Table 1 Patient profiles by pCR status (N = 475)
Patient characteristics | N (%) | % pCR | % no pCR | p value |
|---|---|---|---|---|
All patients with pCR data | 475 (100%) | 27.4% | 72.6% | – |
Age, years (median 55.7 [IQR 17.57]) | 0.20 | |||
 ≥ 50 | 319 (67.2%) | 25.4% | 74.6% | |
 < 50 | 156 (32.8%) | 31.4% | 68.6% | |
Race (n, %) | 0.87 | |||
 Hispanic white | 96 (20.2%%) | 25.0% | 75.0% | |
 Non-Hispanic white | 64 (13.5%) | 21.9% | 78.1% | |
 Black | 263 (55.4%) | 28.5% | 71.5% | |
 Asian | 22 (4.6%) | 31.8% | 68.2% | |
 Other | 30 (6.3%) | 33.3% | 66.7% | |
Ethnicity (n, %) | 1.0 | |||
 Hispanic | 164 (34.5%) | 27.4% | 72.6% | |
 Not Hispanic | 311 (65.5%) | 27.3% | 72.7% | |
Clinical T-stage (n, %) | 0.09 | |||
 T1 | 66 (14.0%) | 30.0% | 70.0% | |
 T2 | 240 (51.1%) | 31.0% | 69.0% | |
 T3 and T4 | 176 (34.9%) | 21.3% | 78.7% | |
Clinical N Stage (n, %) | 0.31 | |||
 N0 | 157 (33.0%) | 32.5% | 67.5% | |
 N1 | 243 (51.2%) | 24.7% | 75.3% | |
 N2 | 37 (7.8%) | 21.6% | 78.4% | |
 N3 | 38 (8.0%) | 28.9% | 71.1% | |
Nottingham grade (n, %) | 0.09 | |||
 Grade 1 | 5 (1.2%) | 0.0% | 100.0% | |
 Grade 2 | 129 (31.5%) | 21.7% | 78.3% | |
 Grade 3 | 276 (67.3%) | 29.7% | 70.3% | |
Tumor subtype groups (n, %) | < 0.001 | |||
 ER−/HER2+ (± PR+) | 69 (15.1%) | 56.5% | 43.5% | |
 ER+/HER2+ (± PR+) | 87 (19.0%) | 23.0% | 77.0% | |
 ER+/HER2− (± PR+) | 130 (28.4%) | 8.5% | 91.5% | |
 ER−/HER2− (PR−) (triple negative) | 171 (37.4%) | 31.0% | 69.0% | |
BPE pre-NAC (n, %) | 0.009 | |||
 Mild | 163 (63.0%) | 35.6% | 64.4% | |
 Moderate | 83 (32.0%) | 24.1% | 75.9% | |
 Marked | 13 (5.0%) | 0.0% | 100.0% | |
MRI tumor size (LD, cm) (n, %) | 0.003 | |||
 Small (≤ 2) | 38 (15.8%) | 34.2% | 65.8% | |
 Medium (> 2 to 5) | 148 (61.7%) | 35.1% | 64.9% | |
 Large (> 5) | 54 (22.5%) | 11.1% | 88.9% | |
Annual income | 0.77 | |||
 First quintile ($21,846.00–$34.860.00) | 87 (21.5%) | 33.3% | 66.7% | |
 Second quintile ($34,860.00–$42,639.00) | 100 (24.7%) | 25.0% | 75.0% | |
 Third quintile ($42,639.00–$58,814.20) | 55 (13.6%) | 29.1% | 70.9% | |
 Fourth quintile ($58,814.20–$70,107.00) | 81 (20.0%) | 27.2% | 72.8% | |
 Fifth quintile ($70,107.00–$218,493.00) | 82 (20.2%) | 30.5% | 69.5% | |
Insurance type | 0.58 | |||
 Private | 139 (34.5%) | 28.1% | 71.9% | |
 Medicaid | 209 (51.9%) | 30.6% | 69.4% | |
 Medicare | 51 (12.7%) | 23.5% | 76.5% | |
 Uninsured | 4 (1.0%) | 50% | 50.0% | |