A prospective study on tumour response assessment methods after neoadjuvant endocrine therapy in early oestrogen receptor-positive breast cancer

Table 1 Histopathological information and surgical management of tumours included in our series

Characteristics	Before NET	After NET
Characteristics	(n = 105*)	(n = 104ª)
Histological grade [n (%)]
I	23 (22)	34 (33)
II	78 (74)	69 (66)
III	4 (4)	1 (1)
Histological type [n (%)]
Ductal	86 (82)	85 (82)
Lobular	10 (10)	12 (12)
Other special type	9 (8)	7 (6)
c/yp axillary node status [n (%)]
Negative	91 (87)	72 (69)
Positive	13 (12)	26 (25)
N/A	1 (1)	7 (6)
Positive cells (%) [mean (range)]
Ki67	20 (3–60)	9 (0–75)
Oestrogen receptor	94 (20–100)	90 (0–99)
Progesterone receptor	63 (1–100)	15 (0–99)
Breast surgery performed [n (%)]*
BCS		95 (90)
Modified radical mastectomy		10 (10)

^*One patient was diagnosed with bilateral disease and her two tumours were independently considered in the histopathological analysis and in its surgical management
ªOne tumour was not evaluable for biological characteristics at surgery because the patient achieved a pCR
c/yp axillary node status was determined clinically and pathologically before and after NET, respectively. BCS breast-conserving surgery. N/A not available

ISSN: 1465-542X