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Table 5 Patient profiles by OS status at 7.5 years (N = 475)

From: Machine learning prediction of pathological complete response and overall survival of breast cancer patients in an underserved inner-city population

Patient characteristics

N (%)

% OS

% no OS

p value

All patients

475 (100%)

82.9

17.1

–

Age, years (median 55.7 [IQR 17.57])

0.04

 ≥ 50

319 (67.2%)

80.3

19.7

 < 50

156 (32.8%)

88.5

11.5

Race (n, %)

0.03

 Hispanic white

96 (20.2%)

86.5

13.5

 Non-Hispanic white

64 (13.4%)

93.8

6.2

 Black

263 (55.4%)

79.1

20.9

 Asian

22 (4.6%)

90.9

9.1

 Other

30 (6.3%)

76.7

23.3

Ethnicity (n, %)

0.53

 Hispanic

164 (34.5%)

84.8

15.2

 Not Hispanic

311 (65.5%)

82.0

18.0

Clinical T-stage (n, %)

< 0.0001

 T1

66 (14.0%)

89.4

10.6

 T2

240 (51.1%)

89.6

10.4

 T3 and T4

164 (34.9%)

71.3

28.7

Clinical N Stage (n, %)

< 0.001

 N0

157 (33.0%)

91.7

8.3

 N1

243 (51.2%)

81.1

18.9

 N2

37 (7.8%)

62.2

37.8

 N3

38 (8.0%)

81.6

18.4

Nottingham grade (n, %)

0.92

 Grade 1

5 (1.2%)

80.0

20.0

 Grade 2

129 (31.5%)

83.7

16.3

 Grade 3

276 (67.3%)

80.4

19.6

Tumor subtype groups (n, %)

 < 0.001

 ER−/HER2+ (± PR+)

69 (15.1%)

87.0

13.0

 ER+/HER2+ (± PR+)

87 (19.0%)

90.8

9.2

 ER+/HER2− (± PR+)

130 (28.4%)

88.5

11.5

 ER−/HER2− (PR−) (triple negative)

171 (37.4%)

72.5

27.5

BPE Pre-NAC (n, %)

0.89

 Mild

163 (63.0%)

89.0

11.0

 Moderate

83 (32.0%)

88.0

12.0

 Marked

13 (5.0%)

92.3

7.7

MRI tumor size (LD, cm) (n, %)

0.15

 Small (≤ 2)

38 (15.8%)

92.1

7.9

 Medium (> 2 to 5)

148 (61.7%)

90.5

9.5

 Large (> 5)

54 (22.5%)

81.5

18.5

PCR

 < 0.0001

 Yes

100 (22.5%)

95.4

4.6

 No

345 (77.5%)

78.3

21.7

Annual income

0.39

 First quintile ($21,846.00–$34.860.00)

87 (21.5%)

90.8

9.2

 Second quintile ($34,860.00–$42,639.00)

100 (24.7%)

87.0

13.0

 Third quintile ($42,639.00–$58,814.20)

55 (13.6%)

89.1

10.9

 Fourth quintile ($58,814.20–$70,107.00)

81 (20.0%)

92.6

7.4

 Fifth quintile ($70,107.00–$218,493.00)

82 (20.2%)

95.1

4.9

Insurance type

0.0002

 Private

139 (34.5%)

96.2

3.8

 Medicaid

209 (51.9%)

88.5

11.5

 Medicare

51 (12.6%)

76.5

23.5

 Uninsured

4 (1.0%)

100.0

0.0

  1. p values indicate comparison between OS versus non-OS (7.5 years). Note that only 4 patients were uninsured and were included in the insurance status section. Note there was no missing OS data