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Table 5 NKI TNBC evaluation set (part of \({\text{val}}_{\rm int}\)) multivariable analysis results - unadjusted with only the analyzed biomarker and adjusted together with the clinical variables age, grade, T-Stage and N-Stage

From: PROACTING: predicting pathological complete response to neoadjuvant chemotherapy in breast cancer from routine diagnostic histopathology biopsies with deep learning

Biomarker

Unadjusted

Adjusted

OR

95% CI

p value

OR

95%CI

p value

vTILs

3.65

1.30–10.22

0.014

2.58*

0.85–7.87

0.095

cTILs

5.03

1.66–15.25

0.004

2.37’

0.69–8.09

0.169

LTR

4.61

1.57–13.50

0.005

4.57’

1.29–16.18

0.019

ITR

2.79

1.02–7.64

0.046

1.70’

0.53–5.48

0.373

MTR

2.23

0.82–6.08

0.116

nc

nc

nc

  1. *adjusted for grade, ’adjusted for grade and T-stage. nc: no change