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Table 4 Baseline characteristics according to axillary lymph node metastasis

From: Selective omission of sentinel lymph node biopsy in mastectomy for ductal carcinoma in situ: identifying eligible candidates

Variables

Node-negative (n = 368)

Node-positive (n = 17)

 

N

(%)

N

(%)

p-value

Age (y)

    

0.032

 ≤ 50

206

56

14

82.4

 

 > 50

162

44

3

17.6

 

Palpable mass or bloody nipple discharge

    

0.197

 No

210

57.1

7

41.2

 

 Yes

158

42.9

10

58.8

 

Clinical tumor size, median (range), cm

4.5 (0.5–12.9)

5.1 (1.5–9.6)

0.112

Suspicious axillary lymph node on radiologic evaluation

    

< 0.001

 No

291

79.1

5

29.4

 

 Yes

77

20.9

12

70.6

 

Suspicious microcalcification on radiologic evaluation

    

> 0.999

 No

114

31

5

29.4

 

 Yes

254

69

12

70.6

 

Nuclear grade*,†

    

0.489‡

 Low

52

16.8

1

7.7

 

 Intermediate

177

57.1

7

53.8

 

 High

81

26.1

5

38.5

 

Comedo necrosis*,†

    

> 0.999‡

 No

107

36.4

4

36.4

 

 Yes

187

63.6

7

63.6

 

Hormone receptor§

    

0.500

 Negative

96

26.1

3

17.6

 

 Positive

269

73.1

13

76.5

 

HER2§

    

0.071

 Negative

240

65.2

14

82.4

 

 Positive

125

34.0

2

11.8

 

Ki-67 (%) §

    

0.381

 < 14%

264

71.7

10

58.8

 

 ≥ 14%

100

27.2

6

35.3

 
  1. *Missing values
  2. †Values assessed in biopsy specimens
  3. ‡The p-value was determined using Fisher’s exact test
  4. §Values assessed in surgical specimens