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Table 1 Combination index

From: Targeting CXCR4 abrogates resistance to trastuzumab by blocking cell cycle progression and synergizes with docetaxel in breast cancer treatment

AMD3100 (µM)

Docetaxel (nM)

CI

0.12

3.7

0.285

0.37

3.7

0.48

1.1

3.7

0.494

3.3

3.7

0.556

10

3.7

0.575

0.12

11

0.409

0.37

11

0.516

1.1

11

0.585

3.3

11

0.605

10

11

0.633

0.12

33

0.457

0.37

33

0.498

1.1

33

0.586

3.3

33

0.609

10

33

0.642

0.12

100

0.413

0.37

100

0.432

1.1

100

0.586

3.3

100

0.619

10

100

0.64

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Breast Cancer Research

ISSN: 1465-542X

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