Fig. 4
PFB-CEUS and MP-MRI images for breast cancer diagnosis. This is a 67-year-old woman with an invasive carcinoma by pathological diagnosis. a At 23 s, the PFB-CEUS had arrived at the peak intensity. The lesion showed a size enlargement on PFB-CEUS compared with gray ultrasound. b TIC of PFB-CEUS shows a 14 s fall time of the lesion. c DWI shows a high signal lesion with an ADC value of 0.77 * 10–3 mm2/s. d DCE-MRI shows patients with mild BPE and a lesion with a noncircumscribed margin. e PFB-CEUS Nomogram shows that this case had a 98% MP at the https://ceus.shinyapps.io/PFB-CEUS/link. f MP-MRI Nomogram shows that this case had a 95% MP at the https://ceus.shinyapps.io/MP-MRI/link. MP-MRI multiparametric magnetic resonance imaging, PFB-CEUS perfluorobutane contrast-enhanced ultrasound, DWI diffusion weighted imaging, ADC apparent diffusion coefficient, DCE-MRI dynamic contrast-enhanced magnetic resonance imaging, BPE background parenchymal enhancement, TIC time–intensity curve, FT fall time, MP malignant probability