Fig. 4

Associations of baseline comorbidities and prior non-cancer chronic medication use with adherence to adjuvant endocrine therapy 4,353 Danish premenopausal breast cancer patients diagnosed 2002–2011. Exposure reference groups were set to groups with the highest number of cohort members, except for estimates comparing any versus no prior medication use. The ‘None’ category was set as the reference a priori. Abbreviations: OR, odds ratio; CI, confidence interval. Each model’s adjustment factors were directed by Directed Acyclic Graphs (Additional file 1: S2). ^aAssociations between Charlson Comorbidity Index score and adherence adjusted for age and education level. ^bAssociations between prior medication use (and all selected medications) and adherence adjusted for age, Charlson Comorbidity Index score, household income, cohabitation status, and education level