Fig. 2

TNBC cells have different metastatic potentials to the lung A Representative tissue sections stained with H&E, obtained from lungs of mice 9 weeks after injection of TNBC cells in their 4th left mammary gland. Scale bar = 500 μm Inset scale bar = 500 μm. B Number of mice that developed lung metastases for each cell line. C The number of metastases per lung for each cell line and D Metastatic burden in lungs (ratio of the number of metastases in the lungs to the primary tumor volume) E Average size of each lung metastasis. Data are shown as mean with SEM 231 n = 6, 468 n = 10, BT549 n = 8, BT20 n = 9, SUM159 n = 9, Hs578T n = 10 animals/group. Significance was determined using a one-way ANOVA with Tukey’s multiple comparison test comparing each cell line to every other cell line. Significance (p < 0.05) is denoted by a letter corresponding to each cell line tested, 231 (a), 468 (b), BT549 (c), BT20 (d), SUM159 (e), Hs578T (f)