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Fig. 3 | Breast Cancer Research

Fig. 3

From: c-MET-positive circulating tumor cells and cell-free DNA as independent prognostic factors in hormone receptor-positive/HER2-negative metastatic breast cancer

Fig. 3

Progression impact of ESR1 and PIK3CA concentration and mutations detected in cell-free DNA (cfDNA) samples. A Schematic diagram of the cfDNA analysis workflow. B Correlations between ESR1 template copies/mL plasma and PIK3CA template copies/mL plasma. Kaplan–Meier analysis of PFS by C cfDNA concentration in HR+/HER2− mBC, D cfDNA concentration in HR+/HER2+ mBC, E ESR1 hotspot mutation in HR+/HER2− mBC, and F PIK3CA hotspot mutation in HR+/HER2− mBC. HR, hormone receptor; mBC, metastatic breast cancer; PFS, Progression-free survival

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Breast Cancer Research

ISSN: 1465-542X

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