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Table 1 Demographic and disease characteristics before and after IPTW

From: Prognostic value of baseline neutrophil/lymphocyte ratio in HER2-positive metastatic breast cancer: exploratory analysis of data from the CLEOPATRA trial

Characteristics

TH group (n = 384)

THP group (n = 396)

Low

High

P value

PS weighted P

Low

High

P value

PS weighted P

Age, years-no. (%)

 < 55

167 (87.0)

153 (79.7)

0.055

0.906

111 (56.3)

93 (46.7)

0.056

0.984

 ≥ 55

25 (13.0)

39 (20.3)

  

86 (43.7)

106 (53.3)

  

Disease type at screening-no. (%)

Nonvisceral

50 (26.0)

36 (18.8)

0.087

0.934

47 (23.9)

36 (18.1)

0.159

0.992

Visceral

142 (74.0)

156 (81.2)

  

150 (76.1)

163 (81.9)

  

ECOG performance status-no. (%)

0

130 (67.7)

101 (52.6)

0.003

0.853

140 (71.1)

131 (65.8)

0.262

0.991

 ≥ 1

62 (32.3)

91 (47.4)

  

57 (28.9)

68 (34.2)

  

Hormone-receptor status-no. (%)

Positive

95 (49.5)

90 (46.9)

0.069

0.977

99 (50.3)

109 (54.8)

0.420

0.697

Negative

88 (45.8)

100 (52.1)

  

97 (49.2)

90 (45.2)

  

Unknown

9 (4.7)

2 (1.0)

  

1 (0.5)

0 (0)

  

Previous neoadjuvant or adjuvant systemic therapy-no. (%)

No

99 (51.6)

105 (54.7)

0.539

0.927

112 (56.9)

105 (52.8)

0.414

0.986

Yes

93 (48.4)

87 (45.3)

  

85 (43.1)

94 (47.2)

  
  1. Bold indicates P < 0.05
  2. IPTW Inverse probability of treatment weighting, TH group Trastuzumab plus docetaxel group, THP group Pertuzumab plus trastuzumab plus docetaxel