authors: Raeesa Patel, Anil Jain and Philip Foden

Citation: Breast Cancer Research 2015 17(Suppl 1):P37

Content type: Poster presentation Published on: 5 November 2015

This article is part of a Supplement: Volume 17 Supplement 1
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Do bone scans add to CT in detecting skeletal metastases in breast cancer staging?

Authors: Anuradha Anand, Lekha Potti, Geoff Naisby, Sheetal Sharma and Alan Redman

Citation: Breast Cancer Research 2015 17(Suppl 1):P36

Content type: Poster presentation Published on: 5 November 2015

This article is part of a Supplement: Volume 17 Supplement 1
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Local experience of referral for breast assessment resulting from incidental findings on CT and PET-CT studies over a 5-year period

Authors: Richard Sidebottom, Jean Lee, Shaheel Bhuva and Vaishali Parulekar

Citation: Breast Cancer Research 2015 17(Suppl 1):P35

Content type: Poster presentation Published on: 5 November 2015

This article is part of a Supplement: Volume 17 Supplement 1
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Role of mammographic templates in managing ever increasing workloads

Authors: Anne Nielsen Moody, Maggie Fletcher and Nisha Sharma

Citation: Breast Cancer Research 2015 17(Suppl 1):P34

Content type: Poster presentation Published on: 5 November 2015

This article is part of a Supplement: Volume 17 Supplement 1
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Breast biopsy in patients on anti-coagulants: is new guidance needed?

Authors: Trupti Kulkarni and Andrew O'Connor

Citation: Breast Cancer Research 2015 17(Suppl 1):P33

Content type: Poster presentation Published on: 5 November 2015

This article is part of a Supplement: Volume 17 Supplement 1
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Safety of vacuum-assisted biopsy/mammatome guided, non-operative management of B3 lesions with atypia: a 7-year follow-up study

Authors: Alex Wilkins, Peter Kneeshaw, Penelope McManus, Kartikae Grover, Caroline Bradley, Ayesha Rahman and Anne Hubbard

Citation: Breast Cancer Research 2015 17(Suppl 1):P31

Content type: Poster presentation Published on: 5 November 2015

This article is part of a Supplement: Volume 17 Supplement 1
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Quantitative study: should vacuum-assisted biopsy be the first biopsy approach in breast interventional techniques in stereotactic guided microcalcifications rather than 14 gauge core needle biopsy?

Authors: Anuma Shrestha, Louise Wilkinson, Rosalind Given-Wilson and Judi Curtis

Citation: Breast Cancer Research 2015 17(Suppl 1):P29

Content type: Poster presentation Published on: 5 November 2015

This article is part of a Supplement: Volume 17 Supplement 1
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The 3.5-year to 13.5-year follow up of 137 lesions of uncertain malignant potential (B3 lesions) diagnosed by vacuum-assisted biopsy alone

Authors: Karen Mullin, Anne Turnbull, Sharma Puri and Mark Bagnall

Citation: Breast Cancer Research 2015 17(Suppl 1):P28

Content type: Poster presentation Published on: 5 November 2015

This article is part of a Supplement: Volume 17 Supplement 1
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Handheld ultrasound-guided 20 mm basket Intact breast lesion excision system biopsy for excision of benign breast lesions

Authors: Simon Lowes, Alice Leaver, Alice Townend, Jackie Westgarth, Peter Newton, Dianne Hemming and Alan Redman

Citation: Breast Cancer Research 2015 17(Suppl 1):P27

Content type: Poster presentation Published on: 5 November 2015

This article is part of a Supplement: Volume 17 Supplement 1
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Does tomosynthesis increase confidence in grading the suspicious appearance of a lesion? An audit of cancers diagnosed in the assessment clinic using tomosynthesis: initial experience at Avon Breast Screening Unit

Authors: Gillian Clark and Alexandra Valencia

Citation: Breast Cancer Research 2015 17(Suppl 1):P25

Content type: Poster presentation Published on: 5 November 2015

This article is part of a Supplement: Volume 17 Supplement 1
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Impact of index of multiple deprivation and ethnicity on breast screening uptake in the North West of England

Authors: Jayeshwaraj Bhola, Anil Jain and Philip Foden

Citation: Breast Cancer Research 2015 17(Suppl 1):P24

Content type: Poster presentation Published on: 5 November 2015

This article is part of a Supplement: Volume 17 Supplement 1
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Outcome of ultrasound of the mammographically normal contralateral breast in patients recalled to the screening assessment clinic

Authors: Preet Hamilton, Simon Lowes, Sheetal Sharma, Alicia Wright and Alice Leaver

Citation: Breast Cancer Research 2015 17(Suppl 1):P23

Content type: Poster presentation Published on: 5 November 2015

This article is part of a Supplement: Volume 17 Supplement 1
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Audit of high prevalent breast screening recall rates: Torbay Hospital

Authors: Alexander Crowther and Rebecca Green

Citation: Breast Cancer Research 2015 17(Suppl 1):P22

Content type: Poster presentation Published on: 5 November 2015

This article is part of a Supplement: Volume 17 Supplement 1
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A review of BRCA gene carrier demographics in Wales

