Table 2 Correlation of the expression of TMEM120B with clinicopathological features in 140 cases of breast cancer
Clinicopathological | Total TMEM120B | Cytosolic expression | Nuclear expression | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
factors | N | (+) | (-) | χ2 | P | N | (+) | (-) | P | N | (+) | (-) | P |
Age (years) | |||||||||||||
<51 | 74 | 37 | 37 | 0.032 | 0.867 | 70 | 34 | 36 | 0.727 | 4 | 3 | 1 | 0.524 |
≥51 | 66 | 34 | 32 | 61 | 32 | 29 | 5 | 2 | 3 | ||||
TNBC | |||||||||||||
Yes | 63 | 33 | 30 | 0.127 | 0.737 | 58 | 31 | 27 | 0.599 | 5 | 2 | 3 | 0.524 |
No | 77 | 38 | 39 | 73 | 35 | 38 | 4 | 3 | 1 | ||||
TNM classification | |||||||||||||
I + II | 95 | 41 | 54 | 6.751 | 0.011 | 89 | 38 | 51 | 0.015 | 6 | 3 | 3 | 1.000 |
III | 45 | 30 | 15 | 42 | 28 | 14 | 3 | 2 | 1 | ||||
Lymph node metastasis | |||||||||||||
Positive | 55 | 36 | 19 | 7.875 | 0.006 | 50 | 33 | 17 | 0.007 | 5 | 3 | 2 | 1.000 |
Negative | 85 | 35 | 50 | 81 | 33 | 48 | 4 | 2 | 2 | ||||
Subcellular localization | |||||||||||||
Cytoplasm | 131 | 66 | 65 | 0.090 | 1.000 | ||||||||
Nucleus | 9 | 5 | 4 | ||||||||||