Tumor | GATA3 | ER | PR | Keratin 5 | Keratin 14 | HER2 |
|---|
CAF1 | + | + | − | − | − | Low |
CAF2 | + | + | + | − | − | Low |
CAF3 | + | + | − | − | − | Low |
- Breast cancer subtype determination was performed by peroxidase immunohistochemistry on cryosectioned tissue. Tumors were considered positive (+) or negative (−) if more or less than 1% of the neoplastic cells were reactive with an antibody, respectively. Estrogen receptor (ER) was positive in more than 50% of neoplastic cells in CAF1, CAF2 and CAF3 tumors. Intensity of HER2 stainings was evaluated against control tissue with known high and low expression levels of HER2. GATA3: Gata binding protein 3. PR: Progesterone receptor. HER2: Human epidermal growth factor receptor 2
