Fig. 1
Relationship between 99mTc-NM-02 SUVmax and HER2 IHC scores (A) and HER2 status (B) in the primary lesions of the newly diagnosed group. Relationship between 99mTc-NM-02 SUVmax and HER2 status in the metastases of the newly diagnosed group (C). Relationship between 99mTc-NM-02 SUVmax and HER2 status in the primary lesions (D) and metastases (E) of the treated group; a: seven HER2-positive patients in the newly diagnosed group, b: six patients in the treated group, c: five patients with high HER2 expression (HER2 2 + and 3+) in the treated group, d: four HER2-positive patients in the treated group, e: three HER2-positive patients with effective HER2-targeted therapy in the treated group. The 99mTc-NM-02 SUVmax and visual interpretation in all lesions at 1 and 2 h post-injection (F). The red line indicates a proposed threshold at SUVmax = 1.5 for discriminating HER2-positive and HER2-negative imaging