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Fig. 5 | Breast Cancer Research

Fig. 5

From: Exploring the dynamic interplay between exosomes and the immune tumor microenvironment: implications for breast cancer progression and therapeutic strategies

Fig. 5

As an alternate delivery mechanism for tumor antigens, DC-derived exosomes, also known as Dex, have been attracting a lot of attention recently. Antigen-presenting particles like MHC-I and MHC-II, CD80 and CD86, and Hsp 70 and 90 are carried by dex in the body. This enables the DC to increase Tcell activity towards tumor tissue areas (a). NK-derived exosomes, also known as NK-Exos, are vesicles that include NK cells’ prototype markers, such as CD56, together with cytotoxic proteins like FasL and perforin. This enables the NK cells to guide their cytolytic activity towards tumor tissue areas (b)

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Breast Cancer Research

ISSN: 1465-542X

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