Fig. 1From: Pubertal exposure to dietary advanced glycation end products disrupts ductal morphogenesis and induces atypical hyperplasia in the mammary glandConsumption of a high AGE diet results in disorganization of the mouse mammary ductal tree. A Schematic representation of experimental design for examining the effect of AGEs upon mammary gland development. B Representative images of carmine stained whole mounts from 7- B and 12- C week old mice fed regular, low AGE or high AGE diet. D Quantification of ductal extension beyond the central lymph node in 7-week old mice. E Quantification of branch points in 7- and 12-week old mice. Scale barā=ā2Ā mm (B) and 50Ā ĀµM (C). Mouse numbers: 7Ā weekāregular (nā=ā4), low AGE (nā=ā5), high AGE (nā=ā5); 12Ā weekāregular (nā=ā4), low AGE (nā=ā4), high AGE (nā=ā4). Values are meanāĀ±āSEM. ***Pā<ā0.05Back to article page