From: S100A6 inhibits MDM2 to suppress breast cancer growth and enhance sensitivity to chemotherapy
Variable | Total (n = 107) | S100A6 high, no. (%) | S100A6 low, no. (%) | P value | MDM2 high, no. (%) | MDM2 low, no. (%) | P value |
---|---|---|---|---|---|---|---|
S100A6 expression | |||||||
High | 55 |  |  |  | 8 (14.5) | 47 (85.5) |  < 0.0001 |
Low | 52 | Â | Â | Â | 31 (59.6) | 21 (40.4) | Â |
Molecular subtype | |||||||
Luminal (non-HER2 +) | 57 | 28 (49.1) | 29 (50.9) | 0.834 | 21 (36.8) | 36 (63.2) | 0.982 |
HER2 +  | 23 | 13 (56.5) | 10 (43.5) |  | 8 (34.8) | 15 (65.2) |  |
TNBC | 27 | 14 (51.9) | 13 (48.1) | Â | 10 (37.0) | 17 (63.0) | Â |