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Table 1 Baseline characteristics

From: Selective omission of sentinel lymph node biopsy in mastectomy for ductal carcinoma in situ: identifying eligible candidates

Variables

 

Total (n = 385)

N

(%)

Preoperative factors

Age (years)

  
 

≤ 50

220

57.1

 

> 50

165

42.9

 

Clinical tumor size, median (range), cm

4.5 (0.5–12.9)

 

≤ 2 cm

60

15.6

 

2 –5 cm

172

44.7

 

> 5 cm

153

39.7

 

Palpable mass or bloody nipple discharge

  
 

No

217

56.4

 

Yes

168

43.6

 

Suspicious axillary lymph node on radiologic evaluation

  
 

No

296

76.9

 

Yes

89

23.1

 

Suspicious microcalcification on radiologic evaluation

  
 

No

119

30.9

 

Yes

266

69.1

 

Nuclear grade*,†

  
 

Low

53

16.4

 

Intermediate

184

57

 

High

86

26.6

 

Comedo necrosis*,†

  
 

No

111

36.4

 

Yes

194

63.6

Postoperative factors

Pathologic DCIS size, median (range), cm

4.15 (0.1–20)

 

Nuclear grade‡

  
 

Low

28

7.3

 

Intermediate

219

56.9

 

High

138

35.8

 

Comedo necrosis*,‡

  
 

No

91

23.9

 

Yes

290

76.1

 

Hormone receptor *,‡

  
 

Negative

99

25.7

 

Positive

282

73.2

 

HER2*,‡

  
 

Negative

254

66.0

 

Positive

127

33.0

 

Ki-67 (%)*, ‡

  
 

< 14

274

72.1

 

≥ 14

106

27.9

  1. *Missing values
  2. †Values assessed in biopsy specimens
  3. ‡Values assessed in surgical specimens
  4. DCIS = ductal carcinoma in situ, HR = hormone receptor, HER2 = human epidermal growth factor receptor 2