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Table 2 Mutual exclusivity analysis of BRCA1, BRCA2, PALB2 mutations among assayed patients

From: Prevalence of BRCA1, BRCA2, and PALB2 genomic alterations among 924 Taiwanese breast cancer assays with tumor-only targeted sequencing: extended data analysis from the VGH-TAYLOR study

A

B

Neither

A Not B

B Not A

Both

Log2 Odds Ratio

p-Value

q-Value

Tendency

BRCA1

BRCA2

851

15

28

13

 > 3

 < 0.001

 < 0.001

Co-occurrence

BRCA1

PALB2

843

20

38

8

 > 3

 < 0.001

 < 0.001

Co-occurrence

BRCA2

PALB2

828

33

38

8

2.401

 < 0.001

 < 0.001

Co-occurrence

  1. Text presented in bold is used to highlight the significance of the p-value
  2. Note: 17 samples were discarded for mutual exclusivity due to missing value in at least one of the interrogated genes
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Breast Cancer Research

ISSN: 1465-542X

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