Authors: Tom Evans, Jenny Long, Georgina Devenish, Mike Lewis, Damian Bailey, Kate Gower Thomas and Alexandra Murray

Citation: Breast Cancer Research 2015 17(Suppl 1):P21

Content type: Poster presentation Published on: 5 November 2015

This article is part of a Supplement: Volume 17 Supplement 1
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Diagnostic implications of digital breast tomosynthesis in symptomatic patients

Authors: Sanjeeva Ramasundara, Lorraine Tucker, Matthew Wallis, Peter Britton, Penny Moyle, Kethryn Taylor, Ruchi Sinnatamby, Alan Freeman, Matthew Gaskarth and Fiona Gilbert

Citation: Breast Cancer Research 2015 17(Suppl 1):P20

Content type: Poster presentation Published on: 5 November 2015

This article is part of a Supplement: Volume 17 Supplement 1
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A perceptual aid to delineating the extent of potential mammographic abnormalities

Authors: Arul Selvan, Yan Chen and Alastair Gale

Citation: Breast Cancer Research 2015 17(Suppl 1):P19

Content type: Poster presentation Published on: 5 November 2015

This article is part of a Supplement: Volume 17 Supplement 1
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Initial outcome of contrast-enhanced spectral mammography in lesion characterisation in the mammographically dense breast

Authors: Zeiad Hussain, Peter Duggan, Julie Scudder and Sarah McWilliams

Citation: Breast Cancer Research 2015 17(Suppl 1):P18

Content type: Poster presentation Published on: 5 November 2015

This article is part of a Supplement: Volume 17 Supplement 1
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Positive predictive value of mammographic features on digital breast tomosynthesis

Authors: Bhavna Batohi, Juliet Morel, Reema Wasan, Asif Iqbal, David Evans, Jane Goligher, Michael Michell, Clare Peacock, Rumana Rahim and Keshthra Satchithananda

Citation: Breast Cancer Research 2015 17(Suppl 1):P16

Content type: Poster presentation Published on: 5 November 2015

This article is part of a Supplement: Volume 17 Supplement 1
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Comparative study of radiation dose between tomosynthesis and standard compression views in mammography

Authors: Alice Bannister and Julie Scudder

Citation: Breast Cancer Research 2015 17(Suppl 1):P15

Content type: Poster presentation Published on: 5 November 2015

This article is part of a Supplement: Volume 17 Supplement 1
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Contrast-enhanced spectral mammography: what is the 'added value' in a symptomatic setting? Initial findings from a UK centre

Authors: Sarah Tennant, Eleanor Cornford, Jonathan James, Helen Burrell, Lisa Hamilton and Yan Chen

Citation: Breast Cancer Research 2015 17(Suppl 1):P14

Content type: Poster presentation Published on: 5 November 2015

This article is part of a Supplement: Volume 17 Supplement 1
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Can public consultation effectively optimise the design of a patient information leaflet about breast magnetic resonance imaging?

Authors: Lyn Jones, Anna Mankelow, Joanne Robson, Anjum Mahatma, Alice Pocklington and Alexandra Valencia

Citation: Breast Cancer Research 2015 17(Suppl 1):P13

Content type: Poster presentation Published on: 5 November 2015

This article is part of a Supplement: Volume 17 Supplement 1
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MRI guided breast biopsy: initial experience of service expansion in West Midlands

Authors: Muthyala Sreenivas and Vandana Gaur

Citation: Breast Cancer Research 2015 17(Suppl 1):P12

Content type: Poster presentation Published on: 5 November 2015

This article is part of a Supplement: Volume 17 Supplement 1
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Comparison of MRI and digital breast tomosynthesis in the preoperative evaluation of multifocal breast cancer

Authors: Bhavna Batohi, Valeria Vinci, Clare Peacock, Michael Michell, Asif Iqbal, David Evans, Juliet Morel, Keshthra Satchithananda, Reema Wasan and Rumana Rahim

Citation: Breast Cancer Research 2015 17(Suppl 1):P11

Content type: Poster presentation Published on: 5 November 2015

This article is part of a Supplement: Volume 17 Supplement 1
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Is pretreatment assessment of the contralateral breast with MRI useful following a new diagnosis of invasive lobular cancer?

Authors: Harriet Russell, Rebecca Geach, Iain Lyburn and Helen Massey

Citation: Breast Cancer Research 2015 17(Suppl 1):P10

Content type: Poster presentation Published on: 5 November 2015

This article is part of a Supplement: Volume 17 Supplement 1
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Use of MRI to predict response following neoadjuvant chemotherapy for breast cancer: how accurately can it guide surgical choice?

Authors: Sue Tan, Simon Lowes, Carol Ellen Holmes, Nidhi Sibal, Lesley McLean and Nerys Forester

Citation: Breast Cancer Research 2015 17(Suppl 1):P9

Content type: Poster presentation Published on: 5 November 2015

This article is part of a Supplement: Volume 17 Supplement 1
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MRI evaluation of multifocality and contralateral disease in lobular breast cancer: what can we learn from one region's experience?

