Table 1 Miller–Payne grading system
Miller–Payne grading | Explanation |
|---|---|
Grade 1 | No change or some alteration to individual malignant cells but no reduction in overall cellularity |
Grade 2 | A minor loss of tumor cells but overall cellularity still high; up to 30% loss |
Grade 3 | Between an estimated 30% and 90% reduction in tumor cells |
Grade 4 | A marked disappearance of tumor cells such that only small clusters or widely dispersed individual cells remain; more than 90% loss of tumor cells |
Grade 5 | No malignant cells identifiable in sections from the site of the tumor; only vascular fibroelastotic stroma remains often containing macrophages. However, ductal carcinoma in situ (DCIS) may be present |