Fig. 1

SND1 expression correlates to unfavourable prognosis and metastasis of TNBC. A The representative SND1 IHC images of the FFPE samples, 10 case of GBM positive control (GBM), 20 case of TNBC without lymph nodes metastasis (non-Met) and 38 case of TNBC with lymph nodes metastasis (Met). Scale bar: 50 μm. B Compare SND1 positive stain per cent among GBM, non-Met and Met groups of the FFPE samples. Under 10 randomly selected 400 × microscopic fields, the SND1 positive stain percentage was calculated (**, P < 0.01). C K-M survival was plotted based on SND1 level in TNBC patients. Survival in low SND1 subgroup (n = 29) showed more favourable prognosis than SND1 highly expression group (n = 29; P < 0.001). D and E The protein and mRNA levels of SND1 among four individual breast cancer cells (n = 3; **, P < 0.01)