Authors: Claire Magee and Keith Lowry

Citation: Breast Cancer Research 2015 17(Suppl 1):P8

Content type: Poster presentation Published on: 5 November 2015

This article is part of a Supplement: Volume 17 Supplement 1
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Use of preoperative breast MRI to determine disease extent

Authors: Nicky Dineen, Jennifer Weeks, Ruxandra Pietrosanu, Karina Cox and Pippa Mills

Citation: Breast Cancer Research 2015 17(Suppl 1):P7

Content type: Poster presentation Published on: 5 November 2015

This article is part of a Supplement: Volume 17 Supplement 1
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Correlation of post-neoadjuvant chemotherapy response on MRI with final histology in breast cancer patients

Authors: Anjum Mahatma, Lyn Jones and Alexandra Valencia

Citation: Breast Cancer Research 2015 17(Suppl 1):P6

Content type: Poster presentation Published on: 5 November 2015

This article is part of a Supplement: Volume 17 Supplement 1
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Informed choice and consent among women attending for breast screening in the UK: data from a qualitative study

Authors: Patsy Whelehan, Andrew Evans and Gozde Ozakinci

Citation: Breast Cancer Research 2015 17(Suppl 1):O6

Content type: Oral presentation Published on: 5 November 2015

This article is part of a Supplement: Volume 17 Supplement 1
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Preoperative identification and biopsy of sentinel lymph nodes using contrast-enhanced ultrasound: the Tunbridge Wells experience

Authors: Tania De'Silva, Mohamed Hashem, Nick Wakeham, Sarah Kirwan, Neal Chayya, Pippa Mills and Karina Cox

Citation: Breast Cancer Research 2015 17(Suppl 1):P5

Content type: Poster presentation Published on: 5 November 2015

This article is part of a Supplement: Volume 17 Supplement 1
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Use of sulphur hexafluoride microbubbles injection to identify the sentinel lymph node in breast cancer patients: initial experience in a UK breast unit

Authors: Alice Leaver, Simon Lowes, Peter Newton, Linsley Lunt, Anuradha Anand, Linda Hutchinson, Sally Athey, Amanda Jane Potterton, Sheetal Sharma and Alan Redman

Citation: Breast Cancer Research 2015 17(Suppl 1):P4

Content type: Poster presentation Published on: 5 November 2015

This article is part of a Supplement: Volume 17 Supplement 1
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Breast tumour localisation using Iodine seeds in the UK: the first 100 patients

Authors: Nidhi Sibal and Nerys Forester

Citation: Breast Cancer Research 2015 17(Suppl 1):O4

Content type: Oral presentation Published on: 5 November 2015

This article is part of a Supplement: Volume 17 Supplement 1
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Evaluation of the use of microbubbles in the ultrasound assessment of the axilla in breast cancer patients

Authors: Nisha Sharma, Isobel Haigh, Rebecca Millican-Slater and Benjamin Dessauvagie

Citation: Breast Cancer Research 2015 17(Suppl 1):P3

Content type: Poster presentation Published on: 5 November 2015

This article is part of a Supplement: Volume 17 Supplement 1
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Breast density measurements with ultrasound tomography: a comparison with non-contrast MRI

Authors: Elizabeth O'Flynn, Jeremie Fromageau, Minty Ledger, Alessandro Messa, Ashley D'Aquino, Minouk Schoemaker, Maria Schmidt, Neb Duric, Anthony Swerdlow and Jeff Bamber

Citation: Breast Cancer Research 2015 17(Suppl 1):O3

Content type: Oral presentation Published on: 5 November 2015

This article is part of a Supplement: Volume 17 Supplement 1
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Accuracy of axillary nodal ultrasound and ultrasound fine needle aspiration/core biopsy in the preoperative staging of patients with invasive breast cancer

Authors: William Cheung, Suzanne McLenachan, Gauripriya Babu and Melanie Smith

Citation: Breast Cancer Research 2015 17(Suppl 1):P2

Content type: Poster presentation Published on: 5 November 2015

This article is part of a Supplement: Volume 17 Supplement 1
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Breast screening interval and the characteristics of screen-detected cancers

Authors: Carl A Tupper, Anthony J Maxwell, Susan Astley, Megan Bydder, Soujanya Gadde, Elaine Harkness, Yit Y Lim, Mary Wilson and Julie Morris

Citation: Breast Cancer Research 2015 17(Suppl 1):O2

Content type: Oral presentation Published on: 5 November 2015

This article is part of a Supplement: Volume 17 Supplement 1
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Sensitivity of US and FNAC for staging of the axilla in patients presenting with symptomatic breast cancer

Authors: Diane Lister, Miaad Al-Attar, Elizabeth Denton, Lisa Grosvenor, Gayle McDonald and Dave Purnell

Citation: Breast Cancer Research 2015 17(Suppl 1):P1

Content type: Poster presentation Published on: 5 November 2015

This article is part of a Supplement: Volume 17 Supplement 1
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