Variables |  | Total (n = 385) | |
---|---|---|---|
N | (%) | ||
Preoperative factors | Age (years) | Â | Â |
 | ≤ 50 | 220 | 57.1 |
 | > 50 | 165 | 42.9 |
 | Clinical tumor size, median (range), cm | 4.5 (0.5–12.9) | |
 | ≤ 2 cm | 60 | 15.6 |
 | 2 –5 cm | 172 | 44.7 |
 | > 5 cm | 153 | 39.7 |
 | Palpable mass or bloody nipple discharge |  |  |
 | No | 217 | 56.4 |
 | Yes | 168 | 43.6 |
 | Suspicious axillary lymph node on radiologic evaluation |  |  |
 | No | 296 | 76.9 |
 | Yes | 89 | 23.1 |
 | Suspicious microcalcification on radiologic evaluation |  |  |
 | No | 119 | 30.9 |
 | Yes | 266 | 69.1 |
 | Nuclear grade*,†|  |  |
 | Low | 53 | 16.4 |
 | Intermediate | 184 | 57 |
 | High | 86 | 26.6 |
 | Comedo necrosis*,†|  |  |
 | No | 111 | 36.4 |
 | Yes | 194 | 63.6 |
Postoperative factors | Pathologic DCIS size, median (range), cm | 4.15 (0.1–20) | |
 | Nuclear grade‡ |  |  |
 | Low | 28 | 7.3 |
 | Intermediate | 219 | 56.9 |
 | High | 138 | 35.8 |
 | Comedo necrosis*,‡ |  |  |
 | No | 91 | 23.9 |
 | Yes | 290 | 76.1 |
 | Hormone receptor *,‡ |  |  |
 | Negative | 99 | 25.7 |
 | Positive | 282 | 73.2 |
 | HER2*,‡ |  |  |
 | Negative | 254 | 66.0 |
 | Positive | 127 | 33.0 |
 | Ki-67 (%)*, ‡ |  |  |
 | < 14 | 274 | 72.1 |
 | ≥ 14 | 106 | 27.9 |