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Fig. 1 | Breast Cancer Research

Fig. 1

From: Loss of SPRY2 contributes to cancer-associated fibroblasts activation and promotes breast cancer development

Fig. 1

SPRY2 expression is decreased in fibroblasts of breast cancers. A SPRY/SPRED family in three Gene Expression Omnibus (GEO) datasets GSE9014, GSE10797 and GSE90505, containing expression profile data of CAFs and matching normal fibroblasts (NF) from breast cancer patients. B Correlation analysis of SPRY2 expression with lymphnode metastasis, tumor size and survival event percentage of patients with BRCA from GSE90505 (Fisher’s exact test). ns non-significant, *P < 0.05, **P < 0.01, ***P < 0.001

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