Name | Mechanism | Cancers studied | References |
---|---|---|---|
p19ARF 26–44 peptide | Binds, localizes FOXM1 to nucleolus | Breast cancer, HCC, ALL | |
Thiozole antibiotics (thiostrepton, siomycin A) | Decrease FOXM1 level | Breast cancer, Ovarian cancer, ALL | |
FDI-6 | Inhibits FOXM1 DNA binding | Breast cancer | [77] |
NB55, NB73, NB115 | Bind FOXM1, decrease FOXM1 level | Breast cancer, Ovarian cancer, Multiple myeloma, Melanoma | |
STL 427944 | Relocates FOXM1 to cytoplasm | Various cancer cells | [82] |
DZY-4 | Inhibits FOXM1 DNA binding | Ovarian cancer | [83] |
FOXM1 PROTACS | Degrade FOXM1 | Breast cancer, Liver cancer, Ovarian cancer |